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Association of PS1 1/2, ACE I/D, and LRP C/T polymorphisms with Alzheimer�s disease in the Chinese population: a meta-analysis of case-control studies
Authors: L. Yang, H.-H. Zhou, Y.-F. Ye, X.-W. Fan, Y.-J. Wang and Y. Meng
The objective of this study was to assess the associations of presenilin 1 (PS1) 1/2, angiotensin I-converting enzyme (ACE) insertion/deletion (I/D), and low-density lipoprotein receptor-related protein (LRP) C/T polymorphisms with the risk of Alzheimer’s disease (AD) in the Chinese population. PS1 1/2, ACE I/D, and LRP C/T, which are commonly inves.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.6.5
- DOI:
- 10.4238/2015.February.6.5
Bulked segregant analysis for relative water content to detect quantitative trait loci in wheat under drought stress
Authors: M.R. Naroui Rad M. Abdul Kadir M.Y. Rafii H.Z.E. Jaafar M.R. Naghavi
This study was carried out to evaluate the genetic effect of quantitative trait loci (QTLs) conferring drought tolerance in wheat. A population of 120 F2 individuals from the cross between the drought-tolerant S-78-11 and drought-sensitive Tajan cultivars were analyzed for their segregation under drought stress conditions. The relative water content under dr.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.November.12.5
- DOI:
- 10.4238/2012.November.12.5
Isolation and characterization of microsatellite markers for Axonopus compressus (Sw.) Beauv. (Poaceae) using 454 sequencing technology
Authors: X.-L. Wang, Y. Li, L. Liao, C.-J. Bai and Z.-Y. Wang
Axonopus compressus (Sw.) Beauv. is a perennial herb widely used as a garden lawn grass. In this study, we used Roche 454 pyrosequencing, combined with the magnetic bead enrichment method FIASCO, to isolate simple sequence repeat markers from the A. compressus genome. A total of 1942 microsatellite loci were identified, with 53,193 raw sequencing reads. O.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.11.2
- DOI:
- 10.4238/2015.May.11.2
Association of MEF2A gene 3'UTR mutations with coronary artery disease
Authors: X.C. Huang and W. Wang
Association of variants in the myocyte enhancer factor 2A (MEF2A) gene and the risk of coronary artery disease (CAD) has drawn much attention but remains controversial. We hypothesized that the 3'-untranslated region (3'-UTR) of this gene could harbor functionally relevant nucleotide changes. Here, we assessed the association between single nucleotide pol.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.21.20
- DOI:
- http://dx.doi.org/10.4238/2015.September.21.20
Overexpression of NaKR3 enhances salt tolerance in Arabidopsis
Authors: Q. Luo1,2, Z. Zhao1, D.K. Li1, Y. Zhang1, L.F. Xie1, M.F. Peng1, S. Yuan3 and Y. Yang1,2
Salinity is a major abiotic stress in agriculture. Here, we report that SODIUM POTASSIUM ROOT DEFECTIVE3 (NaKR3), which encodes a heavy metal-associated domain protein, is involved in salt tolerance in Arabidopsis. The results of quantitative reverse transcription-polymerase chain reaction analysis revealed that NaKR3 was induced by high salinity and osmo.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15016378
- DOI:
- 10.4238/gmr.15016378
Genetic diversity and taxonomic status of Pinus tabulaeformis f. shekanensis revealed by ISSR markers
Authors: Z.-H. Liu, Q. Xie and Z.-Q. Li
Pinus tabulaeformis f. shekanensis is a rare taxon endemic in the Ziwuling Loess Plateau, of which only one population is known. Inter-simple sequence repeat molecular markers were employed to compare the taxon’s genetic diversity with its 4 nearest wild relatives (P. tabulaeformis, P. tabulaeformis var. mukdensis, P. massoniana, and P. henryi) to a.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.6.7
- DOI:
- 10.4238/2015.February.6.7
Molecular characterization of interferon regulatory factor 1 in Bubalus bubalis
Authors: N.B. Stafuzza, M.M. Borges and M.E.J. Amaral-Trusty
Interferon regulatory factor 1 (IRF1) is functionally diverse in the regulation of immune response and is considered to be an important candidate gene for studying disease susceptibility in mammals. In this paper, we characterized the whole sequence of the IRF1 gene in river buffalo (Bubalus bubalis) and compared genomic and the amino acid sequences betwe.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.21.2
- DOI:
- http://dx.doi.org/10.4238/2015.September.21.2
Values for serum procalcitonin, C-reactive protein, and soluble triggering receptor expressed on myeloid cells-1 in predicting survival of patients with early-onset stroke-associated pneumonia
Authors: J. Xie, X.H. Zhang and W.Y. Zhu
We examined the value of serum procalcitonin (PCT), C-reactive protein (CRP), soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) for predicting the survival of patients with early-onset stroke associated pneumonia (EOP). A total of 207 stroke patients were enrolled, and 91 developed EOP. Upon admission, serum PCT, CRP, sTREM-1 levels, clin.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.11.4
- DOI:
- 10.4238/2015.May.11.4
Quantitative real-time polymerase chain reaction as an efficient molecular tool for detecting minimal residual disease in Moroccan chronic myeloid leukemia patients
Authors: A. Moumen, H. Dehbi, D. Kottwitz, M. El Amrani,N. Bouchoutrouch, H. El Hadi, A. Quessar, S. Benchekroun,S. Nadifi and H. Sefrioui
Chronic myeloid leukemia (CML) is characterized by BCR-ABL translocation and an increased number and migration of immature myeloid cells into the peripheral blood. The detection limit of the BCR-ABL transcript, particularly after treatment, is controversial. In the present study, we used quantitative real-time reverse transcription-polymerase chain reacti.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.6.8
- DOI:
- 10.4238/2015.February.6.8
Identification of differentially expressed genes associated with flower color in peach using genome-wide transcriptional analysis
Authors: Y. Zhou, X.X. Wu, Z. Zhang and Z.H. Gao
Flower color is an important trait of the ornamental peach (Prunus persica L.). However, the mechanism responsible for the different colors that appear in the same genotype remains unclear. In this study, red samples showed higher anthocyanins content (0.122 ± 0.009 mg/g), which was significantly different from that in white samples (0.066 ±.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.11.5
- DOI:
- 10.4238/2015.May.11.5