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Animal Genetics   Research Article

Correlation between adiponectin and hemorrhagic shock in mice

Authors: X. Gong, Y. Liu, S. Yao, J.F. Zheng, F. Wan, X.D. Xiang and X.P. Chai

The aim of this study was to explore the relationship between adiponectin (ADPN) and hemorrhagic shock (HS) and the recovery after HS. This is significant for further understanding of the pathophysiological processes of HS and the development of better treatments. In total, 72 male C57BL/6 mice were assigned randomly to three groups: control, HS, and reco.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017037
DOI:
10.4238/gmr.15017037
Human Genetics   Research Article

Chest wall recurrence location and the lower-bound target of preventive radiotherapy after transverse incision in modified radical mastectomy

Authors: F.P. Wu, J. Wang, H. Wang, Y.J. Liu, N. Li and Z.K. Liu

We investigated the relationship between the lower-bound target of preventive radiation to the chest wall after modified radical mastectomy with a transverse incision and preoperative breast carcinoma characteristics to provide a basis for reducing radiation injury to neighboring tissues and individualizing preventive chest wall radiation targets. We anal.. Read More»

Genet. Mol. Res. 14(1):
2015.February.6.10
DOI:
10.4238/2015.February.6.10
Animal Genetics   Research Article

Effects of propofol and etomidate pretreatment on glucocorticoid receptor expression following induction of sepsis in rats

Authors: C. Wang, N. Liu, R.-M. Li, Y. Zhang, L. Shen and J.-Y. Xiong

The aim of this study was to determine the effect of etomidate and propofol pretreatment on the expression of glucocorticoid receptor and the prognosis of sepsis. The sepsis rat was used as a model. During glucocorticoid treatment, etomidate and propofol were applied alone or together at different time points. Survival curves, glucocorticoid receptor expr.. Read More»

Genet. Mol. Res. 14(2):
2015.May.11.6
DOI:
10.4238/2015.May.11.6
Plant Genetics   Research Article

Changes in inflorescence protein during advanced stages of floret development in Buchloe dactyloides (Poaceae)

Authors: Y.-J. Zhou J.-G. Xue X.-G. Wang X.-Q. Zhang

Buffalograss, Buchloe dactyloides, is a dioecious species native to the Great Plains of North America. The florets at the early stages of development possess both gynoecium and androecium organ primordia but later become unisexual. Very little is known about the proteomic changes that occur when the florets change from hermaph.. Read More»

Genet. Mol. Res. 11(4):
2012.August.17.5
DOI:
10.4238/2012.August.17.5
Human Genetics   Research Article

Highly conserved regions in the 5� region of human olfactory receptor genes

Authors: H.F. Tobar P.A. Moreno P.E. V�©lez

Regulation of human olfactory receptor (hOR) genes is a complex process of control and signalization with various structures and functions that are not clearly understood. To date, nearly 390 functional hOR genes and 462 pseudogenes have been discovered in the human genome. Enhancer models and trans-acting elements for the reg.. Read More»

Genet. Mol. Res. 8(1):
vol8-1gmr550
DOI:
10.4238/vol8-1gmr550
Medical Genetics   Research Article

Effect of single nucleotide polymorphisms in the ATP-binding cassette B1 gene on the clinical outcome of traumatic brain injury

Authors: Z.L. Wang, D.S. Xu, Y.X. Wang, H. Qin and D. Geng

The critical role of ATP-binding cassette B1 (ABCB1) in the function of the blood-brain barrier led us to conducted this prospective study in order to investigate the clinical outcome of patients suffering from severe traumatic brain injury. A total of 182 patients with traumatic brain injury were included in our study. Genotyping of ABCB1 C3435T and G267.. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.21.6
DOI:
http://dx.doi.org/10.4238/2015.September.21.6
Plant Genetics   Research Article

Genetic dissection of upland cotton (Gossypium hirsutum) cultivars developed in Hubei Province by mapped SSRs

Authors: J.L. Tu, M.J. Zhang, X.Q. Wang, X.L. Zhang and Z.X. Lin

The genetic diversity of 51 upland cotton cultivars with different parental origins and breeding periods that were developed in Hubei Province was studied on the basis of 237 mapped simple sequence repeat markers covering the cotton genome. A total of 108 polymorphic primer pairs amplified 196 loci; the polymorphism information content range was 0.04 to 0.83.. Read More»

Genet. Mol. Res. 13(1):
2014.January.31.4
DOI:
10.4238/2014.January.31.4
Bioinformatics   Research Article

Characterization of abnormal epithelium after laser-assisted subepithelial keratectomy using in vivo confocal microscopy

Authors: J. Zuo, C.W. Zhang, X. Zhou, W. Wei and Y.L. Wang

This study compared the abnormal corneal epithelium after laser-assisted subepithelial keratectomy (LASEK) with dystrophic cornea using in vivo using confocal microscopy (IVCM) and examined the effects of the abnormal epithelium on postoperative recovery of uncorrected distance visual acuity (UDVA) and sub-basal nerve plexus regeneration. The UDVA and wou.. Read More»

Genet. Mol. Res. 14(2):
2015.May.11.7
DOI:
10.4238/2015.May.11.7
Human Genetics   Research Article

Specific BRCA1 gene variations amongst young Moroccan breast cancer patients

Authors: A. Tazzite, S. Nadiffi, D. Kottwitz, M. El Amrani, H. Jouhadi,A. Benider, A. Moumen4 and H. Sefrioui

Germline mutations in the BRCA1 gene are known predictive markers for the development of hereditary breast cancer. Nevertheless, no comprehensive study has been performed targeting the presence and relevance of BRCA1 mutations in Moroccan breast cancer patients. We here present an analysis of BRCA1 gene regions (exon 2 and exo.. Read More»

Genet. Mol. Res. 13(1):
http://dx.doi.org/2014.January.31.5
DOI:
http://dx.doi.org/10.4238/2014.January.31.5
Human Genetics   Research Article

G501C polymorphism of the oxidized LDL receptor gene is associated with albuminuria in Chinese essential hypertension patients

Authors: X.W. Hou, Z.H. Hu, Y. Cui, W. Gao, S.P. Sun and N.F. Wang

Albuminuria is an independent predictor of renal and cardiovascular complications in hypertensive subjects. We previously showed that lectin-like oxidized low-density lipoprotein receptor 1 (OLR-1) polymorphisms at G501C are associated with susceptibility to essential hypertension and serum C-reactive protein levels. We have n.. Read More»

Genet. Mol. Res. 10(4):