Se
Association between matrix metalloproteinase-3 polymorphism and anterior cruciate ligament ruptures
Authors: S. Malila, P. Yuktanandana, S. Saowaprut, W. Jiamjarasrangsi and S. Honsawek
Anterior cruciate ligament (ACL) ruptures are considered to be the most severe joint injury in sports. However, the precise etiologies of ACL injuries are not fully understood. Recently, the gene encoding the matrix metalloproteinase-3 (MMP-3, stromelysin-1) was shown to be associated with anterior cruciate ligament ruptures. .. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.31.1
- DOI:
- 10.4238/2011.October.31.1
Prevalence of vitamin D receptor gene polymorphism in a Uruguayan population and its relation to type 1 diabetes mellitus
Authors: Mimbacas A, Trujillo J, Gascue C, Javiel G and Cardoso H
Vitamin D has important immuno-modulatory properties and it influences insulin secretion. It acts through a vitamin D receptor (VDR), for which several gene polymorphisms have been described. The Uruguayan population presents several epidemiological characteristics that make it different from that of other counties, including .. Read More»
- Genet. Mol. Res. 6(3):
Microbial diversity in the larval gut of field and laboratory populations of the sugarcane weevil Sphenophorus levis (Coleoptera, Curculionidae)
Authors: R. Rinke, A.S. Costa, F.P.P. Fonseca, L.C. Almeida, I. Delalibera J�ºnior and F. Henrique-Silva
The sugarcane weevil, Sphenophorus levis, is a wide-spread sugarcane pest in Brazil. Sphenophorus levis may depend on microorganisms that inhabit its intestinal tract. We examined the diversity of the gut microbiota of S. levis, which was characterized using culture-dependent and culture-independent methods. Analysis of 16S rR.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.November.1.1
- DOI:
- 10.4238/2011.November.1.1
Early diagnosis of a Mexican variant of Papaya meleira virus (PMeV-Mx) by RT-PCR
Authors: E. Zamudio-Moreno, J.H. Ramirez-Prado, O.A. Moreno-Valenzuela and L.A. Lopez-Ochoa
Papaya meleira disease was identified in Brazil in the 1980s. The disease is caused by a double-stranded RNA virus known as Papaya meleira virus (PMeV), which has also been recently reported in Mexico. However, previously reported PMeV primers failed to diagnose the Mexican form of the disease. A genomic approach was used to identify sequences of the Mexi.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.6.18
- DOI:
- 10.4238/2015.February.6.18
A novel missense mutation in exon 7 of the ECM1 gene in an Iranian lipoid proteinosis patient
Authors: F. Izadi F. Mahjoubi M. Farhadi M.M. Tavakoli S. Samanian
Lipoid proteinosis (LP) is a rare autosomal recessive disorder. Classical clinical features include warty skin infiltration, papules on the eyelids, skin scarring, as well as extracutaneous abnormalities such as hoarseness of the voice, epilepsy, and neuropsychiatric abnormalities. A defect in the ECM1 gene is responsible for this disease. A 21-year-old fema.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.November.14.2
- DOI:
- 10.4238/2012.November.14.2
Relationship between serum adiponectin and osteoprotegerin levels and coronary heart disease severity
Authors: H.L. Zhang and X. Jin
This study aimed to explore serum adiponectin and osteoprotegerin levels in patients with coronary heart disease (CHD) and their correlation with inflammatory and ischemia factors. From September 2010 to Augest 2010, 347 CHD patients were enrolled for a retrospective analysis. Serum lipoprotein phospholipase A2 (Lp-PLA2), hypersensitive C-reactive protein.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.21.15
- DOI:
- http://dx.doi.org/10.4238/2015.September.21.15
Transferability of SSR markers from related Uredinales species to the coffee rust Hemileia vastatrix
Authors: M. Cristancho and C. Escobar
The aim of the present research was to test the transferability of simple sequence repeat (SSR) markers developed in two Uredinales species to Hemileia vastatrix, coffee rust. The development of efficient techniques for the identification of H. vastatrix isolates is imperative, given the continuous development of new races. The transferability of 25 SSR m.. Read More»
- Genet. Mol. Res. 7(4):
- vol7-4gmr493
- DOI:
- 10.4238/vol7-4gmr493
Isolation and characterization of 24 polymorphic microsatellite loci in Sepioteuthis lessoniana
Authors: X.-D. Zheng Z.-R. Zuo X.-J. Su Q. Li
Owing to their codominant, multiallelic, and highly polymorphic nature, microsatellite markers have been used widely in population genetics and biological resource conservation studies. To investigate the genetic structure of Sepioteuthis lessoniana, we developed 24 microsatellite DNA markers and assessed the polymorphism of each locus in a wild S. lessonian.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.November.14.3
- DOI:
- 10.4238/2012.November.14.3
Differentially expressed genes implicated in embryo abortion of mango identified by suppression subtractive hybridization
Authors: J.H. He F.W. Ma Y.Y. Chen H.R. Shu
Embryo abortion in mango severely damages mango production worldwide. The mechanisms by which the mango embryos abort have long been an intriguing question. We used subtractive suppression hybridization to investigate the differentially expressed genes involved in this process. We generated 2 cDNA libraries from normal seed and aborted seed embryos of mango .. Read More»
- Genet. Mol. Res. 11(4):
- 2012.November.14.4
- DOI:
- 10.4238/2012.November.14.4
Selection and validation of reference houseÃ?Âkeeping genes in the J774A1 macrophage cell line for quantitative real-time PCR
Authors: F.B. Ferraz and J.H. Fernandez
Macrophages are essential components of the innate and adaptive immune responses, playing a decisive role in atherosclerosis, asthma, obesity, and cancer. The differential gene expression resulting from adhesion of macrophages to the extra-cellular matrix (ECM) has been studied in the J774A1 murine macrophage cell line using quantitative polymerase chain .. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017720
- DOI:
- 10.4238/gmr.15017720