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Human Genetics   Research Article

Effects of conservative laparoscopic endometrial cystectomy and use of kidney-reinforcing and blood activating traditional Chinese medicine on ovarian functions

Authors: Y.H. Huang, L. Shen, A.H. Cai and X.F. Liang

This study investigated functional changes in the ovaries of women who have had conservative laparoscopic endometrial cystectomy and the effects of traditional kidney-reinforcing and blood-activating Traditional Chinese Medicine (TCM) on ovarian function. Seventy female patients who underwent laparoscopic endometrial cystectomy were randomized into two group.. Read More»

Genet. Mol. Res. 14(1):
2015.January.30.6
DOI:
10.4238/2015.January.30.6
Bioinformatics   Research Article

Genome sequence compression based on optimized context weighting

Authors: M. Chen, J.J. Shao and X.M. Jia

Context weighting is an important technology for genome compression. In this study, we discuss the relationship between the weighting of context models and the weighting of the description lengths corresponding to their respective context models. It indicates that weighting of context models is equivalent to the weighting of t.. Read More»

Genet. Mol. Res. 16(2):
gmr16026784
DOI:
10.4238/gmr16026784
Plant Genetics   Research Article

Selection between and within full-sib sugarcane families using the modified BLUPIS method (BLUPISM)

Authors: R.D. Castro1, L.A. Peternelli1, M.D.V. Resende2, C.D. Marinho1, P.M.A. Costa1, M.H.P. Barbosa3 and E.F.A. Moreira1

The objective of this study was to assess the efficiency of a modification of the simulated individual best linear unbiased prediction (BLUPIS) procedure, which is used for the approximation of classic individuals (BLUPI) for selection between and within sugarcane families. A total of 110 full-sib families were employed in an experiment initiated in 2007 .. Read More»

Genet. Mol. Res. 15(1):
gmr.15017334
DOI:
10.4238/gmr.15017334
Human Genetics   Research Article

CYP4F2 gene single nucleotide polymorphism is associated with ischemic stroke

Authors: H.-Q. Yan, Y. Yuan, P. Zhang, Z. Huang, L. Chang and Y.-K. Gui

The objective of this study was to explore the relationship between CYP4F2 gene polymorphism and ischemic stroke (IS) in the Han Chinese population. We performed a case-control study to genotype four single nucleotide polymorphisms (SNPs) (rs2108622, rs3093100, rs3093105, rs3093135) in the CYF4F2 gene. The genotype and haplotype distributions were compare.. Read More»

Genet. Mol. Res. 14(1):
2015.January.30.8
DOI:
10.4238/2015.January.30.8
Plant Genetics   Research Article

Comparison of a retrotransposon-based marker with microsatellite markers for discriminating accessions of Vitis vinifera

Authors: G.C. Santâ��Ana, J.L. Ferreira, H.S. Rocha, A. Bor�©m, M. Pasqual and G.M.A. Can�§ado

Identification and knowledge concerning genetic diversity are fundamental for efficient management and use of grapevine germplasm. Recently, new types of molecular markers have been developed, such as retrotransposon-based markers. Because of their multilocus pattern, retrotransposon-based markers might be able to differentiat.. Read More»

Genet. Mol. Res. 11(2):
2012.May.21.8
DOI:
10.4238/2012.May.21.8
Human Genetics   Research Article

Identification of hub genes and pathways associated with retinoblastoma based on co-expression network analysis

Authors: Q.L. Wang, X. Chen, M.H. Zhang, Q.H. Shen, Z.M. Qin

The objective of this paper was to identify hub genes and pathways associated with retinoblastoma using centrality analysis of the co-expression network and pathway-enrichment analysis. The co-expression network of retinoblastoma was constructed by weighted gene co-expression network analysis (WGCNA) based on differentially ex.. Read More»

Genet. Mol. Res. 14(4):
2015.December.8.4
DOI:
10.4238/2015.December.8.4
Animal Genetics   Research Article

Single nucleotide polymorphisms associated with growth traits in Jinghai yellow chickens

Authors: M.A. Abdalhag,T. Zhang, Q.C. Fan, X.Q. Zhang, G.X. Zhang, J.Y. Wang, Y. Wei,Y.J. Wang

Body weight is one of the most important economic traits in the poultry industry. In the present study, a custom SNP Beadchip was used to analyze the association between those 15 SNPs and 12 growth traits of Jinghai yellow chickens, and other important genetic parameters were also calculated and analyzed. The results indicated.. Read More»

Genet. Mol. Res. 14(4):
2015.December.8.6
DOI:
10.4238/2015.December.8.6
Animal Genetics   Original Articles

Uneven evolutionary rate of the melatonin-related receptor gene (GPR50) in primates

Authors: Y. Zhang, H.Q. Li, Y.F. Yao, W. Liu, Q.Y. Ni, M.W. Zhang and H.L. Xu1,

The melatonin-related receptor GPR50 plays an important role in mammalian adaptive thermogenesis in response to calorie intake. The evolutionary history of the GPR50 gene is poorly understood in primates; however, it has been reported that GPR50 is the mammalian ortholog of Mel1c, which has been well characterized. In this study, the complete coding sequence.. Read More»

Genet. Mol. Res. 14(1):
2015.January.30.11
DOI:
10.4238/2015.January.30.11
Plant Genetics   Research Article

Screening of molecular markers linked to dwarf trait in crape myrtle by bulked segregant analysis

Authors: Y.J. Ye, Y. Liu, M. Cai, D. He, J.S. Shen, Y.Q. Ju, X.M. Bian,H.T. Pan and Q.X. Zhang

Plant height is one of the most important traits of plant architecture as it modulates both economic and ornamental values. Crape myrtle (Lagerstroemia indica L.) is a popular ornamental woody plant because of its long-lasting mid-summer bloom, rich colors, and diversified plant architecture. These traits also make it an ideal model of woody species for g.. Read More»

Genet. Mol. Res. 14(2):
2015.April.30.10
DOI:
10.4238/2015.April.30.10
Microbial Genetics   Research Article

Allele frequencies of microsatellite loci for genetic characterization of a Sicilian bovine population

Authors: M. Cosenza, S. Reale, T. Lupo, F. Vitale and S. Caracappa

Short tandem repeats are used as an effective method to trace DNA markers in genotyping. Using a standardized kit, we tested 11 microsatellite markers recommended by the International Society for Animal Genetics (ISAG) in a sample of 495 Sicilian cattle. The aim of this study was to investigate the allele frequencies in the Sicilian cattle population to prov.. Read More»

Genet. Mol. Res. 14(1):
2015.January.30.12
DOI:
10.4238/2015.January.30.12