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Human Genetics   Research Article

Genetic diversity and population structure in Brazilian Mangalarga Marchador horses

Authors: J.B. DeAssis, D.M. DeLaat, M.G.C.D. Peixoto, J.A.G. Bergmann,C.G. Fonseca and M.R.S. Carvalho

One hundred and fifteen unrelated Mangalarga Marchador horses were sampled from three geographically distinct regions of Minas Gerais State, Brazil (South, Southeast, and Northeast) and tested for 10 microsatellite loci. Genetic diversity and population structure parameters were estimated with ARLEQUIN 3.0, CERVUS 2.0, POPGENE.. Read More»

Genet. Mol. Res. 8(4):
vol8-4gmr647
DOI:
10.4238/vol8-4gmr647
Plant Genetics   Research Article

New set of microsatellites for Chinese tallow tree, Triadica sebifera

Authors: Y.F. Zhuang, Z.F. Wang and L.F. Wu

Chinese tallow (Triadica sebifera) is an important crop and ornamental tree. After it was introduced into the USA, it gradually became a noxious invasive tree in south-eastern America since the middle of the 1900s. Because only six microsatellites were reported previously in T. sebifera, to better understand the genetic divers.. Read More»

Genet. Mol. Res. 16(2):
gmr16029624
DOI:
10.4238/gmr16029624
Animal Genetics   Research Article

Brazilian strain of bovine respiratory coronavirus is derived from dual enteric and respiratory tropism

Authors: E.A. Beuttemmuller, A.F. Alfieri, S.A. Headley and A.A. Alfieri

Bovine coronavirus (BCoV) is a pathogen related to enteric and respiratory diseases in cattle worldwide. Enteric (BECoV) strains of BCoV are predominant in South America, and genetic investigations have been conducted to identify its relationship with isolates of respiratory origin (BRCoV). In this study, we used a BRCoV strai.. Read More»

Genet. Mol. Res. 16(2):
gmr16029580
DOI:
10.4238/gmr16029580
Human Genetics   Research Article

Dietary carotenoid-rich pequi oil reduces plasma lipid peroxidation and DNA damage in runners and evidence for an association with MnSOD genetic variant -Val9Ala

Authors: A.L. Miranda-Vilela, A.K. Akimoto, P.C.Z. Alves, L.C.S. Pereira,C.A. Gon�§alves, M.N. Klautau-Guimar�£es and C.K. Grisolia

Physical training induces beneficial adaptations; however, exhausting exercise increases reactive oxygen species generation, resulting in damage to DNA and tissues. Pequi (Caryocar brasiliense), a fruit of the Brazilian Cerrado, contains a carotenoid-rich oil. We investigated whether pequi oil had antioxidant effects in runner.. Read More»

Genet. Mol. Res. 8(4):
Plant Genetics   Research Article

New sources of resistance to leafminers (Liriomyza sativae) in melon (Cucumis melo L.) germplasm

Authors: E.F. Celin, F.I.C. Oliveira, N.S. Dias-Pini, G.H.S. Nunes and F.A.S. Arag�£o

Leafminers (Liriomyza sativae) are the main melon (Cucumis melo L.) pests in Northeast Brazil, which is the main region for the production and export of the fruit in Brazil. Of the integrated management strategies available, genetic resistance is the best method of preventing damage by these insects. The aim of this study was .. Read More»

Genet. Mol. Res. 16(2):
gmr16029561
DOI:
10.4238/gmr16029561
Medical Genetics   Research Article

Estimation of genetic distance between 10 maize accessions with varying response to different levels of soil moisture

Authors: M. Aslam, F.S. Awan, I.A. Khan and A.I. Khan

Ten maize accessions (NC-9, A50-2, M-14, B-42, NC-3, T-7, N-48-1, B-34, USSR, and WFTMS) were studied to estimate the genetic distance on molecular level by random amplified polymorphic DNA. These accessions were selected on the basis of their variable responses against different levels of moisture. Twenty-five primers were us.. Read More»

Genet. Mol. Res. 8(4):
vol8-4gmr606
DOI:
10.4238/vol8-4gmr606
Human Genetics   Research Article

Association between TNF-�±rs1799724 and rs1800629 polymorphisms and the risk of Crohnâ��s disease

Authors: Y.Q. Mao, S.Q. Dong, M. Gao

We investigated the associations between 2 major tumor necrosis factor-α (TNF-α) polymorphisms, rs1799724 C>T and rs1800629 G>A, and the susceptibility to Crohn’s disease (CD) using a meta-analysis framework. The PubMed, EBSCO, Ovid, Wiley, Web of Science, WANFANG, and VIP databases (last updated search.. Read More»

Genet. Mol. Res. 14(4):
2015.December.1.33
DOI:
10.4238/2015.December.1.33
Animal Genetics   Research Article

Expression of the ROR�± gene in Inner Mongolian cashmere goat hair follicles

Authors: Y.H. Zhao, Z.H. Liu, L. Wang, H.M. Xiao, C.G. Du, Y.J. Zhang,R. Su and J.Q. Li

The expression of retinoid-acid-related orphan receptor Ã?± (RORÃ?±) was evaluated at the mRNA level using real-time polymerase chain reaction (qRT-PCR), and its expression localization was determined by in situ hybridization of adult Inner Mongolian cashmere goats at different times of the year. In situ hybridization demonstrated that RORÃ?±was expressed.. Read More»

Genet. Mol. Res. 14(1):
2015.January.23.11
DOI:
10.4238/2015.January.23.11
Human Genetics   Research Article

Molecular characterization, tissue expression, and polymorphism analysis of liver-type fatty acid binding protein in Landes geese

Authors: Z. Song, D. Shao, X.X. Sun, J.W. Niu and D.Q. Gong

Liver weight is an important economic trait in the fatty goose liver industry. Liver-type fatty acid binding protein (L-FABP) is involved in the formation and metabolism of fatty acids. Thus, we hypothesized that sequence polymorphisms in L-FABP were associated with fatty liver weight in goose. We first isolated, sequenced, and characterized the goose L-F.. Read More»

Genet. Mol. Res. 14(1):
2015.January.23.12
DOI:
10.4238/2015.January.23.12
Human Genetics   Research Article

JNK pathway and relative transcriptional factor were involved in ginsenoside Rh2-mediated G1 growth arrest and apoptosis in human lung adenocarcinoma A549 cells

Authors: X. Liu, Y. Sun, L. Yue, S. Li, X. Qi, H. Zhao, Y. Yang, C. Zhang and H. Yu

Ginsenoside Rh2 has been shown to have an anti-tumor effect on a wide range of cancers. A previous study has shown that ginsenoside Rh2 can inhibit the proliferation of the human lung adenocarcinoma A549 cell line in a dose-dependent manner byactivating caspase-8/3 activity to promote apoptosis. However, the association of the JNK signaling pathways and t.. Read More»

Genet. Mol. Res. 15(3):
gmr.15039003
DOI:
10.4238/gmr.15039003