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Genetic association between the HLA-G 14-bp insertion/deletion polymorphism and the recurrent spontaneous abortions in Saudi Arabian women
Authors: S.Y. Al Omar, L. Mansour, A.F. Alkhuriji, S. Alwasel and S. Al-Qahtani
The non-classical class I human leukocyte antigen (HLA)-G molecule was found to be predominately expressed in the extravillous cytotrophoblasts at the fetal-maternal interface during pregnancy. This molecule is critically important for successful implantation during human pregnancy. The polymorphic insertion-deletion (indel) 14-base pair (bp) site localiz.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.23.2
- DOI:
- 10.4238/2015.January.23.2
Genetic diversity analysis of Croton antisyphiliticus Mart. using AFLP molecular markers
Authors: T.G. Oliveira1, A.M.S. Pereira2, J.S. Coppede2, S.C. Fran�§a2, L.C. Ming1 and B.W. Bertoni2
Croton antisyphiliticus Mart. is a medicinal plant native to Cerrado vegetation in Brazil, and it is popularly used to treat urogenital tract infections. The objective of the present study was to assess the genetic variability of natural C. antisyphiliticus populations using AFLP molecular markers. Accessions were collected in the states of Minas Gerais, .. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017461
- DOI:
- 10.4238/gmr.15017461
Identification of novel and useful EST-SSR markers from de novo transcriptome sequence of wheat (Triticum aestivum L.)
Authors: Z.J. Yang, Z.S. Peng and H. Yang
Simple sequence repeats (SSRs) are highly informative, polymorphic, and co-dominant Mendelian markers that provide an important genomic resource for genetic research. Recently, the use of large-scale transcriptome sequence has become a reliable and efficient approach for the identification and development of new EST-SSR markers. In this study, 8389 potent.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017509
- DOI:
- 10.4238/gmr.15017509
Development of microsatellite markers in the tetraploid fern Ceratopteris thalictroides (Parkeriaceae) using RAD tag sequencing
Authors: X.Y. Yang1*, Z.C. Long2*, A.W. Gichira2, Y.H. Guo1, Q.F. Wang2 and J.M. Chen2
To understand the genetic variability of the tetraploid fern Ceratopteris thalictroides (Parkeriaceae), we described 30 polymorphic microsatellite markers obtained using the restriction site-associated DNA (RAD) tag sequencing technique. A total of 26 individuals were genotyped for each marker. The number of alleles per locus ranged from 4 to 10, and the .. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017550
- DOI:
- 10.4238/gmr.15017550
Iron translocation in Pleurotus ostreatus basidiocarps: production, bioavailability, and antioxidant activity
Authors: M.E. Yokota1, P.S. Frison1, R.C. Marcante1, L.F. Jorge1, J.S. Valle1, D.C. Dragunski2, N.B. Colauto1 and G.A. Linde10
Translocation of minerals from substrate to mushrooms can change the medicinal characteristics, commercial value, and biological efficiency of mushroom. In the present study, we demonstrated that addition of iron to the substrate reduces the yield of Pleurotus ostreatus mushroom. The biological efficiency of the mushroom varied from 36.53% on the unsupple.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017888
- DOI:
- 10.4238/gmr.15017888
Cloning and characterization of defense-related genes from Populus szechuanica infected with rust fungus Melampsora larici-populina
Authors: Z.J. Chen1,2, Z.M. Cao1, Z.D. Yu1 and D. Yu1
Characterization of defense-related genes is critical for breeding disease-resistant poplar varieties and for better management and control of leaf rust disease. In the present study, full-length cDNAs of five Populus szechuanica defense-related (PsDR) genes, pathogen-related protein 1 (PsPR1), β-1,3-glucanase (PsGns), thaumatin-like protein 1 (PsTLP.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017314
- DOI:
- 10.4238/gmr.15017314
Abundance and diversity of resistance genes in the sugarcane transcriptome revealed by in silico analysis
Authors: A.C. Wanderley-Nogueira, N.M. Soares-Cavalcanti, D.A.L. Morais, L.C. Belarmino, A. Barbosa-Silva and A.M. Benko-Iseppon
Resistance genes (R-genes) are responsible for the first interaction of the plant with pathogens being responsible for the activation (or not) of the defense response. Despite their importance and abundance, no tools for their automatic annotation are available yet. The present study analyzed R-genes in the sugarcane expressed.. Read More»
- Genet. Mol. Res. 6(4):
miRNApath: a database of miRNAs, target genes and metabolic pathways
Authors: A.O. Chiromatzo, T.Y.K. Oliveira, G. Pereira, A.Y. Costa, C.A.E. Montesco, D.E. Gras, F. Yosetake, J.B. Vilar, M. Cervato, P.R.R. Prado, R.G.C.C.L. Cardenas, R. Cerri, R.L. Borges, R.N. Lemos, S.M. Alvarenga, V.R.C. Perallis, D.G. Pinheiro, I.T. Silva, R.M. Brand�£o, M.A.V. Cunha, S. Giuliatti and W.A. Silva Jr
MicroRNAs (miRNAs) are small non-coding RNAs that regulate target gene expression and hence play important roles in metabolic pathways. Recent studies have evidenced the interrelation of miRNAs with cell proliferation, differentiation, development, and diseases. Since they are involved in gene regulation, they are intrinsicall.. Read More»
- Genet. Mol. Res. 6(4):
Marker-trait association analysis for agronomic and compositional traits in sainfoin (Onobrychis viciifolia)
Authors: K. Kempf, C.S. Malisch, C. Grieder, F. Widmer and R. K�¶lliker
Sainfoin (Onobrychis viciifolia) is a perennial forage legume with great potential for use in sustainable agriculture due to its low input requirements, good drought tolerance, and production of forage rich in polyphenolic compounds, which are beneficial for animal health. However, its distribution and cultivation are limited .. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019483
- DOI:
- 10.4238/gmr16019483
Impact of early enzyme-replacement therapy for mucopolysaccharidosis VI: results of a long-term follow-up of Brazilian siblings
Authors: J.F. Franco1, D.C. Soares1, L.C. Torres2, G.N. Leal1, M.T. Cunha1,R.S. Honjo1, D.R. Bertola1 and C.A. Kim1
Mucopolysaccharidosis type VI (MPS VI) is an autosomal recessive multisystem lysosomal storage disorder, which is characterized by the deficiency of the enzyme arylsulfatase B encoded by the ARSB gene. Treatment of this disease with enzyme-replacement therapy (ERT) improves the clinical status of and generates hope for MPS VI patients. However, only few r.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017850
- DOI:
- 10.4238/gmr.15017850