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Effects of Mycoplasma pneumoniae infection on airway neurokinin-1 receptor expression in BALB/c mice

Authors: H. Zhang1, B. Wei2, Y.X. Shang1, X.Y. Jiao1, L. Wang1, M.B. He3, X.H. Han1 and G.Z. Wang3

The aim of this study was to establish a BALB/c mouse model of Mycoplasma pneumoniae (MP) infection and to explore the expression of neurokinin-1 receptor (NK1-R) in the trachea and lung tissue and changes in its relative content at different time points (on the 3rd, 7th, 14th, 21st, and 30th days after infection) in MP-infected BALB/c mice. Immunohistoch.. Read More»

Genet. Mol. Res. 13(4):

2014.October.20.8

DOI:

10.4238/2014.October.20.8

Variability with altitude of major histocompatibility complex-related microsatellite loci in goats from Southwest China

Authors: G.X. E, Y.F. Huang, Y.J. Zhao and R.S. Na

We aimed to use microsatellite BM1258 loci of the major histocompatibility complex (MHC) as an indicator of the influence of genetic diversity of immunity in goats (Dazu Black, Hechuan White, Meigu, and Tibetan goat). In total, 132 animals comprising 50 Dazu Black goats, 24 Hechuan White goats, 34 Meigu goats, and 24 Tibetan goats were examined. Collectiv.. Read More»

Genet. Mol. Res. 14(4):

2015.November.18.26

DOI:

10.4238/2015.November.18.26

APOA5 -1131T/C polymorphism and coronary artery disease susceptibility in Chinese population: an updated meta-analysis and review

Authors: J. Zhang, D.G. Wan, H.L. Song and W.G. Zhang

Although many studies have investigated the association of the APOA5 -1131T/C polymorphism with coronary artery disease (CAD), definite conclusions have not been drawn. To understand the effects of the APOA5 -1131T/C polymorphism on the risk of developing CAD, we performed an updated meta-analysis in the Chinese population. Re.. Read More»

Genet. Mol. Res. 14(4):

2015.October.9.22

DOI:

10.4238/2015.October.9.22

Cloning and sequence analysis of the coding sequence of �²-actin cDNA from the Chinese alligator and suitable internal reference primers from the �²-actin gene

Authors: H.N. Zhu, S.Z. Zhang, Y.K. Zhou, C.L. Wang and X.B. Wu

β-Actin is an essential component of the cytoskeleton and is stably expressed in various tissues of animals, thus, it is commonly used as an internal reference for gene expression studies. In this study, a 1731-bp fragment of β-actin cDNA from Alligator sinensis was obtained using the homology cloning technique. Sequ.. Read More»

Genet. Mol. Res. 14(4):

2015.October.9.4

DOI:

10.4238/2015.October.9.4

Effectiveness of bacterial infection-related cytokine profile (BIRCP) determination for monitoring pathogen infections in children with hemopathy in the bone marrow inhibition phase

Authors: X.D. Chen, B. Chen, Y.M. Tang, H. Song, S.W. Shi, S.L. Yang, W.Q. Xu, B.H. Pan, F.Y. Zhao, N. Zhao, L.Y. Zhang and J.Q. Mao

Genet. Mol. Res. 13(4):

Etiological factors, prognostic assessment, and outcomes of patients with acute kidney injury and multiple organ dysfunction syndrome

Authors: Z. Gao1, D.W. Mu2, L. Guo3, X.M. Li1 and L.D. Lun1

This clinical study assessed the etiological factors implicated in acute kidney injury (AKI). AKI has a complicated etiology with many serious complications. Understanding the interactions among these factors will help physicians treat patients with AKI. This retrospective study analyzed the etiological factors and assessed the incidence and outcome of 12.. Read More»

Genet. Mol. Res. 13(4):

/2014.October.20.13

DOI:

/10.4238/2014.October.20.13

Interaction of six candidate genes in essential hypertension

Authors: D.C. Hu, X.L. Zhao, J.C. Shao, W. Wang, J. Qian, A.H. Chen, H.Q. Zhang, H. Guo, J. Jiang and H.Y. Li

We explored the interaction of 6 candidate genetic mutations in essential hypertension (EH). The mutations AGT M235T, ACE I/D, eNOS Glu298Asp, ET-2 A985G, ANP T2238C, and NPRC A-55C were detected using a genechip microarray in 100 patients with EH and 97 controls from the Han population living in the Yunnan Province of China. Risks of EH were evaluated wi.. Read More»

Genet. Mol. Res. 13(4):

2014.October.20.14

DOI:

10.4238/2014.October.20.14

Single- and double-SSR primer combined analyses in rice

Authors: J. Ma, S.C. Guan, Z. Zhang and P.W. Wang

Polymerase chain reaction (PCR) is the foundation of SSR molecular marker technology. We used sib rice varieties J518, XD1 and SD23 as experimental materials, selecting 30 pairs of SSR primers, including RM127, RM337 and RM5172, covering the rice genome, and performed single- and double-SSR primer combined analyses. We found t.. Read More»

Genet. Mol. Res. 11(2):

2012.April.27.1

DOI:

10.4238/2012.April.27.1

An AFLP-based approach for the identification of sex-linked markers in blunt snout bream, Megalobrama amblycephala (Cyprinidae)

Authors: H.O. Rao, J.C. Deng, W.M. Wang and Z.-X. Gao

Sex-specific DNA markers are useful for studying sex-determination mechanisms and establishment of monosex populations. Three widely spaced geographical populations (Liangzi, Poyang and Yuni Lakes in China) of blunt snout bream (Megalobrama amblycephala) were screened with AFLPs to search for sex-linked markers. Female and mal.. Read More»

Genet. Mol. Res. 11(2):

2012.April.19.7

DOI:

10.4238/2012.April.19.7

Effects of various salinities on Na+-K+-ATPase, Hsp70 and Hsp90 expression profiles in juvenile mitten crabs, Eriocheir sinensis

Authors: M. Sun, K. Jiang, F. Zhang, D. Zhang, A. Shen, M. Jiang, X. Shen and L. Ma

Eriocheir sinensis is a euryhaline crab migrating from sea to freshwater habitats during the juvenile stage. We used quantitative real-time polymerase chain reaction (qRT-PCR) to investigate the gene expression profile of Na+-K+-ATPase, Hsp70 (heat shock protein 70) and Hsp90 in megalopa exposed to salinities of 0, 2, 5, 10, a.. Read More»

Genet. Mol. Res. 11(2):

2012.April.19.3

DOI:

10.4238/2012.April.19.3