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Association of a miR-34b binding site single nucleotide polymorphism in the 3'-untranslated region of the methylenetetrahydrofolate reductase gene with susceptibility to male infertility
Authors: W. Zhang, W.-Q. Lin, H.-F. Cao, C.-Y. Li and F. Li
This study aims to explore the possible associations between a genetic variation in the miR-34b binding site in the 3'-untranslated region (UTR) of the methylenetetrahydrofolate reductase (MTHFR) gene (rs55763075) with male infertility in a Chinese population. Genotype distributions of the rs55763075 single nucleotide polymorp.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.9.8
- DOI:
- 10.4238/2015.October.9.8
Phylogenetic analysis of Elymus (Poaceae) in western China
Authors: H. Song, Z.B. Nan and P. Tian
Elymus L. is often planted in temperate and subtropical regions as forage. Species in the genus have 5 allopolyploid genomes that are found in the grass tribe Triticeae. To determine the phylogenetic relationships in Elymus species from western China, we estimated phylogenetic trees using sequences from the nuclear ribosomal i.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.9.11
- DOI:
- 10.4238/2015.October.9.11
Strategies in identifying individuals in a segregant population of common bean and implications of genotype x environment interaction in the success of selection
Authors: M.P. Mendes, M.A.P. Ramalho and A.F.B. Abreu
The objective of this study was to compare the BLUP selection method with different selection strategies in F2:4 and assess the efficiency of this method on the early choice of the best common bean (Phaseolus vulgaris) lines. Fifty-one F2:4 progenies were produced from a cross between the CVIII8511 x RP-26 lines. A randomized .. Read More»
- Genet. Mol. Res. 11(2):
- 2012.April.10.3
- DOI:
- 10.4238/2012.April.10.3
Lack of an association between matrix metalloproteinase polymorphisms and coronary heart disease in a Han Chinese population
Authors: C.M. Wang, H.D. Ye, Y.R. Li, Q.X. Hong, L.L. Tang, A.N. Zhou, M.Q. Xu and S.W. Duan
Coronary heart disease (CHD) has become a leading cause of human deaths worldwide. Recent studied showed that polymorphisms of the matrix metalloproteinase (MMP) genes played important roles in extracellular matrix remodeling and contribute to the pathogenesis of vascular diseases. Here, we investigated whether these MMP gene .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.9.14
- DOI:
- 10.4238/2015.October.9.14
Comparative characteristics of DNA polymorphisms of �º-casein gene (CSN3) in the horse and donkey
Authors: Comparative characteristics of DNA polymorphisms of �º-casein gene (CSN3) in the horse and donkey
The aims of this study were to assess the genetic variability in the exon 1 of the κ-casein gene in four Italian horse populations (Italian Saddle horse, Italian Trotter, Italian Heavy Draught horse, and Murgese horse) and in a sample of Martina Franca donkey by estimating genotype, allele and haplotype frequencies, as well as several population gen.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.20
- DOI:
- 10.4238/2015.November.18.20
Characterization of HSP70 and its expression in tissue: correlation with physiological and immune indices in goose (Anser cygnoides) serum
Authors: W.W. Zhang, X. Xiao, J.K. Gan, X.Q. Zhang, L.N. Kong and Q.B. Luo
We cloned the goose heat shock protein 70 gene (HSP70), to determine its sequence variation and elucidate its mRNA expression. We designed primers to amplify the entire goose HSP70 sequence. We used 10 commercial Wuzong goslings in a heat-stress experiment. We collected tissue samples for RNA extraction and quantitative real-t.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.9.17
- DOI:
- 10.4238/2015.October.9.17
Allelopathy of the invasive plant Bidens frondosa on the seed germination of Geum japonicum var. chinense
Authors: X.F. Wang, D. Hassani, Z.W. Cheng, C.Y. Wang and J. Wu
Five gradient concentrations (0.02, 0.04, 0.06, 0.08, and 0.10 g/mL) of leaching liquors from the roots, stems, and leaves of the invasive plant Bidens frondosa were used as conditioning fluid to examine its influence on seed germination conditions of the native plant Geum japonicum var. chinense in Huangshan. All leaching liquors of organs suppressed the.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.December.12.22
- DOI:
- 10.4238/2014.December.12.22
Study of polymorphic variants of the serotonin 2A receptor gene (5-HT2A) and its possible effects on smoking habits of a population from northeastern Brazil
Authors: E.S. Ramos Neto1,2, J.O. M�¡gulas1,2, J.J.S. Sousa 1, A.C.M. Moura1, G.R. Pinto1,2, F.K.N. Yoshioka1,2, R. Canalle1,2 and F.J.N. Motta1,2
Previous studies have revealed a genetic component, including genetic polymorphisms in the serotonergic pathway, particularly in the serotonin receptor gene (5-HT2A). The aim of this study was to investigate associations of the T102C (rs6313) and A-1438G (rs6311) polymorphisms with tobacco use in a population from northeastern Brazil. We evaluated these p.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.October.20.3
- DOI:
- 10.4238/2014.October.20.3
Curative effect and safety of intrathecal transplantation of neural stem cells for the treatment of cerebral hemorrhage
Authors: Y.Z. Xue, X.X. Li, L. Li, S.L. Pang, J.G. Yao and P.L. Hao
In this study, we aimed to explore the curative effect and safety of neural stem cell intrathecal transplantation for the treatment of cerebral hemorrhage. We transplanted 4.0 x 108 neural stem cells per procedure into the subarachnoid space by lumbar puncture 7 days after cerebral hemorrhage, twice a week, a total of 4 times. NIHSS scores and brain CT sc.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.October.20.5
- DOI:
- 10.4238/2014.October.20.5
Combination of high-intensity focused ultrasound irradiation and hydroxyapatite nanoparticle injection to injure normal goat liver tissue in vivo without costal bone incision
Authors: L. Liu1, Z. Xiao1, Y. Xiao1, Z. Wang2, F. Li2, M. Li1 and X. Peng1
The aims of this study were to evaluate the in vivo safety of intravenous nano-hydroxyapatite (nano-HA), to explore how nano-HA might influence the effects of high-intensity focused ultrasound (HIFU) on normal liver tissue, and to investigate whether intravenous nano-HA could enhance HIFU for hepatocellular carcinoma ablation in a goat model... Read More»
- Genet. Mol. Res. 13(4):
- 2014.October.20.6
- DOI:
- 10.4238/2014.October.20.6