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Genetic diversity of polysporic isolates of Moniliophthora perniciosa (Tricholomataceae)
Authors: L.F.R. Ferreira, K.M.R. Duarte, L.H. Gomes, R.S. Carvalho, G.A. Leal Junior, M.M. Aguiar, R.D. Armas and F.C.A. Tavares
The causal agent of witches’ broom disease, Moniliophthora perniciosa is a hemibiotrophic and endemic fungus of the Amazon basin and the most important cocoa disease in Brazil. The purpose of this study was to analyze the genetic diversity of polysporic isolates of M. perniciosa to evaluate the adaptation of the pathogen from different Brazilian reg.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.July.10.11
- DOI:
- 10.4238/2012.July.10.11
Cloning, sequence characterization, and expression patterns of members of the porcine TSSK family
Authors: P. Wang, H.L. Huo, S.Y. Wang, Y.W. Miao, Y.Y. Zhang, Q.L. Zhang, F.Q. Li, L.X. Liu, W.Z. Li, Y.Z. Zeng, J.L. Huo and H. Xiao
Testis-specific serine kinases (TSSKs) are a family of serine/threonine kinases highly expressed in the testes that are responsible for regulating many spermatogenesis-related protein activities. Mutations in this family have a positive relationship with oligospermia and azoospermia in human and mouse. Here, five members of th.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.18.56
- DOI:
- 10.4238/2015.October.18.56
Genetic association of productive and reproductive traits with stayability in Nellore cattle: analysis using Bayesian models
Authors: E.C.A. Rizzo, F.R.A. Neto, I.D.P.S. Diaz, M.M. Dias, R.B. Costa, H.T. Ventura, H.N. Oliveira and A.J.S. Falc�£o
We evaluated the genetic association of growth traits [weight adjusted to 205 days of age (W205), 365 days of age (W365), and 550 days of age (W550); weight gain between 205 days of age and 365 days of age (WG1) and between 365 days of age and 550 days of age (WG2)] and reproductive traits [age at first calving (AFC); first ca.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.24.3
- DOI:
- 10.4238/2015.November.24.3
Molecular cloning, polymorphisms, and expression analysis of the RERG gene in indigenous Chinese goats
Authors: M.X. Sui, H.H. Wang and Z.W. Wang
The current study aimed to investigate the coding sequence, polymorphisms, and expression of the RERG gene in indigenous Chinese goats. cDNA of RERG, obtained through reverse transcription PCR was analyzed using bioinformatic techniques. Polymorphisms in the exon regions of the RERG gene were identified and their associations .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.24.1
- DOI:
- 10.4238/2015.November.24.1
Mapping of HtNB, a gene conferring non-lesion resistance before heading to Exserohilum turcicum (Pass.), in a maize inbred line derived from the Indonesian variety Bramadi
Authors: H. Wang, Z.X. Xiao, F.G. Wang, Y.N. Xiao, J.R. Zhao, Y.L. Zheng and F.Z. Qiu
The gene HtNB confers non-lesion resistance to the fungal pathogen Exserohilum turcicum in maize. To map this gene, we developed two F2 populations, P111 (resistant line) x HuangZao 4 (susceptible line) and P111 x B73 (susceptible). HtNB was located on chromosome 8.07 bin, flanked by MAC216826-4 and umc2218 at distances of 3.3 and 3.4 cM, respectively. Ht.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.July.10.7
- DOI:
- 10.4238/2012.July.10.7
Multidrug resistance gene (MDR1) polymorphisms may not be directly associated with response to imatinib in chronic myeloid leukemia
Authors: J.L. Wang, H.J. Liu, F. Li, W.Y. Yang, J.M. Wang, S.F. Tan and Q. Wang
Our study aimed to investigate the association between multidrug resistance (MDR1) gene polymorphisms and the response to imatinib (IM) in chronic myeloid leukemia (CML). An electronic databases in PubMed, Cochrane Library, Wanfang, China National Knowledge Infrastructure, and VIP were searched using combinations of k.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.24.4
- DOI:
- 10.4238/2015.November.24.4
Targeting exogenous GDNF gene to the bovine somatic cell beta-casein locus for the production of transgenic bovine animals
Authors: X.M. Zhang, F.H. Luo, H.M. Ding, B. Li, J.J. Zhang and Y.J. Wu
Considerable attention is currently being directed toward methods for producing recombinant human proteins in the mammary glands of genetically modified transgenic livestock. However, the expression of inserted genes in transgenic animals is variable and often very low because of the randomness of the site of transgene integra.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.24.6
- DOI:
- 10.4238/2015.November.24.6
Phylogenetic diversity of endophytic leaf fungus isolates from the medicinal tree Trichilia elegans (Meliaceae)
Authors: S.A. Rhoden, A. Garcia, C.J. Rubin Filho, J.L. Azevedo and J.A. Pamphile
Various types of organisms, mainly fungi and bacteria, live within vegetal organs and tissues, without causing damage to the plant. These microorganisms, which are called endophytes, can be useful for biological control and plant growth promotion; bioactive compounds from these organisms may have medical and pharmaceutical applications. Trichilia elegans .. Read More»
- Genet. Mol. Res. 11(3):
- 2012.June.15.8
- DOI:
- 10.4238/2012.June.15.8
Cultivar identification and genetic relationship of pineapple (Ananas comosus) cultivars using SSR markers
Authors: Y.S. Lin, C.S. Kuan, I.S. Weng and C.C. Tsai
The genetic relationships among 27 pineapple [Ananas comosus (L.) Merr.] cultivars and lines were examined using 16 simple sequence repeat (SSR) markers. The number of alleles per locus of the SSR markers ranged from 2 to 6 (average 3.19), for a total of 51 alleles. Similarity coefficients were calculated on the basis.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.24.11
- DOI:
- 10.4238/2015.November.24.11
Effects of kinase insert domain receptor (KDR) gene silencing on the sensitivity of A549 cells to erlotinib
Authors: W.L. Zhu and Y.H. Liu
We investigated the effects of kinase insert domain receptor (KDR) gene silencing on the proliferation of A549 cells and their sensitivity to erlotinib. A KDR small interfering RNA (siRNA) sequence was designed and synthesized; then, it was transfected into A549 cells using LipofectamineTM 2000. KDR mRNA and protein expression after KDR gene si.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.24.15
- DOI:
- 10.4238/2015.November.24.15