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Molecular and biochemical characterization of the effects of insecticidal toxin from meloidae beetles on Helicoverpa armigera (Hub.) (Lepidoptera: Noctuidae)
Authors: R.A. Khan1, M. Rashid1, D. Wang2 and Y.L. Zhang1
The molecular and biochemical effects of an insecticidal toxin extracted from Meloidae beetles were investigated on Helicoverpa armigera. The toxin was identified as cantharidin, a well-known natural compound produced by beetles of family Meloidae and Oedemeridae. Furthermore, the effect of the toxin on the metabolic enzymes alkaline phosphatase (ALP) and.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.10.5
- DOI:
- 10.4238/2013.October.10.5
Expression of heat shock protein 90 alpha (Hsp90�±) in primary neonatal rat myocardial cells exposed to various periods of heat stress in vitro
Authors: A. Islam, B. Rehana, M. Zhang, Z.J. Liu, S. Tang, J. Hartung and E.D. Bao
The objective of this study was to investigate the mechanism of heat shock protein 90 alpha (Hsp90α) protection against heart damage resulting from heat stress by detecting Hsp90α mRNA, Hsp90α protein, protein localization, and cell damage in primary myocardial cells of neonatal rats in response to heat stres.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.14.9
- DOI:
- 10.4238/2014.April.14.9
Association of BRCA2 variants with cardiovascular disease in Saudi Arabia
Authors: M. Alanazi, N.P. Reddy, J.P. Shaik, S.A. Ajaj, A.A.A. Jafari, H. Saeed, Z. Khan and A.P. Khan
Abnormalities in the breast cancer tumor suppressor genes (BRCA1 and BRCA2) are associated with breast and ovarian cancer. Recently, two single nucleotide polymorphisms (SNPs; rs11571836 and rs1799943) were identified, both located in untranslated regions of chromosome 13, associated with cardiovascular disease (CVD) in a mult.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.16.13
- DOI:
- http://dx.doi.org/10.4238/2014.May.16.13
Development of microsatellite markers for the kelp grouper Epinephelus bruneus by 454 pyrosequencing and transfer to related species
Authors: J.-H. Kang1, S.G. Yang2, T.S. Moon2, J.-Y. Park1 and T.-J. Choi3
The kelp or longtooth grouper (Epinephelus bruneus), which inhabits Eastern Asia, is the most economically important of 11 grouper species that inhabit the Southern Sea near Jeju Island in Korea. This species is listed as vulnerable by the International Union for the Conservation of Nature and Natural Resources because of a rapid decrease in its resources.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.13.1
- DOI:
- 10.4238/2013.November.13.1
Expression profile analysis reveals putative prostate cancer-related microRNAs
Authors: H. Song1*, Y. Liu2*, J. Pan3 and S.T. Zhao1
Annotation of prostate cancer (PC) genomes provides a foundation for discoveries that can improve the understanding and treatment of the disease. Therefore, in the present study, we used the Student t-test to identify differentially expressed PC-related mRNAs and microRNAs (miRNAs). Then, we performed interrelated mapping of miRNA target genes between abn.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.24.4
- DOI:
- 10.4238/2013.October.24.4
Novel association analysis between HLA-DQB1 polymorphisms and rectal cancer based on a cross-validation design
Authors: F.Z. Tong, W.J. Yu, H. Liu
A new study design based on cross-validation of the age at the onset of rectal cancer and the differences between the frequency distributions of relevant genes in 2 groups was developed for identification of disease-related HLA. Patients with rectal cancer were recruited and their age at the time of the first surgery was recor.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.26.5
- DOI:
- 10.4238/2013.November.26.5
Relationship between dilated cardiomyopathy and the E23K and I337V polymorphisms in the Kir6.2 subunit of the KATP channel
Authors: H.L. Xi1*, J.F. Liu1*, L. Li2 and J. Wan1
ATP-sensitive potassium channels play an important role in myocardial electrical activity. Genetic disruption of these channels predisposes the myocardium to cardiac diseases. Herein we investigated whether two polymorphisms, E23K and I337V, located in the Kir6.2 subunit of ATP-sensitive potassium channels are associated with dilated cardiomyopathy (DCM) .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.10.4
- DOI:
- 10.4238/2013.October.10.4
Identification of orchardgrass (Dactylis glomerata L.) cultivars by using simple sequence repeat markers
Authors: L.-F. Jiang1, X.-Q. Zhang1, X. Ma1, L.-K. Huang1, W.-G. Xie2, Y.-M. Ma1 and Y.-F. Zhao1
The accurate identification of orchardgrass (Dactylis glomerata L.) cultivars is necessary to ensure purity for consumers, the effective utilization of cultivars, and to protect the intellectual property for breeders. Therefore, this study aimed to use SSR to construct DNA fingerprinting of orchardgrass cultivars. The genetic diversity of 32 orchardgrass .. Read More»
- Genet. Mol. Res. 12(4):
Relationship between the acylation-stimulating protein gene and coronary heart disease in the Xinjiang Uygur and Han populations of China
Authors: Y. Chen, Y.T. Ma, S.J. Yang, Y.N. Yang, Z.Y. Fu, X. Xie, X.M. Li and Y.Y. Zheng
The association of the single nucleotide polymorphism 301T>C in the coding region of the acylation-stimulating protein (ASP) gene with coronary heart disease (CHD) was investigated in the Uygur (385 CHD patients and 483 control subjects) and Han (390 CHD patients and 439 control subjects) populations of China. The frequency.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.8.6
- DOI:
- 10.4238/2014.April.8.6
Mendelian inheritance, genetic linkage, and genotypic disequilibrium at nine microsatellite loci of Cariniana legalis (Mart.) O. Kuntze
Authors: E.V. Tambarussi1, R. Vencovsky1, M.L.M. Freitas2 and A.M. Sebbenn3
Cariniana legalis is one of the largest tropical trees with a wide distribution in the Brazilian Atlantic rainforest. We investigated the Mendelian inheritance, genetic linkage, and genotypic disequilibrium at seven microsatellite loci specifically isolated for C. legalis, and at two previously developed heterologous microsatellite loci. Forty to 100 open.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.11.6
- DOI:
- 10.4238/2013.November.11.6