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An I/O device driver for bioinformatics tools: the case for BLAST
Authors: Renato Campos Mauro and S�©rgio Lifschitz
There are many bioinformatics tools that deal with input/ output (I/O) issues by using filing systems from the most common operating systems, such as Linux or MS Windows. However, as data volumes increase, there is a need for more efficient disk access, ad hoc memory management and specific page-replacement policies. We propos.. Read More»
- Genet. Mol. Res. 4(3):
Genomic changes at the early stage of somatic hybridization
Authors: Y. Sun, C.H. Xu, M.Q. Wang, D.Y. Zhi and G.M. Xia
A broad spectrum of genetic and epigenetic changes is induced by wide hybridization and subsequent polyploidization, but the timing of these events remains obscure because early hybrid cells are very difficult to harvest and analyze. Here, we used both cytological and genetic marker approaches to analyze the constitution of very young somatic hybrid cells.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.March.17.21
- DOI:
- http://dx.doi.org/10.4238/2014.March.17.21
Identification of significantly different modules between permanent and deciduous teeth by network and pathway analyses
Authors: J. Kang, R. Bai, K. Liu, X.P. Ji, Y. Li and J.Y. Han
The differences in genetic backgrounds between deciduous and permanent teeth might contribute to the differences in developmental processes, histological characteristics, and tooth life cycles. Here, we attempted to identify significantly different modules between permanent and deciduous teeth via network and pathway analyses... Read More»
- Genet. Mol. Res. 15(4):
- gmr15047959
- DOI:
- 10.4238/gmr15047959
Mutual information content of homologous DNA sequences
Authors: Helena Cristina G. Leit�£o, Luciana S. Pess�´a and Jorge Stolfi
The necessary information to reproduce and keep an organism is codified in acid nucleic molecules. Deepening the knowledge about how the information is stored in these bio-sequences can lead to more efficient methods of comparing genomic sequences. In the present study, we analyzed the quantity of information contained in a DN.. Read More»
- Genet. Mol. Res. 4(3):
Modeling of crossbred cattle growth, comparison between cubic and piecewise random regression models
Authors: H.R. Mirzaei, W.S. Pitchford and A.P. Verbyla
Two analyses, cubic and piecewise random regression, were conducted to model growth of crossbred cattle from birth to about two years of age, investigating the ability of a piecewise procedure to fit growth traits without the complications of the cubic model. During a four-year period (1994-1997) of the Australian “South.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1302
- DOI:
- 10.4238/vol10-3gmr1302
Reconfigurable systems for sequence alignment and for general dynamic programming
Authors: Ricardo P. Jacobi, Mauricio Ayala-Rinc�³n, Luis G.A. Carvalho, Carlos H. Llanos and Reiner W. Hartenstein
Reconfigurable systolic arrays can be adapted to efficiently resolve a wide spectrum of computational problems; parallelism is naturally explored in systolic arrays and reconfigurability allows for redefinition of the interconnections and operations even during run time (dynamically). We present a reconfigurable systolic archi.. Read More»
- Genet. Mol. Res. 4(3):
A framework based on Web service orchestration for bioinformatics workflow management
Authors: Luciano A. Digiampietri, Claudia B. Medeiros and Jo�£o C. Setubal
Bioinformatics activities are growing all over the world, with proliferation of data and tools. This brings new challenges: how to understand and organize these resources and how to provide interoperability among tools to achieve a given goal. We defined and implemented a framework to help meet some of these challenges. Four i.. Read More»
- Genet. Mol. Res. 4(3):
A case-control study on the risk factors of urinary calculus in Uyghur children in the Kashi region
Authors: H.C. Wang, C. Liu, H.Y. He and M.X. Wang
The incidence of urinary calculus (UC) is very high in Uyghur children in the Kashi region of Xinjiang, China, which seriously affects the growth and life quality of these children. This study was aimed at investigating the risk factors of UC in Uyghur children in Kashi region. One hundred fifteen Uyghur children (age <7 years) with UC who were treated.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.1.3
- DOI:
- 10.4238/2015.June.1.3
Combining ability of tropical maize lines for seed quality and agronomic traits
Authors: L.M. Moterle, A.L. Braccini, C.A. Scapim, R.J.B. Pinto, L.S.A. Gon�§alves, A.T. do Amaral J�ºnior and T.R.C. Silva
Studies of genetic effects of early selection of maize based on seed quality traits are rare, especially those that use materials from different heterotic groups. These studies are also useful in tropical environments and for the advancement of sustainable agriculture with cropping during seasons not commonly used for cultivat.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1129
- DOI:
- 10.4238/vol10-3gmr1129
Is there any association between childhood cardiac septal defects and ROCK2 gene polymorphism?
Authors: M. Aksoy, H. Uygun, O. Baspinar, S. Demiryurek, S. Oztuzcu,B. Cengiz, A. Irdem and N.C. Araz
Rho/Rho-kinase pathway plays a critical role in the regulation of cellular functions such as proliferation and migration. One of the possible theories of the development of ventricular septal defects is cell migration disorder. The aim of this study was to analyze the genotype distributions and allele frequencies for the ROCK2 gene Thr431Asn polymorphisms.. Read More»
- Genet. Mol. Res. 13(1):