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Human Genetics   Research Article

MtDNA variability in whitefly (Bemisia tabaci) populations in Brazil

Authors: G.E. Valle, A.L. Louren�§�£o, M.I. Zucchi, J.B. Pinheiro and A.G. Abreu

Bemisia tabaci (Hemiptera: Aleyrodidae) consists of a complex of morphologically indistinct biotypes that vary mainly in their capacity to transmit plant viruses and to induce physiological disorders in plants of economic importance. The adaptability of B. tabaci to many regions of the world has fostered the appearance of vari.. Read More»

Genet. Mol. Res. 10(3):
vol10-3gmr1183
DOI:
10.4238/vol10-3gmr1183
Animal Genetics   Research Article

Carcass composition and meat quality of indigenous Yanan pigs of China

Authors: Y.-Z. Jiang, L. Zhu, F.-Q. Li and X.-W. Li

The Yanan (YN) pig is a traditional Chinese indigenous breed that is raised in southwest China in the Sichuan Province, but there is little data on the germplasm characteristics of this breed. To evaluate carcass characteristics and meat quality of the YN pig, we compared carcass and meat quality of YN pigs and Landrace ×.. Read More»

Genet. Mol. Res. 11(1):
http://dx.doi.org/2012.January.27.3
DOI:
http://dx.doi.org/10.4238/2012.January.27.3
Human Genetics   Research Article

HIV TAT variants differentially influence the production of glucocerebrosidase in Sf9 cells

Authors: Andrea K. Vaags, Tessa N. Campbell and Francis Y.M. Choy

Gaucher disease, the most common lysosomal storage disorder, is currently treated with enzyme replacement therapy. This approach, however, is ineffective in altering the progression of neurodegeneration in type 2 and type 3 patients due to the difficulty of transferring the recombinant enzyme across the blood-brain barrier. Hu.. Read More»

Genet. Mol. Res. 4(3):
Animal Genetics   Research Article

Genetic and non-genetic effects on productive and reproductive traits of cows in dual-purpose herds in southeastern Mexico

Authors: G.M. Parra-Bracamonte, J.G. Maga�±a, R. Delgado, M.M. Osorio-Arce and J.C. Segura-Correa

Data on productive and reproductive performance of cows in dual-purpose herds were analyzed to determine the effect of some environmental and genetic factors on saleable milk yield (SMY), lactation length (LL), daily saleable milk per lactation (DMYL), calving interval (CI), and daily saleable milk per calving interval (MYCI) .. Read More»

Genet. Mol. Res. 4(3):
Microbial Genetics   Research Article

Improved thermostable �±-amylase activity of Bacillus amyloliquefaciens by low-energy ion implantation

Authors: X.Y. Li, J.L. Zhang and S.W. Zhu

Thermostable α-amylase is of great importance in the starch fermentation industry; it is extensively used in the manufacture of beverages, baby foods, medicines, and pharmaceuticals. Bacillus amyloliquefaciens produces thermostable α-amylase; however, production of thermostable α-amylase is limited. Ion-beam .. Read More»

Genet. Mol. Res. 10(3):
vol10-3gmr1081
DOI:
10.4238/vol10-3gmr1081
Bioinformatics   Review Article

Gene selection based on multi-class support vector machines and genetic algorithms

Authors: Bruno Feres de Souza and Andr�© Ponce de Leon F. de Carvalho

Microarrays are a new technology that allows biologists to better understand the interactions between diverse pathologic state at the gene level. However, the amount of data generated by these tools becomes problematic, even though data are supposed to be automatically analyzed (e.g., for diagnostic purposes). The issue become.. Read More»

Genet. Mol. Res. 4(3):
Human Genetics   Research Article

Association of eNOS gene polymorphisms with essential hypertension in the Han population in southwestern China

Authors: J. Li, Y. Cun, W.R. Tang, Y. Wang, S.N. Li, H.R. Ouyang, Y.R. Wu, H.J. Yu and C.J. Xiao

Endothelial nitric oxide synthase (eNOS) plays an important role in maintaining blood pressure homeostasis and vascular integrity. Polymorphisms in the eNOS gene have been found to be associated with hypertension in different human populations, including Northern and Southern Chinese Han populations. To examine the relationshi.. Read More»

Genet. Mol. Res. 10(3):
vol10-3gmr1160
DOI:
10.4238/vol10-3gmr1160
Human Genetics   Research Article

Association between dopamine D2 receptor gene polymorphisms and the risk of heroin dependence

Authors: N. Wang1*, J.B. Zhang1*, J. Zhao1, X.T. Cai1, Y.S. Zhu1,2 and S.B. Li1,2

Heroin dependence is a chronic relapsing brain disease. Researchers have reported that the dopamine D2 receptor (DRD2) is involved in the development of opiate dependence. To identify markers that contribute to the genetic susceptibility to heroin addiction, we examined the potential association between heroin dependence and s.. Read More»

Genet. Mol. Res. 15(4):
http://dx.doi.org/gmr15048772
DOI:
http://dx.doi.org/10.4238/gmr15048772
Bioinformatics   Review Article

An agent-based system for re-annotation of genomes

Authors: Leonardo Vianna do Nascimento and Ana L.C. Bazzan

Genome annotation projects can produce incorrect results if they are based on obsolete data or inappropriate models. We have developed an automatic re-annotation system that uses agents to perform repetitive tasks and reports the results to the user. These tasks involve BLAST searches on biological databases (GenBank) and the .. Read More»

Genet. Mol. Res. 4(3):
Human Genetics   Research Article

Frequency distribution of interleukin-10 haplotypes (-1082 A>G, -819 C>T, and-592 C>A) in a Mexican population

Authors: M. V�¡zquez-Villamar, C.A. Palafox-S�¡nchez, J. Hern�¡ndez-Bello,J.F. Mu�±oz-Valle, Y. Valle, A. Cruz, A.I. Alatorre-Meza and E. Oregon-Romero

Interleukin 10 (IL-10) is an immunoregulatory cytokine with multiple roles in the immune system. Three single nucleotide polymorphisms at positions -1082 (A>G), -819 (C>T), and -592 (C>A) in the promoter region of the IL10 gene are believed to be associated with different inflammatory, infectious, and autoimmune disea.. Read More»

Genet. Mol. Res. 15(4):
gmr15048411
DOI:
10.4238/gmr15048411