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Plant Genetics   Research Article

Genetic potential of black bean genotypes with predictable behaviors in multienvironment trials

Authors: P.P. Torga, P.G.S. Melo, H.S. Pereira, L.C. Faria and L.C. Melo

The aim of this study was to evaluate the phenotypic stability and specific and broad adaptability of common black bean genotypes for the Central and Center-South regions of Brazil by using the Annicchiarico and AMMI (weighted average of absolute scores: WAAS, and weighted average of absolute scores and productivity: WAASP) me.. Read More»

Genet. Mol. Res. 15(4):
gmr15049029
DOI:
10.4238/gmr15049029
Bioinformatics   Research Article

Mining ORESTES no-match database: can we still contribute to cancer transcriptome?

Authors: Rog?©rio da Silva Fonseca, Dirce Maria Carraro and Helena Brentani

The Human Cancer Genome Project generated about 1 million expressed sequence tags by the ORESTES method, principally with the aim of obtaining data from cancer. Of this total, 341,680 showed no similarity with sequences in the public transcript databases, referred to as “no-match”. Some of them represent low abunda.. Read More»

Genet. Mol. Res. 5(1):
Animal Genetics   Research Article

Ion-exchange chromatography used to isolate a spermadhesin-related protein from domestic goat (Capra hircus) seminal plasma

Authors: D?¡rcio ?talo Alves Teixeira, Luciana Magalh?£es Melo, Carlos Alberto de Almeida Gadelha, Rodrigo Maranguape Silva da Cunha, Carlos Bloch Jr., Gandhi R?¡dis-Baptista, Benildo Sousa Cavada and Vicente Jos?© de Figueir?ªdo Freitas

Mammalian seminal plasma contains among others, proteins called spermadhesins, which are the major proteins of boar and stallion seminal plasma. These proteins appear to be involved in capacitation and sperm-egg interaction. Previously, we reported the presence of a protein related to spermadhesins in goat seminal plasma. In t.. Read More»

Genet. Mol. Res. 5(1):
Plant Genetics   Research Article

Identification of the transcriptionally active cytochrome P450 repertoire in Coffea arabica

Authors: S.T. Ivamoto, D.S. Domingues, L.G.E. Vieira and L.F.P. Pereira

Cytochrome P450s (P450s) comprise a gene superfamily encoding enzymes that are involved in diverse plant metabolic pathways that produce primary and secondary metabolites such as phenylpropanoids, terpenoids, nitrogen-containing compounds, and plant hormones. They comprise one of the most diverse gene families in plant evolution. Although there are many s.. Read More»

Genet. Mol. Res. 14(1):
http://dx.doi.org/2015.March.27.25
DOI:
http://dx.doi.org/10.4238/2015.March.27.25
Plant Genetics   Research Article

Plant microsatellite genotyping with 4-color fluorescent detection using multiple-tailed primers

Authors: Alexandre Missiaggia and Dario Grattapaglia

We extended the concept of fluorescent microsatellite genotyping with a single-universal tailed primer to the simultaneous use of three different tailed primers to allow multiplexed 4-color detection for medium throughput genotyping of plant species. The method was tested on Eucalyptus DNA samples using three forward primer se.. Read More»

Genet. Mol. Res. 5(1):
Medical Genetics   Review Article

The time has come: a new scene for PKU treatment

Authors: Luciana Lara dos Santos, Myrian de Castro Magalh?£es, Jos?© N?©lio Janu?¡rio, Marcos Jos?© Burle de Aguiar and Maria Raquel Santos Carvalho

Phenylketonuria (PKU) is one of the few genetic diseases in which mental retardation can be prevented. Hence, diagnosis and treatment must be established early. PKU treatment consists of a phenylalanine-restricted diet supplemented with a phenylalanine-free mixture of amino acids. However, it is difficult to adhere to this die.. Read More»

Genet. Mol. Res. 5(1):
Animal Genetics   Research Article

Well-balanced commensal microbiota contributes to anti-cancer response in a lung cancer mouse model

Authors: Q.-F. Gui, H.-F. Lu, C.-X. Zhang, Z.-R. Xu and Y.-M. Yang

The intestinal microflora affects inflammation and immunity, not only locally at the mucosal level but also systemically, raising the question of whether the microflora affects inflammatory processes that contribute to cancer and its therapy. Prebiotics have also been found to play an antitumor role that is not limited to the gut. We investigated the anti.. Read More»

Genet. Mol. Res. 14(2):
2015.May.25.16
DOI:
10.4238/2015.May.25.16
Medical Genetics   Research Article

Frequencies of phenylalanine hydroxylase mutations I65T, R252W, R261Q, R261X, IVS10nt11, V388M, R408W, Y414C, and IVS12nt1 in Minas Gerais, Brazil

Authors: Luciana Lara dos Santos, Myrian de Castro Magalh?£es, Adriana de Oliveira Reis, Ana L?ºcia Pimenta Starling, Jos?© N?©lio Janu?¡rio, Cleusa Gra?§a da Fonseca, Marcos Jos?© Burle de Aguiar and Maria Raquel Santos Carvalho

In order to determine the phenylketonuria (PKU) mutation spectrum in the population of Minas Gerais State, Brazil, 78 unrelated PKU patients found by the neonatal screening program from 1993 to 2003 were tested for nine phenylalanine hydroxylase mutations. These mutations were selected due to their high frequencies in other Br.. Read More»

Genet. Mol. Res. 5(1):
Plant Genetics   Research Article

Effect of ethyl methyl sulfonate concentration and different treatment conditions on germination and seedling growth of the cucumber cultivar Chinese long (9930)

Authors: S.N.M. Shah, Z.-H. Gong, M.H. Arisha, A. Khan and S.-L. Tian

We attempted to create a new germplasm of cucumber cultivar Chinese long (9930) using different doses of ethyl methyl sulfonate (EMS) to induce variability. We tested EMS concentration (0, 0.5, 1.0, 1.5, 2, 3% v/v) with post-treatment (0.1 M Na2S2O3 and water), EMS concentration (0, 0.5, 1.0, 1.5% v/v) over different treatment times (8, 16, 24 h), and EMS.. Read More»

Genet. Mol. Res. 14(1):
http://dx.doi.org/2015.March.30.2
DOI:
http://dx.doi.org/10.4238/2015.March.30.2
Plant Genetics   Research Article

Genetic diversity and population structure of Eucommia ulmoides Oliver, an endangered medicinal plant in China

Authors: J. Yu, Y. Wang, L. Peng, M. Ru and Z.S. Liang

Eucommia ulmoides Oliver, one of the tertiary relict species found only in China, is the only extant species of Eucommiaceae. Using inter-simple sequence repeat (ISSR) and sequence-related amplified polymorphism (SRAP) markers, we studied the genetic diversity and population genetic structure of 187 accessions from 17 E. ulmoides populations throughout it.. Read More»

Genet. Mol. Res. 14(1):
http://dx.doi.org/2015.March.30.5
DOI:
http://dx.doi.org/10.4238/2015.March.30.5