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Human Genetics   Research Article

Increased gene coverage and Alu frequency in large linkage disequilibrium blocks of the human genome

Authors: Y. Wang, P.Y. Fong, F.C.C. Leung, W. Mak and P.C. Sham

The human genome has linkage disequilibrium (LD) blocks, within which single-nucleotide polymorphisms show strong association with each other. We examined data from the International HapMap Project to define LD blocks and to detect DNA sequence features inside of them. We used permutation tests to determine the empirical signi.. Read More»

Genet. Mol. Res. 6(4):
Plant Genetics   Abstracts

Gene expression and nutrient utilization in the basideomycete Moniliophthora perniciosa suggest the existence of regulatory mechanisms of catabolite repression

Authors: I.S. Ganda

Genet. Mol. Res. 9(3):
vol9-3ta033
DOI:
10.4238/vol9-3ta033
Microbial Genetics   Research Article

Sequence analysis of the PIP5K locus in Eimeria maxima provides further evidence for eimerian genome plasticity and segmental organization

Authors: B.K. Song, M.Z. Pan, Y.L. Lau and K.L. Wan

Commercial flocks infected by Eimeria species parasites, including Eimeria maxima, have an increased risk of developing clinical or subclinical coccidiosis; an intestinal enteritis associated with increased mortality rates in poultry. Currently, infection control is largely based on chemotherapy or live vacci.. Read More»

Genet. Mol. Res. 13(3):
2014.July.29.8
DOI:
10.4238/2014.July.29.8
Plant Genetics   Research Article

Microsporogenesis in sexual Brachiaria hybrids (Poaceae)

Authors: V.A. Fuzinatto, M.S. Pagliarini and C.B. Valle

Three sexual interspecific hybrids of Brachiaria (HBGC076, HBGC009, and HBGC014) resulting from crosses between B. ruziziensis (female genitor) and B. decumbens and B. brizantha (male genitors) produced by Embrapa Beef Cattle in the 1980s were cytologically analyzed by conventional methods for meiotic studies. The cytogenetic .. Read More»

Genet. Mol. Res. 6(4):
Plant Genetics   Research Article

Genetic diversity of wild soybean populations in Dongying, China, by simple sequence repeat analysis

Authors: Y.H. Wang, X.J. Zhang and S.J. Fan

Annual wild soybean (Glycine soja Sieb. et Zucc.), the ancestor of cultivated soybean (G. max), is believed to be a potential gene source for further improvement of soybean to cope with environmental stress. In this study, 10 simple sequence repeat (SSR) markers were used to evaluate the genetic diversity and population genetic structure in five wild soyb.. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.28.13
DOI:
http://dx.doi.org/10.4238/2015.September.28.13
Plant Genetics   Research Article

Evaluation of five protocols for DNA extraction from leaves of Malus sieversii, Vitis vinifera, and Armeniaca vulgaris

Authors: K. Aubakirova1,2, M. Omasheva1, N. Ryabushkina1, T. Tazhibaev2,G. Kampitova2 and N. Galiakparov1

Leaves of Malus sieversii, Vitis vinifera, and Armeniaca vulgaris contain substantial amounts of secondary metabolites, which limit the high-quality DNA extraction performance. In this study, five extraction protocols were compared for their ability to produce good quality DNA from fresh and dried (with silica gel) leaves of t.. Read More»

Genet. Mol. Res. 13(1):
http://dx.doi.org/2014.February.27.13
DOI:
http://dx.doi.org/10.4238/2014.February.27.13
Human Genetics   Research Article

Genetic analysis of STR markers on chromosome 21 in a Han population from southeast China

Authors: Y.N. Zhu, S.M. Lu, M. Wang, F.X. Shen, Y. Chen and J.J. Hu

Short tandem repeats (STRs) are highly polymorphic sequences and have been extensively used as genetic markers in mapping studies, disease diagnosis, and human identity testing. In this study, 11 STR markers on chromosome 21, including D21S1432, D21S11, D21S1246, D21S1412, D21S1437, D21S1442, D21S2039, D21S1270, D21S1435, D21S1409, and D21S1446, were anal.. Read More»

Genet. Mol. Res. 14(1):
2015.March.6.18
DOI:
10.4238/2015.March.6.18
Human Genetics   Research Article

Clinical value of fluid bolus contrast flow meter during hysterosalpingography

Authors: Y.P. Ji, Y. Xu, S.Z. Xia, F.Y. Bian, H. Zhang and G.H. Shen

The purpose of this study was to investigate the clinical value of the fluid bolus contrast flow meter during hysterosalpingography. Hysterosalpingography information of 342 cases, which included a manual handset group of 213 cases and a bolus instrument group of 129 cases were reviewed. Comparative analysis was used to compare the two groups in order to .. Read More»

Genet. Mol. Res. 14(1):
2015.March.6.19
DOI:
10.4238/2015.March.6.19
Human Genetics   Research Article

Mechanism of the reversal effect of mifepristone on drug resistance of the human cervical cancer cell line HeLa/MMC

Authors: H. Chen, J. Duan and F. Zuo

We examined the ability of mifepristone to reverse the in vitro drug resistance of human cervical cancer cells resistant to mitomycin-C (HeLa/MMC) cells and investigated the mechanism of this effect. A 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay was performed to detect the drug resistance of HeLa/MMC cel.. Read More»

Genet. Mol. Res. 13(1):
http://dx.doi.org/2014.February.27.14
DOI:
http://dx.doi.org/10.4238/2014.February.27.14
Animal Genetics   Research Article

Genetic parameters for earnings in Quarter Horse

Authors: A.P.A. Silva, R.A. Curi, B. Langlois and J.A.II.V. Silva

In this study, we estimated the heritability (h2) of earnings in the Quarter Horse in order to evaluate the inclusion of this trait in breeding programs. Records from 14,754 races of 2443 horses from 1978-2009 were provided by Sorocaba Hippodrome, São Paulo, Brazil. All ancestors of the registered horses were included i.. Read More»

Genet. Mol. Res. 13(3):
2014.August.1.2
DOI:
10.4238/2014.August.1.2