Se
Function Clustering Self-Organization Maps (FCSOMs) for mining differentially expressed genes in Drosophila and its correlation with the growth medium
Authors: L.L. Liu, M.J. Liu and M. Ma
The central task of this study was to mine the gene-to-medium relationship. Adequate knowledge of this relationship could potentially improve the accuracy of differentially expressed gene mining. One of the approaches to differentially expressed gene mining uses conventional clustering algorithms to identify the gene-to-medium relationship. Compared to co.. Read More»
- Genet. Mol. Res. 14(3):
- DOI http://dx.doi.org/2015.September.28.18
- DOI:
- DOI http://dx.doi.org/10.4238/2015.September.28.18
Identification of critical TF-miRNA-mRNA regulation loops for colorectal cancer metastasis.
Authors: C. Wang, D.Z. Hu and J.Z. Liu
To explore the potential cause of colorectal cancer metastasis, gene expression profiles, GSE21510, and miRNA expression profiles, GSE48074, were downloaded from the Gene Expression Omnibus database. Differentially expressed genes in metastatic colorectal and non metastatic colorectal cancer compared with the normal samples were identified via the limma p.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.22.19
- DOI:
- 10.4238/2015.May.22.19
No association of polymorphisms in the suppressor of cytokine signaling (SOCS)-3 with rheumatoid arthritis in the Chinese Han population
Authors: L.P. Sun*, X.L. Ma*, H.X. Liu, Y.S. Wang and X.F. Li
Suppressor of cytokine signaling (SOCS)-3 is a key negative regulator of cytokine signaling that inhibits the JAK/STAT signal transduction pathway; there are reports describing its role in attenuating arthritis through SOCS-3 overexpression. We examined the relationship between polymorphisms in the coding sequence and promoter.. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr914
- DOI:
- 10.4238/vol9-3gmr914
Cross-leg repair of large soft-tissue defects in distal sites of the feet by distally based neuro-fasciocutaneous flaps with perforating vessels
Authors: Z.Q. Wang, Y.L. Cao, Y.F. Huang, D.Q. Liu and X.F. Li
The objective of this study was to introduce a method for repairing large soft-tissue defects on the foot. Distally based neuro-fasciocutaneous flaps with perforating vessels were designed along the saphenous and sural neurovascular axes. The cutaneous perforating branches of the major arteries of the lower extremities were us.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.25.1
- DOI:
- 10.4238/2014.July.25.1
Identification of critical TF-miRNA-mRNA regulation loops for colorectal cancer metastasis
Authors: C. Wang D.Z. Hu and J.Z. Liu
To explore the potential cause of colorectal cancer metastasis, gene expression profiles, GSE21510, and miRNA expression profiles, GSE48074, were downloaded from the Gene Expression Omnibus database. Differentially expressed genes in metastatic colorectal and non metastatic colorectal cancer compared with the normal samples were identified via the limma p.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.22.19
- DOI:
- 10.4238/2015.May.22.19
Anastomosis groups and molecular variation in Pseudocercospora griseola
Authors: K.J. Damasceno-Silva, E.A. Souza, C.N.S. Freire and F.H. Ishikawa
The fungus Pseudocercospora griseola is the causal agent of angular leaf spot, a common bean (Phaseolus vulgaris L.) disease. The successful development of angular leaf spot-resistant cultivars depends on understanding the levels of variability in pathogen populations. P. griseola shows great pathogenic and genetic variation using inoculation on different.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.3.19
- DOI:
- 10.4238/2015.July.3.19
Potential of hypocotyl diameter in family selection aiming at plant architecture improvement of common bean
Authors: A.M.C. Oliveira, R.O. Batista, P.C.S. Carneiro, J.E.S. Carneiro and C.D. Cruz
Cultivars of common bean with more erect plant architecture and greater tolerance to degree of lodging are required by producers. Thus, to evaluate the potential of hypocotyl diameter (HD) in family selection for plant architecture improvement of common bean, the HDs of 32 F2 plants were measured in 3 distinct populations, and the characteristics related .. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.28.3
- DOI:
- http://dx.doi.org/10.4238/2015.September.28.3
Ulinastatin promotes T lymphocyte apoptosis in rats with severe acute pancreatitis via mitochondrial pathways
Authors: C.L. Wang, N. Li, T. Ma, P. Zhang and S.Y. You
We explored the influence of ulinastatin on apoptosis of T lymphocytes in rats with severe acute pancreatitis (SAP) and the effect of ulinastatin on mitochondrial apoptosis pathways in spleen lymphocytes. Thirty-six Wistar rats were randomly divided into three groups (N = 12): a sham operated group, a SAP group, and an ulinastatin-treated SAP group. The S.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.25.2
- DOI:
- 10.4238/2015.May.25.2
Effects of isoflurane preconditioning in the delayed phase on myocardial tumor necrosis factor alpha levels and caspase-3 protein expression in a rabbit model of ischemia-reperfusion injury
Authors: K. Ran, D.Q. Zou, Y.Y. Xiao, Y.T. Chang, K.M. Duan , Y.W. Ou and Z.J. Li
This study aimed to investigate the protective effects and the mechanisms underlying these effects of isoflurane preconditioning in the delayed phase of myocardial ischemia-reperfusion injury. We randomly divided 30 healthy male New Zealand white rabbits into three groups with 10 rabbits in each group as follows: sham operation group (C group), ischemia-r.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.3.1
- DOI:
- 10.4238/2015.July.3.1
Decreased expression of humanized Fat-1 in porcine fetal fibroblasts following deletion of PGK-neomycin resistance
Authors: X.J. Han, H. Liang, T. Yun, Y.H. Zhao, M.L. Zhang, L.H. Zhao, R.F. Li and X.L. Li
The neomycin-resistance (neor) gene is widely used as a selectable marker in eukaryotic expression vectors; however, its expression often affects that of target genes. Cre recombinase recognizes LoxP sites, leading to site-specific recombination and deletion of DNA and RNA between two LoxP sites. In the present study, a humanized Fat-1 gene (hFat-1) was g.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.28.11
- DOI:
- http://dx.doi.org/10.4238/2015.September.28.11