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Apoptosis induced by lipid-associated membrane proteins from Mycoplasma hyopneumoniae in a porcine lung epithelial cell line with the involvement of caspase 3 and the MAPK pathway
Authors: B. Ni, F.F. Bai, Y. Wei, M.J. Liu, Z.X. Feng, Q.Y. Xiong, L.Z. Hua and G.Q. Shao
Lipid-associated membrane proteins (LAMPs) are important in the pathogenicity of the Mycoplasma genus of bacteria. We investigated whether Mycoplasma hyopneumoniae LAMPs have pathogenic potential by inducing apoptosis in a St. Jude porcine lung epithelial cell line (SJPL). LAMPs from a pathogenic strain of M. hyopneumoniae (strain 232) were used in the re.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.25.10
- DOI:
- http://dx.doi.org/10.4238/2015.September.25.10
Genetic diversity of chickpea (Cicer arietinum L.) germplasm in Pakistan as revealed by RAPD analysis
Authors: F. Ahmad, A.I. Khan, F.S. Awan, B. Sadia, H.A. Sadaqat and S. Bahadur
Genetic diversity analysis of chickpea germplasm can provide practical information for the selection of parental material and thus assist in planning breeding strategies. Chickpea seed is a good source of carbohydrates and proteins, constituting 80% of the total dry seed weight. Released cultivars and advanced lines of 30 chic.. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr862
- DOI:
- 10.4238/vol9-3gmr862
Polymorphisms of +2836 G>A in the apoE gene are strongly associated with the susceptibility to essential hypertension in the Chinese Hui population
Authors: Y. Yang, J.R. Xu, X.M. Liu, J. Zhou, B. Yang, M. Li and Y.J. Wang,
In the present study, the correlation of polymorphisms of the apolipoprotein E (apoE) gene with the susceptibility of essential hypertension (EH) was investigated. Single nucleotide polymorphisms of the apoE gene at the -491 A>T, +969 C>G, and +2836 G>A sites were determined in 221 non-EH individuals and 109 subjects .. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.February.27.6
- DOI:
- http://dx.doi.org/10.4238/2014.February.27.6
Molecular evolution of two consecutive carotenoid cleavage dioxygenase genes in strigolactone biosynthesis in plants
Authors: R.K. Wang, J.J. Lu, G.N. Xing, J.Y. Gai and T.J. Zhao
Strigolactones are newly discovered plant hormones that perform various functions, from signaling in symbiotic interactions with arbuscular mycorrhizal fungi to controlling outgrowth of axillary buds. We examined the phylogenetic relationships of two carotenoid cleavage dioxygenase genes (CCD7 and CCD8) that are involved in co.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.2.2
- DOI:
- 10.4238/2011.December.2.2
Genetic diversity of sea-island cotton (Gossypium barbadense) revealed by mapped SSRs
Authors: X.Q. Wang, C.H. Feng, Z.X. Lin and X.L. Zhang
In order to evaluate the genetic diversity of sea-island cotton (Gossypium barbadense), 237 commonly mapped SSR markers covering the cotton genome were used to genotype 56 sea-island cotton accessions. A total of 218 polymorphic primer pairs (91.98%) amplified 361 loci, with a mean of 1.66 loci. Polymorphism information conten.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.8.5
- DOI:
- 10.4238/2011.December.8.5
Influence of glutathione S-transferase polymorphisms on type-2 diabetes mellitus risk
Authors: M.A. Amer, M.H. Ghattas, D.M. Abo-ElMatty and S.H. Abou-El-Ela
Glutathione S-transferase (GST) protects cells against oxidative stress. We evaluated the effect of genetic polymorphisms of the GST gene family on the risk of developing type-2 diabetes mellitus and on glycemic control. We also investigated the effects of smoking combined with these polymorphisms on type-2 diabetes mellitus r.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.31.14
- DOI:
- 10.4238/2011.October.31.14
Effect of pulsed electromagnetic field therapy on the osteogenic and adipogenic differentiation of bone marrow mesenchymal stem cells
Authors: T. Lu, Y.X. Huang, C. Zhang, M.X. Chai and J. Zhang
We investigated the effects of pulsed electromagnetic fields (PEMFs) of 20 Hz/2 mT on the osteogenic and adipogenic differentiation of bone marrow stem cells (BMSCs). Sprague Dawley rat BMSCs were isolated and cultured in vitro. The BMSCs of the third passage were obtained and stimulated by PEMFs of 20 Hz/2 mT. The alkaline phosphatase (ALP) activity was .. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.28.5
- DOI:
- http://dx.doi.org/10.4238/2015.September.28.5
Correlation between single nucleotide polymorphisms in hypoxia-related genes and susceptibility to acute high-altitude pulmonary edema
Authors: A.L. Wu, Y.S. Xiong, Z.Q. Li, Y.G. Liu, Q. Quan and L.J. Wu
This study aimed to explore the relationship between genetic changes and high-altitude pulmonary edema (HAPE) susceptibility, and to screen for the key single nucleotide polymorphism (SNP) loci in the HAPE-susceptibility gene, by investigating the SNPs occurring in hypoxia-related genes in HAPE-susceptible and control (non-susceptible) populations. This r.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.28.8
- DOI:
- http://dx.doi.org/10.4238/2015.September.28.8
Functional molecular markers (EST-SSR) in the full-sib reciprocal recurrent selection program of maize (Zea mays L.)
Authors: K.S.C. Galv�£o, H.C.C. Ramos, P.H.A.D. Santos, G.C. Entringer, J.C.F. Vettorazzi and M.G. Pereira
This study aimed to improve grain yield in the full-sib reciprocal recurrent selection program of maize from the North Fluminense State University. In the current phase of the program, the goal is to maintain, or even increase, the genetic variability within and among populations, in order to increase heterosis of the 13th cycle of reciprocal recurrent se.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.3.10
- DOI:
- 10.4238/2015.July.3.10
Elimination of breast tumor-associated chondroitin sulfate promotes metastasis
Authors: R.D. Prinz, C.M. Willis, A. Viloria-Petit and M. Kl�¼ppel
Breast cancer is one of the leading causes of cancer-related deaths amongst women in the USA. The tumor microenvironment has been suggested to be an attractive therapeutic target for treatment of cancers. The glycosaminoglycan chondroitin sulfate, as part of the cellular microenvironment, consists of long linear chains of repe.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.8.9
- DOI:
- 10.4238/2011.December.8.9