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Genetic divergence of common bean cultivars
Authors: J.S. Veloso, W. Silva, L.R. Pinheiro, J.B. dos Santos, N.S. Fonseca Jr. and M.P. Euzebio
The aim of this study was to evaluate genetic divergence in the ‘Carioca’ (beige with brown stripes) common bean cultivar used by different institutions and in 16 other common bean cultivars used in the Rede Cooperativa de Pesquisa de Feijão (Cooperative Network of Common Bean Research), by using simple sequence repeats associated with .. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.22.22
- DOI:
- http://dx.doi.org/10.4238/2015.September.22.22
Development of novel microsatellite markers in the Korean rockfish Sebastes schlegeli
Authors: H.-T. Ma, C.-F. Jia, J.-M. Yang, F. Wang, R. Xue, C.-H. Han and H.-B. Jiang
The Korean rockfish Sebastes schlegeli is a valuable recreational and commercial fish in China, and is cultured in land-based tanks and net cages. Fifteen microsatellite markers were developed for this species, and their polymorphisms were examined in a population. The allele number of the 15 markers ranged from 2 to 13, with an average of 5.933 per locus.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.12.12
- DOI:
- 10.4238/2015.May.12.12
The ratio of transforming growth factor-�²1/bone morphogenetic protein-7 in the progression of the epithelial-mesenchymal transition contributes to rat liver fibrosis
Authors: W.R. Bi, G.T. Xu, L.X. Lv and C.Q. Yang
This study was designed to show whether rat liver epithelial cells could undergo epithelial-mesenchymal transition (EMT), thereby directly contributing to liver fibrosis. The role of the ratio of transforming growth factor-β1 (TGF-β1)/bone morphogenetic protein-7 (BMP-7) was evaluated in the progression of EMT or mes.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.February.20.2
- DOI:
- 10.4238/2014.February.20.2
A repetitive sequence assembler based on next-generation sequencing
Authors: S. Lian, Y. Tu, Y. Wang, X. Chen and L. Wang
Repetitive sequences of variable length are common in almost all eukaryotic genomes, and most of them are presumed to have important biomedical functions and can cause genomic instability. Next-generation sequencing (NGS) technologies provide the possibility of identifying capturing these repetitive sequences directly from the NGS data. In this study, we .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038790
- DOI:
- 10.4238/gmr.15038790
Association of CHRNA4 gene rs1044396 and rs1044397 polymorphisms with Parkinson�s disease symptoms and smoking
Authors: L.M. Zhang, X.P. Zhang, Y.Q. Chen and W. Ye
We assessed the CHRNA4 exon 5 rs1044396 and rs1044397 polymorphisms and investigated their relationship with Parkinson’s disease (PD) severity and several non-motor symptoms. Ninety-seven patients with primary PD and 108 controls were recruited, and their smoking history identified. Patients with PD were assessed using the unified PD rating scale (U.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.12.14
- DOI:
- 10.4238/2015.May.12.14
hBMP-7 induces the differentiation of adipose-derived mesenchymal stem cells into osteoblast-like cells
Authors: Y. Ren, C. Han, J. Wang, Y. Jia, L. Kong, T. Eerdun, L. Wu and D. Jiang
The aim of this study was to investigate the differentiation potential of adipose-derived mesenchymal stem cells (ADMSCs) into osteoblasts by human bone morphogenetic protein-7 (hBMP-7) induction. ADMSCs were isolated from the subcutaneous adipose tissue of a rabbit, and then transfected with the pcDNA3.1 vector alone and pcDNA3.1-hBMP-7 (hBMP-7), respect.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038791
- DOI:
- 10.4238/gmr.15038791
Protein-protein interaction network construction for cancer using a new L1/2-penalized Net-SVM model
Authors: H. Chai, H.H. Huang, H.K. Jiang, Y. Liang and L.Y. Xia
Identifying biomarker genes and characterizing interaction pathways with high-dimensional and low-sample size microarray data is a major challenge in computational biology. In this field, the construction of protein-protein interaction (PPI) networks using disease-related selected genes has garnered much attention. Support vector machines (SVMs) are commo.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038794
- DOI:
- 10.4238/gmr.15038794
Long-term effects of evodiamine on expressions of lipogenesis and lipolysis genes in mouse adipose and liver tissues
Authors: D.F. Jiang, W.T. Li2, H.L. Yang, Z.Z. Zhang, D. Chen and C. Sun
Evodiamine, the major alkaloid component isolated from the fruit of dried, unripened Evodia rutaecarpa Bentham, affects the plasma levels of cholecystokinin and various biological events such as gastric emptying and gastrointestinal transit; these effects of evodiamine were previously investigated in male rats. In this study, .. Read More»
- Genet. Mol. Res. 13(1):
- 2014.February.20.5
- DOI:
- 10.4238/2014.February.20.5
Paracoccidioides brasiliensis RNA biogenesis apparatus revealed by functional genome analysis
Authors: PatrÃ?Âcia Albuquerque, Alessandra J. Baptista, Lorena da Silveira Derengowsky, Luciano ProcÃ?³pio, AndrÃ?© Moraes Nicola, FabrÃ?Âcio B.M. Arraes, Diorge Paulo de Souza, Cynthia Maria Kyaw and Ildinete Silva-Pereira
The RNA biogenesis machinery of Paracoccidioides brasiliensis was assessed by comparative analyses of PbAESTs (P. brasiliensis assembled expressed sequence tags (ESTs)) with sequences from Saccharomyces cerevisiae MIPS database. PbAESTs related to almost all categories of S. cerevisiae RNA biogenesis were found. Two of the 12 .. Read More»
- Genet. Mol. Res. 4(2):
General metabolism of the dimorphic and pathogenic fungus Paracoccidioides brasiliensis
Authors: FabrÃ?Âcio B.M. Arraes, Bruno Benoliel, Rafael T. Burtet, PatrÃ?Âcia L.N. Costa, Alexandro S. Galdino, Luanne H.A. Lima, Camila Marinho-Silva, Luciana Oliveira-Pereira, Pollyanna Pfrimer, Luciano ProcÃ?³pio-Silva, Viviane Castelo-Branco Reis and Maria Sueli S. Felipe
Annotation of the transcriptome of the dimorphic fungus Paracoccidioides brasiliensis has set the grounds for a global understanding of its metabolism in both mycelium and yeast forms. This fungus is able to use the main carbohydrate sources, including starch, and it can store reduced carbons in the form of glycogen and trehal.. Read More»
- Genet. Mol. Res. 4(2):