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A comparative study on genetic characteristics of two new varieties of Pelodiscus sinensis and their hybrid
Authors: H.Q. Zhang, X.J. Xu, Z.Y. He, J.Z. Shao, X.H. Zhang, Q.H. Meng and F.Y. Huang
Chinese soft-shelled turtle Pelodiscus sinensis has been an important aquaculture species in Southeast Asian countries. To breed a new variety of soft-shelled turtle with excellent properties and to evaluate the effect of hybridization of two turtle strains with a highly different trait phenotype, inheritance, microsatellite l.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039148
- DOI:
- 10.4238/gmr16039148
Clinical features of Mexican patients with Mucopolysaccharidosis type I
Authors: A. Alonzo-Rojo, J.E. GarcÃ?Âa-Ortiz, M. Ortiz-Aranda, M.P. Gallegos-Arreola and L.E. Figuera-Villanueva
Mucopolysaccharidosis type I (MPS-I) is an autosomal recessive lysosomal storage disorder caused by a deficiency or absence of α-l-iduronidase, which is involved in the catabolism of glycosaminoglycans (GAGs). This deficiency leads to the accumulation of GAGs in several organs. Given the wide spectrum of the disease, MPS.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16032602
- DOI:
- 10.4238/gmr16032602
Characterization of glucose-tolerant �²-glucosidases used in biofuel production under the bioinformatics perspective: a systematic review
Authors: D.C.B. Mariano, C. Leite, L.H.S. Santos, L.F. Marins, K.S. Machado, A.V. Werhli, L.H.F. Lima and R.C. de Melo-Minardi
β-glucosidases are enzymes that catalyze the hydrolysis of oligosaccharides and disaccharides, such as cellobiose. These enzymes play a key role in cellulose degrading, such as alleviating product inhibition of cellulases. Consequently, they have been considered essential for the biofuel industry. However, the majority of.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039740
- DOI:
- 10.4238/gmr16039740
Diallel and prediction (REML/BLUP) for yield components in intervarietal maize hybrids
Authors: I.R. Carvalho, A.J. de Pelegrin, V.J. Szareski, M. Ferrari, T.C. da Rosa, T.S. Martins, N.L. dos Santos, M. Nardino, V.Q. de Souza, A.C. de Oliveira and L.C. da Maia
Genetic improvement is essential to achieve increments in maize (Zea mays L.) grain yield components. It may be obtained through crosses, which enable to exploit the effects of intervarietal heterosis, allelic complementarity, as well as gene actions and effects. This study estimated the components of variance and genetic para.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039734
- DOI:
- 10.4238/gmr16039734
Mutational screening in the LDLR gene among patients presenting familial hypercholesterolemia in the Southeast of Brazil
Authors: G.A. Molfetta, D.L. Zanette, J.E. Santos and W.A. Silva Jr
Familial hypercholesterolemia (FH) is a dominant, autosomal disease characterized by high LDL levels in blood plasma, and is caused by a defect in the gene encoding the LDL receptor (LDLR). The clinical diagnosis is based on personal and familial history, physical examination findings, and measures of high LDL cholesterol conc.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039226
- DOI:
- 10.4238/gmr16039226
MiR-200c inhibits metastasis of breast tumor via the downregulation of Foxf2
Authors: T. Zhang, J.G. Wan, J.B. Liu and M. Deng
The forkhead box F2 (Foxf2) gene suppresses epithelial-mesenchymal transition via the modulation of transcription of zinc finger E-box-binding homeobox 1 (Zeb1) and epithelial (E)-cadherin, thereby inhibiting tumor metastasis. Additionally, the specific binding of microRNA (miR)-200c to Foxf2 mRNA impedes metastatic pulmonary .. Read More»
- Genet. Mol. Res. 16(3):
- gmr16038971
- DOI:
- 10.4238/gmr16038971
Assessment of genetic diversity of a native population of Eplingiella fruticosa: a plant with therapeutic potential
Authors: D.C. Silva, L.E.C. Diniz, A.F. Blank, D.A.C. Nizio, J.A.O. Pinto, K.L.G. Pereira and M.F. Arrigoni-Blank
Eplingiella fruticosa (Salzm. ex Benth.) Harley & J.F.B. Pastore, ex Hyptis fruticosa Salzm. ex Benth. is an aromatic and medicinal plant of the family Lamiaceae, found mainly in regions with intense anthropic activity. Information on the genetic diversity of this species is scarce. However, it can be assessed using molecu.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039749
- DOI:
- 10.4238/gmr16039749
Synergic effect of oral contraceptives, GSTP1 polymorphisms, and high-risk HPV infection in development of cervical lesions
Authors: B.S. Chagas, A.P.A.D. Gurgel, S.S.L. Paiva J�ºnior, R.C.P. Lima,M.N. Cordeiro, R.R. Moura, A.V.C. Coelho, K.C.G. Nascimento,J.C. Silva Neto, S. Crovella and A.C. Freitas
Human papillomavirus (HPV) infection is considered a risk factor for cervical cancer. Even if the high-risk HPV (HR-HPV) infection is necessary, environmental co-factors and genetic susceptibility also play an important role in cervical cancer development. In this study, a possible association of rs1695 GSTP1 polymorphisms, HR.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039742
- DOI:
- 10.4238/gmr16039742
Stability of annual biomass energy production of elephant grass (Pennisetum purpureum Schum.) genotypes in the Northern region of the Rio de Janeiro State, Brazil
Authors: M.S.B. Ara�ºjo, R.F. Daher, B.R.S. Menezes, G.A. Gravina, V.B. Silva, A.T. Amaral J�ºnior, E.V. Rodrigues, B.O. Almeida and N.J. Ponciano
The objectives of this study were to estimate the stability of dry biomass production of elephant grass genotypes under an annual harvest regime, in soil-climatic conditions of the Northern region of the Rio de Janeiro State, Brazil, and to compare methodologies for stability analyses of Yates and Cochran (YC), Plaisted and Pe.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039041
- DOI:
- 10.4238/gmr16039041
Genotypic gain with simultaneous selection of production, nutrition, and culinary traits in cowpea crosses and backcrosses using mixed models
Authors: D.G. Oliveira, M.M. Rocha, K.J. Damasceno-Silva, F.V. S�¡, L.R.L. Lima, and M.D.V. Resende
The aim of this study was to estimate the genotypic gain with simultaneous selection of production, nutrition, and culinary traits in cowpea crosses and backcrosses and to compare different selection indexes. Eleven cowpea populations were evaluated in a randomized complete block design with four replications. Fourteen traits .. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039736
- DOI:
- 10.4238/gmr16039736