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Gene

Plant Genetics   Research Article

Genetic diversity and population genetic structure of the miiuy croaker, Miichthys miiuy, in the East China Sea by microsatellite markers

Authors: Y. Qin, D.Q. Sun, T.J. Xu, X.Z. Liu and Y.N. Sun

Genetic diversity and patterns of population structure of the miiuy croaker were investigated using SSR markers. A set of 10 microsatellite loci revealed 40 alleles; the number of alleles varied from 2 to 10 for each marker. A relatively high level of genetic variability was observed between miiuy croaker individuals. Genetic diversity was relatively high.. Read More»

Genet. Mol. Res. 13(4):
2014.December.18.1
DOI:
10.4238/2014.December.18.1
Plant Genetics   Research Article

Karyomorphology and karyotype asymmetry in the South American Caesalpinia species (Leguminosae and Caesalpinioideae)

Authors: P.S. Rodrigues, M.M. Souza and R.X. CorrĂ?ÂȘa

With the purpose of addressing the pattern of karyotype evolution in Caesalpinia species, chromosome morphology was characterized in five species from Brazil, and karyotypic asymmetry was analyzed in 14 species from South America. All accessions had the chromosome number 2n = 24, which was first described here for Caesalpinia laxiflora Tul. and Cenostigma.. Read More»

Genet. Mol. Res. 13(4):
2014.October.20.4
DOI:
10.4238/2014.October.20.4
Human Genetics   Research Article

Mining topological structures of protein-protein interaction networks for human brain-specific genes

Authors: W.J. Cui, X.J. Gong, H. Yu and X.C. Zhang

Compared to other placental mammals, humans have unique thinking and cognitive abilities because of their developed cerebral cortex composed of billions of neurons and synaptic connections. As the primary effectors of the mechanisms of life, proteins and their interactions form the basis of cellular and molecular functions in .. Read More»

Genet. Mol. Res. 14(4):
2015.October.16.10
DOI:
10.4238/2015.October.16.10
Human Genetics   Research Article

Association between polymorphisms of fat mass and obesity-associated gene and metabolic syndrome in Kazakh adults of Xinjiang, China

Authors: Y.H. Hu, J.M. Liu, M. Zhang, R.L. Ma, H. Guo, K. Wang, J. He, Y.Z. Yan, D.S. Rui, F. Sun, L.T. Mu, Q. Niu, Y.S. Ding, J.Y. Zhang, S.G. Li and S.X. Guo

The aim of this study was to assess the association between three FTO polymorphisms (rs9939609, rs8057044, and rs1421085) and metabolic syndrome (MS)-related outcomes in the low-income, rural, nomadic minority Khazakh population in far western China. A total of 489 subjects (245 MS patients, 244 controls) were included in the study and DNA samples were ge.. Read More»

Genet. Mol. Res. 14(4):
2015.November.18.23
DOI:
10.4238/2015.November.18.23
Human Genetics   Research Article

Expression and significance of the imprinted gene PEG10 in placenta of patients with preeclampsia

Authors: X.Y. Liang, X. Chen, Y.Z. Jin, X.O. Chen and Q.Z. Chen

The aim of this study was to investigate the expression and significance of the imprinted gene PEG10 (paternally expressed gene 10) in preeclampsia placental tissue. Quantitative real-time reverse transcriptase polymerase chain reaction and immunohistochemistry to evaluate mRNA and protein expression and distribution of PEG10 in placental tissues obtained.. Read More»

Genet. Mol. Res. 13(4):
2014.December.18.2
DOI:
10.4238/2014.December.18.2
Animal Genetics   Research Article

Intestinal lactic acid bacteria from Muscovy duck as potential probiotics that alter adhesion factor gene expression

Authors: Z.L. Xie, D.P. Bai, L.N. Xie, W.N. Zhang, X.H. Huang and Y.F. Huang

The purpose of this study was to assess the suitability of lactic acid bacteria (LABs) isolated from Muscovy duck as a potential probiotic. Isolates were identified by targeted polymerase chain reaction and assessed in vitro for probiotic characteristics such as autoaggregation; surface-charge; hydrophobicity; tolerance to aci.. Read More»

Genet. Mol. Res. 14(4):
2015.October.9.15
DOI:
10.4238/2015.October.9.15
Animal Genetics   Research Article

Haplo-block structure of Southern African village chicken populations inferred using genome-wide SNP data

Authors: K.S. Khanyile, E.F. Dzomba and F.C. Muchadeyi

This study investigated the haplo-block structure, haplotype sharing, and diversity in extensively raised chicken populations of Southern Africa. Two hundred ninety village chickens from Malawi (N = 30), South Africa (N = 132), and Zimbabwe (N = 128) were included in the study, from which 649, 2104, and 2442 haplo-blocks were .. Read More»

Genet. Mol. Res. 14(4):
2015.October.9.16
DOI:
10.4238/2015.October.9.16
Human Genetics   Research Article

Lack of association between the hOGG1 gene Ser326Cys polymorphism and gastric cancer risk: evidence from a case-control study anda meta-analysis

Authors: W.G. Hu, R.J. Pan, W. Cai, Z.T. Wang and Z.G. Zhu

The association between the human 8-oxoguanine glycosylase 1 (hOGG1) gene Ser326Cys polymorphism (rs1052133) and gastric cancer has been widely evaluated, yet a definitive answer to whether this association exists is lacking. We first conducted a case-control study to assess this association in a large Han Chinese population, and then performed a meta-ana.. Read More»

Genet. Mol. Res. 14(4):
2015.November.18.31
DOI:
10.4238/2015.November.18.31
Human Genetics   Research Article

Is there a relationship between polyploidy and stressful environments? A case study of inselbergs in northeastern Brazil

Authors: S.R. Pitrez, L.A. Andrade, F.N.M. Assis and L.P. Felix

The aim of this study was to examine the hypothesis that plants with higher ploidy levels are selected by environments under more extremely stressful conditions than the same (or closely related) species from less rigorous terrestrial or epiphytic habitats. Therefore, we analyzed the chromosome numbers of 26 species belonging to 21 genera and 13 families .. Read More»

Genet. Mol. Res. 13(4):
2014.October.20.11
DOI:
10.4238/2014.October.20.11
Human Genetics   Research Article

Interaction of six candidate genes in essential hypertension

Authors: D.C. Hu, X.L. Zhao, J.C. Shao, W. Wang, J. Qian, A.H. Chen, H.Q. Zhang, H. Guo, J. Jiang and H.Y. Li

We explored the interaction of 6 candidate genetic mutations in essential hypertension (EH). The mutations AGT M235T, ACE I/D, eNOS Glu298Asp, ET-2 A985G, ANP T2238C, and NPRC A-55C were detected using a genechip microarray in 100 patients with EH and 97 controls from the Han population living in the Yunnan Province of China. Risks of EH were evaluated wi.. Read More»

Genet. Mol. Res. 13(4):
2014.October.20.14
DOI:
10.4238/2014.October.20.14