Genetic variability in accessions of the acerola germplasm bank of Universidade Federal Rural de Pernambuco, Brazil
Authors: R.M. Moraes Filho1, L.S.S. Martins2, R.S. Musser3, A.V.V. Montarroyos3 and E.F. Silva2
Brazil is the world’s largest producer of acerola, Malpighia emarginata (Malpighiaceae); the Northeast is responsible for 60% of the national production. The culture of acerola in Brazil has great genetic variability; plantings have high phenotypic diversity and are not very productive, often originating from propagation by seed. We evaluated the ge.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.29.8
- DOI:
- 10.4238/2013.October.29.8
In vitro effects of Ala16Val manganese superoxide dismutase gene polymorphism on human white blood cells exposed to methylmercury
Authors: T.D. Algarve1, F. Barbisan2, E.E. Ribeiro3, M.M.M.F. Duarte4, M.F. M�¢nica-Cattani1, C.P. Mostardeiro2, A.F. Lenz1 and I.B.M. da Cruz1,2,4
Environmental contamination by methylmercury (MeHg) is an enormous public health problem in world regions such as Amazonia. MeHg toxic effects seem to be influenced by environmental and genetic factors. However, few studies have evaluated the genetic influences of MeHg toxicity in humans. Therefore, the aim of this study was to evaluate the genetic influe.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.29.7
- DOI:
- 10.4238/2013.October.29.7
Genetic composition of a Brazilian population: the footprint of the Gold Cycle
Authors: E.M. Queiroz1, A.M. Santos2, I.M. Castro2, G.L.L. Machado-Coelho3, A.P.C. C�¢ndido4, T.M. Leite5, R.W. Pereira5 and R.N. Freitas1
Ancestry-informative markers (AIMs) are powerful tools for inferring the genetic composition of admixed populations. In this study, we determined the genetic ancestry of the Ouro Preto (Brazil) population and evaluated the association between ancestry and self-reported skin color. The genetic ancestry of 189 children and adolescents was estimated by genot.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.29.6
- DOI:
- 10.4238/2013.October.29.6
Evaluation of genetic diversity in Pampus argenteus using SSR markers
Authors: Y. Qin, G. Shi and Y. Sun
In order to evaluate the germplasm resources of Pampus argenteus silver pomfret, the genetic diversity and population structure of 132 silver pomfret samples collected from the three regions (the East China Sea, the Yellow Sea and the Bohai Sea) were examined using 13 polymorphic microsatellite loci. Results indicated a high level of genetic diversity. Th.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.22.10
- DOI:
- 10.4238/2013.November.22.10
Cloning and characterization of major histocompatibility complex class II genes in the stone flounder Kareius bicoloratus (Pleuronectidae)
Authors: Cloning and characterization of major histocompatibility complex class II genes in the stone flounder Kareius bicoloratus (Pleuronectidae)
Major histocompatibility complex (MHC) class II genes play important recognition roles in the immune system in vertebrates. We cloned the MHC class II genes A and B in the stone flounder (Kareius bicoloratus). The full-length cDNA and DNA sequences of both genes were obtained, and their characteristic motifs were analyzed. The DNA sequence of stone flound.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.22.9
- DOI:
- 10.4238/2013.November.22.9
Entoepidemiology of Chagas disease in northwest S�£o Paulo and cytogenetic analysis of its main vector, Triatoma sordida (Hemiptera: Triatominae)
Authors: R. Silistino-Souza1, K.C.C. Alevi1, N.F.C. Castro1, M.N. Freitas1, M.D. Papa2, S.A.S. Scandar2, R.R. Bestetti3, J.A. Rosa4 and M.T.V. Azeredo-Oliveira
One century after the discovery of Chagas disease, it is still considered as a major health problem, causing more deaths in the Americas than any other parasitic disease. The northwest region of São Paulo, a macro-region that includes cities with a high-quality of life, has particularly high rates of Chagas disease... Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.22.8
- DOI:
- 10.4238/2013.November.22.8
Polymorphism of SREBP1 is associated with beef fatty acid composition in Simmental bulls
Authors: L. Xu*, L.P. Zhang*, Z.R. Yuan, L.P. Guo, M. Zhu, X. Gao, H.J. Gao, J.Y. Li and S.Z. Xu
The sterol regulatory element binding factor 1 gene (SREBP1) plays an important role in the biosynthesis of fatty acids and cholesterol, and in lipid metabolism. The objective of this study was to investigate the effect of genetic polymorphisms of SREBP1 on the fatty acid composition of muscle and carcass traits in Simmental bulls and Snow Dragon black ca.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.22.7
- DOI:
- 10.4238/2013.November.22.7
Further evidence for the contribution of the BRCA1-interacting protein-terminal helicase 1 (BRIP1) gene in breast cancer susceptibility
Authors: L.P. Ren, Y.S. Xian, D.M. Diao, Y. Chen, Q. Guo and C.X. Dang
BRCA1-interacting protein C-terminal helicase 1 (BRIP1) is a DNA helicase that influences the DNA repair ability and tumor suppressor function of BRCA1. Truncating BRIP1 mutations have been described as cancer susceptibility alleles. To evaluate BRIP1 polymorphisms as risk factors for breast cancer, we performed a detailed analysis of possible single nucl.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.22.6
- DOI:
- 10.4238/2013.November.22.6
Expression pattern of the zona pellucida 3 (ZP3) gene during ovarian development and the location of ZP3 protein in oocytes in a natural, wild triploid crucian carp mutant, Carassius auratus var. Pingxiangnensis
Authors: J.W. Shi1, J.Q. Sheng1, K. Peng1, J.H. Wang1, W.J. Yi1, H.J. Wu2, Q. Gu1 and Y.J. Hong1,3
Carassius auratus var. Pingxiangnensis (designated CaP), distributed in the Pingxiang region of Jiangxi Province, China, is a natural, wild triploid crucian carp mutant that has two reproductive development modes: gynogenesis and bisexual reproduction. Little information is available about the expression pattern of the zona pellucida 3 (ZP3) gene during o.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.18.13
- DOI:
- 10.4238/2013.November.18.13
Deposition rule of yolk cholesterol in two different breeds of laying hens
Authors: P.K. Yang*, Y.D. Tian*, G.R. Sun, R.R. Jiang, R.L. Han and X.T. Kang
The objective of this study was to investigate the deposition rule of yolk cholesterol in Lushi Green-shelled and Silky Fowl layers. A total of 90 layers of each breed were selected at an age of 15 to 51 weeks. Productive performance was recorded on a weekly basis, whereas yolk cholesterol was determined at 4-week intervals from 21 to 51 weeks of age. The.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.22.5
- DOI:
- 10.4238/2013.November.22.5