Application of RNA-seq to reveal the transcript profile in bacteria
Authors: A.C. Pinto, H.P. Melo-Barbosa, A. Miyoshi, A. Silva and V. Azevedo
The large number of microbial genomes deposited in databanks has opened the door for in-depth studies of organisms, including post-genomics investigations. Thanks to new generation sequencing technology, these studies have made advances that have lead to extraordinary discoveries in bacterial transcriptomics. In this review, w.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1554
- DOI:
- 10.4238/vol10-3gmr1554
Interleukin-10 promoter polymorphisms associated with susceptibility to lumbar disc degeneration in a Chinese cohort
Authors: W.P. Lin, J.H. Lin, X.W. Chen, C.Y. Wu, L.Q. Zhang, Z.D. Huang and J.M. Lai
We investigated a possible association between interleukin (IL)-10 single nucleotide polymorphisms (SNPs) and susceptibility to and severity of lumbar disc degeneration (LDD) in a Chinese cohort of 320 patients with LDD and 269 gender- and age-matched controls. The degree of disc degeneration was determined by magnetic resonan.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1283
- DOI:
- 10.4238/vol10-3gmr1283
Meiotic behavior and pollen viability in Moringa oleifera (Moringaceae) cultivated in southern Brazil
Authors: N. Silva, A.B. Mendes-Bonato, J.G.C. Sales and M.S. Pagliarini
Although originally from India, Moringa oleifera is now cultivated throughout most of the tropics, including Brazil. Despite its multipurpose value for food and traditional medicine, little is known about the meiotic behavior and pollen viability of M. oleifera. We evaluated microsporogenesis and pollen viability in eleven pla.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1490
- DOI:
- 10.4238/vol10-3gmr1490
Psychogenetics of Ullrich-Turner syndrome (an investigation of 28 subjects and respective controls through the Bender test and Piagetian scales) (PsicogenÃ?©tica da sÃ?Ândrome de Ullrich-Turner (investigaÃ?§Ã?£o de 28 sujeitos com respectivos controles atravÃ?©s do teste de Bender e das escalas de Piaget))
Authors: F�¡tima do Carmo Fonseca Ricardi
Piagetian scales (PS) and Bender visual motor gestalt test (BT), as well as laterality and Ishihara tests, were applied to 28 subjects with universal 45,X Ullrich-Turner syndrome (UTS), and their respective controls, in order to investigate their cognitive performance. Dermatoglyphics were also analyzed to obtain “clues&.. Read More»
- Genet. Mol. Res. 4(4):
Allele frequencies and genetic diversity in two groups of wild tufted capuchin monkeys (Cebus apella nigritus) living in an urban forest fragment
Authors: Jeanne Margareth Jimenes Amaral, Aguinaldo Luiz Sim�µes and David De Jong
There have been numerous studies genetically characterizing Old World Primates using microsatellites. However, few studies have been made of New World species and none on free-ranging Cebus apella, even though it is probably the most widely distributed species of monkey in the New World. The paucity of studies is due, in part,.. Read More»
- Genet. Mol. Res. 4(4):
Genotoxic effects of rotenone on cultured lymphocytes
Authors: PatrÃ?Âcia Danielle Lima de Lima, Elizabeth Sumi Yamada, Edmar Tavares da Costa, Claudia do O. Pessoa, Silvia Helena Barem Rabenhorst, Marcelo de Oliveira Bahia, PlÃ?Ânio Cerqueira Cardoso, Raquel Alves Santos, Marilia de Arruda Cardoso Smith and Rommel RodrÃ?Âguez Burbano
Rotenone is a heterocyclic compound widely used as an insecticide, acaricide and piscicide. Its toxicity is mainly caused by the inhibition of mitochondrial respiratory processes and ATP production, resulting in the generation of reactive oxygen species. Reactive oxygen species can interact with DNA, RNA and proteins, leading .. Read More»
- Genet. Mol. Res. 4(4):
In silico characterization of 1,2-diacylglycerol cholinephosphotransferase and lysophosphatidylcholine acyltransferase genes in Glycine max L. Merrill
Authors: C.S. Sousa, B.A. Barros, D. Barh, P. Ghosh, V. Azevedo, E.G. Barros and M.A. Moreira
The enzymes 1,2-diacylglycerol cholinephosphotransferase (CPT) and lysophosphatidylcholine acyltransferase (LPCAT) are important in lipid metabolism in soybean seeds. Thus, understanding the genes that encode these enzymes may enable their modification and aid the improvement of soybean oil quality. In soybean, the gene.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038974
- DOI:
- 10.4238/gmr.15038974
Isolation of transfected fibroblast clones for use in nuclear transfer and transgene detection in cattle embryos
Authors: Eduardo O. Melo, Regivaldo V. Sousa, LÃ?Âlian T. Iguma, MaurÃ?Âcio M. Franco, Elibio L. Rech and Rodolfo Rumpf
Transgenesis in cattle has provided numerous opportunities for livestock production. The development of nuclear transfer (NT) technology has improved the production of transgenic livestock. However, the isolation of pure colonies from a single transfection event remains laborious and can be a constraint in the production of tr.. Read More»
- Genet. Mol. Res. 4(4):
Differential molecular response of the transcripts B2A2 and B3A2 to imatinib mesylate in chronic myeloid leukemia
Authors: Jos�© Alexandre Rodrigues de Lemos, Ciane Martins de Oliveira, Ana Carolina Costa Scerni, Alessandra Q. Bentes, Ana Cristina Beltr�£o, I�ª Regina G. Bentes, Tereza Cristina Azevedo and Luciana Maria Cunha Maradei-Pereira
Chronic myeloid leukemia (CML) originates from the hematopoietic stem cell and is characterized by the reciprocal translocation t(9;22)(q34;q11), which results in the BCR-ABL fusion gene on chromosome 22q-, also known as the Philadelphia chromosome. This chimeric gene codes for a cytoplasmic protein with constitutive tyrosinek.. Read More»
- Genet. Mol. Res. 4(4):
Detecting multiple DNA human profile from a mosquito blood meal
Authors: K.C.N. Rab�ªlo, C.M.R. Albuquerque, V.B. Tavares, S.M. Santos, C.A. Souza, T.C. Oliveira, R.R. Moura, L.A.C. Brand�£o and S. Crovella
Criminal traces commonly found at crime scenes may present mixtures from two or more individuals. The scene of the crime is important for the collection of various types of traces in order to find the perpetrator of the crime. Thus, we propose that hematophagous mosquitoes found at crime scenes can be used to perform genetic testing of human blood and aid.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15037547
- DOI:
- 10.4238/gmr.15037547