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Human Genetics   Research Article

Influence of aberrant myeloid expression on acute lymphoblastic leukemia in children and adolescents from Maranh�£o, Brazil

Authors: T.C. Lopes1, K.N.S. Andrade1, N.L. Camelo1, V.P. Rodrigues2 and R.A.G. Oliveira3

The aim of this study was to evaluate myeloid expression in acute lymphoblastic leukemia (ALL) in children and adolescents who had been referred to the Oncology Department in a hospital in the State of Maranhão based on demographic, laboratory, and clinical data. Myeloid expression was evaluated in 65 patients under 18 years of age who were diagnos.. Read More»

Genet. Mol. Res. 13(4):
2014.December.4.25
DOI:
10.4238/2014.December.4.25
Plant Genetics   Research Article

Association between DLK1 and IGF-I gene expression and meat quality in sheep

Authors: R. Su1, W. Sun1, D. Li1, Q.Z. Wang1, X.Y. Lv1, H.H. Musa2, L. Chen3, Y.F. Zhang3 and W.Z. Wu3

The aim of the present study was to detect delta-like 1 homolog (DLK1) and insulin-like growth factor-I (IGF-I) gene expression in the longissimus dorsi of Hu sheep at different growth stages and study the association between these genes and meat quality... Read More»

Genet. Mol. Res. 13(4):
2014.December.4.26
DOI:
10.4238/2014.December.4.26
Medical Genetics   Research Article

Comparison of small scale methods for the rapid and efficient extraction of mitochondrial DNA from wheat crop suitable for down stream processes

Authors: M. Ejaz*, Z. Qidi*, Z. Gaisheng, W. Qunzhu, N. Na and Z. Huiyan

We evaluated and compared 2 mitochondrial DNA (mtDNA) extraction methods in terms of DNA quality and success of subsequent polymerase chain reaction (PCR) amplifications from etiolated leaves of wheat crop (Triticum aestivum). mtDNA extraction is difficult because the presence of metabolites interfere with DNA isolation procedures and downstream applicati.. Read More»

Genet. Mol. Res. 13(4):
2014.December.4.27
DOI:
10.4238/2014.December.4.27
Bioinformatics   Research Article

Increasing genetic variability in black oats using gamma irradiation

Authors: G. Silveira1, E. Moliterno2, G. Ribeiro3, P.M.A. Costa1, L.G. Woyann4, E.W. Tessmann4, A.C. Oliveira4 and C.D. Cruz1

The black oat (Avena strigosa Schreb) is commonly used for forage, soil cover, and green manure. Despite its importance, little improvement has been made to this species, leading to high levels of genotypic disuniformity within commercial cultivars. The objective of this study was to evaluate the efficiency of different doses of gamma rays [60Co] applied .. Read More»

Genet. Mol. Res. 13(4):
2014.December.4.28
DOI:
10.4238/2014.December.4.28
Human Genetics   Research Article

DNA barcoding for species identification in the Palmae family

Authors: A. Naeem1, A.A. Khan1, H.M.N. Cheema1, I.A. Khan1 and A. Buerkert2

DNA barcoding is a promising tool for species identification at the molecular level. The barcoding system is well established for species differentiation in animals, while it is less common in plants. We evaluated 2 barcoding regions, maturase K (matK) and ribulose bisphosphate carboxylase (rbcL), to compare species of Palmae according to amplification su.. Read More»

Genet. Mol. Res. 13(4):
2014.December.4.29
DOI:
10.4238/2014.December.4.29
Plant Genetics   Research Article

Genetic control of inflorescence in common bean

Authors: S.R. Guilherme1, M.A.P. Ramalho1, A. de F.B. Abreu2 and L.A. Pereira1

The number of pods per common bean plant is a primary component of grain yield, which depends on the number of flowers produced and on the flower set. Thus, a larger number of flowers per plant would increase yield. Lines with inflorescences that had a large number of flowers compared to common bean plants now under cultivation were identified. We analyze.. Read More»

Genet. Mol. Res. 13(4):
2014.December.4.30
DOI:
10.4238/2014.December.4.30
Plant Genetics   Research Article

Polymorphic microsatellite markers for the rare and endangered cactus Uebelmannia pectinifera (Cactaceae) and its congeneric species

Authors: E.M. Moraes1, F.W. Cidade1, G.A.R. Silva1 and M.C. Machado2

The cactus genus Uebelmannia includes 3 narrow endemic species associated with rocky savanna habitats in eastern South America. Because of their rarity and illegal over-collection, all of these species are endangered. Taxonomic uncertainties resulting from dramatic local variation in morphology within Uebelmannia species preclude effective conservation ef.. Read More»

Genet. Mol. Res. 13(4):
2014.December.4.31
DOI:
10.4238/2014.December.4.31
Plant Genetics   Research Article

Genetic-molecular characterization of backcross generations for sexual conversion in papaya (Carica papaya L.)

Authors: H.C.C. Ramos1, M.G. Pereira1, T.N.S. Pereira1, G.B.A. Barros1 and G.A. Ferreguetti2

The low number of improved cultivars limits the expansion of the papaya crop, particularly because of the time required for the development of new varieties using classical procedures. Molecular techniques associated with conventional procedures accelerate this process and allow targeted improvements. Thus, we used microsatellite markers to perform geneti.. Read More»

Genet. Mol. Res. 13(4):
2014.December.4.32
DOI:
10.4238/2014.December.4.32
Plant Genetics   Research Article

Association between CYP1A1m1 gene polymorphism and primary open-angle glaucoma

Authors: N.B. Costa, C.T.X. Silva, A.B. Frare, R.E. Silva and K.K.V.O. Moura

The CYP1A1 gene is related to the generation of secondary metabolites that are capable of inducing DNA damage. The CYP1A1m1 polymorphism has been examined in many studies, and is located in a region near loci that have been linked to glaucoma, including the locus GLC1I. As a result, this polymorphism has been related to several diseases that are influence.. Read More»

Genet. Mol. Res. 13(4):
2014.December.4.33
DOI:
10.4238/2014.December.4.33
Plant Genetics   Research Article

Microsatellite in Aeschynomene falcata (Leguminosae): diversity, cross-amplification, and chromosome localization

Authors: C.A. Polido1,3, C.C. Mantello2, A.P. Moraes1,4, A.P. Souza1,2 and E.R. Forni-Martins1

Aeschynomene falcata is an important forage species; however, because of low seed production, it is underutilized as forage species. Aeschynomene is a polyphyletic genus with a challenging taxonomic position. Two subgenera have been proposed, and it is suggested that Aeschynomene can be split in 2 genera... Read More»

Genet. Mol. Res. 13(4):
2014.December.4.34
DOI:
10.4238/2014.December.4.34