Association between CYP1A1m1 gene polymorphism and primary open-angle glaucoma
Authors: N.B. Costa, C.T.X. Silva, A.B. Frare, R.E. Silva and K.K.V.O. Moura
The CYP1A1 gene is related to the generation of secondary metabolites that are capable of inducing DNA damage. The CYP1A1m1 polymorphism has been examined in many studies, and is located in a region near loci that have been linked to glaucoma, including the locus GLC1I. As a result, this polymorphism has been related to several diseases that are influence.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.December.4.33
- DOI:
- 10.4238/2014.December.4.33
Microsatellite in Aeschynomene falcata (Leguminosae): diversity, cross-amplification, and chromosome localization
Authors: C.A. Polido1,3, C.C. Mantello2, A.P. Moraes1,4, A.P. Souza1,2 and E.R. Forni-Martins1
Aeschynomene falcata is an important forage species; however, because of low seed production, it is underutilized as forage species. Aeschynomene is a polyphyletic genus with a challenging taxonomic position. Two subgenera have been proposed, and it is suggested that Aeschynomene can be split in 2 genera... Read More»
- Genet. Mol. Res. 13(4):
- 2014.December.4.34
- DOI:
- 10.4238/2014.December.4.34
S100A4 expression and prognosis of gastric cancer: a meta-analysis
Authors: Y. Wang1*, L.-B. Zhou1* and X.-H. Li2
The prognostic role of S100A4 in gastric cancer is still under debate. The present meta-analysis aimed to evaluate the relationship between S10A4 levels and the prognosis of gastric cancer. We performed a meta-analysis of published studies assessing the relationship between S100A4 and gastric cancer prognosis. We used the Revman 5.0 software to perform li.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.December.12.1
- DOI:
- 10.4238/2014.December.12.1
Genetic identification of Theobroma cacao L. trees with high Criollo ancestry in Soconusco, Chiapas, Mexico
Authors: J.A. V�¡zquez-Ovando1,4, F. Molina-Freaner2, J. Nu�±ez-Farf�¡n3, I. Ovando-Medina4 and M. Salvador-Figueroa4
Criollo-type cacao trees are an important pool of genes with potential to be used in cacao breeding and selection programs. For that reason, we assessed the diversity and population structure of Criollo-type trees (108 cultivars with Criollo phenotypic characteristics and 10 Criollo references) using 12 simple sequence repeat (SSR) markers. Cultivars were.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.December.12.2
- DOI:
- 10.4238/2014.December.12.2
Genetic divergence among sweet corn lines estimated by microsatellite markers
Authors: A.D. Lopes1, C.A. Scapim2, C.A. Mangolin3 and M.F.P.S. Machado3
The purpose of this study was to analyze the genetic diversity of 15 sugary-1 sweet corn lines by microsatellite markers. One hundred pairs of simple sequence repeat primers that were mapped for field corn were tested. Of these primers, 15% were polymorphic, and all were selected for the evaluation. These primers identified a total of 39 alleles among the.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.December.12.3
- DOI:
- 10.4238/2014.December.12.3
Gender difference in protein expression of vascular wall in mice exposed to chronic intermittent hypoxia: a preliminary study
Authors: Q.Y. Li1*, Y. Feng1*, Y.N. Lin1, M. Li1, Q. Guo1,2, S.Y. Gu1,3, J.L. Liu1, R.F. Zhang1,4 and H.Y. Wan1
Obstructive sleep apnea (OSA) is an independent risk factor for cardiovascular diseases such as systemic arterial hypertension, ischemic heart disease, stroke, heart failure, atrial fibrillation, and cardiac sudden death. The pathogenesis of cardiovascular disease in OSA is thought to be induced primarily by chronic intermittent hypoxia (CIH), a specific .. Read More»
- Genet. Mol. Res. 13(4):
- 2014.October.20.25
- DOI:
- 10.4238/2014.October.20.25
Bioinformatic analysis of miRNA expression patterns in TFF2 knock-out mice
Authors: Y. Yin, H.Q. Shan, W. Huang, Y.M. Wu, H. Lu and Y. Jin
Trefoil factors, which bear a unique 3-loop trefoil domain, are a family of small secretory protease-resistant peptides (7-12 kDa) discovered in the 1980s. Trefoil factor 2 (TFF2) is a unique member of trefoil factors family that plays important roles in gastrointestinal mucosal defense and repair. However, few studies have characterized the miRNA express.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.October.20.26
- DOI:
- 10.4238/2014.October.20.26
Roles of beta2-adrenergic receptor gene polymorphisms in a Turkish population with obstructive sleep apnea syndrome or obesity
Authors: �°. G�¶k1, �°. ��elebi2, N. H�¼seyino��lu3 and C. ��zic1
We determined the distribution of the Arg16Gly and Gln27Glu polymorphisms of the beta-2 adrenergic receptor gene (ADRB2) in patients with obstructive sleep apnea syndrome as well as a control group in Northeastern Turkey. A total of 52 patients diagnosed with obstructive sleep apnea in a sleep laboratory and 78 control subjects were examined. Peripheral b.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.October.20.27
- DOI:
- 10.4238/2014.October.20.27
Prediction of potential novel microRNAs in soybean when in symbiosis
Authors: G.A. Barros-Carvalho1,2, A.R. Paschoal3, F.C. Marcelino-Guimar�£es1 and M. Hungria1
MicroRNAs (miRNAs) are small molecules, noncoding proteins that are involved in many biological processes, especially in plants; among these processes is nodulation in the legume. Biological nitrogen fixation is a key process, with critical importance to the soybean crop. This study aimed to identify the potential of novel miRNAs to act during the root no.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.October.20.28
- DOI:
- 10.4238/2014.October.20.28
Combining ability for yield and fruit quality in the pepper Capsicum annuum
Authors: N.F.F. do Nascimento, E.R. do R�ªgo, M.F. Nascimento, C.H. Bruckner, F.L. Finger and M.M. do R�ªgo
The objective of this study was to determine the effects of the general and specific combining abilities (GCA and SCA, respectively) of 15 characteristics and to evaluate the most promising crosses and the reciprocal effect between the hybrids of six parents of the Capsicum annuum species. Six parents, belonging to the Horticu.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.29.2
- DOI:
- 10.4238/2014.April.29.2