Correlation between the NPPB gene promoter c.-1298 G/T polymorphism site and pulse pressure in the Chinese Han population
Authors: K. Zeng, X.D. Wu, H.D. Cai, Y.G. Gao, G. Li , Q.C. Liu, F. Gao, J.H. Chen and C.Z. Lin
The aim of this study was to investigate the correlation between the natriuretic peptide precursor B (NPPB) gene single nucleotide polymorphism (SNP) c.-1298 G/T and pulse pressure (PP) of the Chinese Han population and the association between genotype and clinical indicators of hypertension. Peripheral blood was collected fro.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.29.4
- DOI:
- 10.4238/2014.April.29.4
Molecular genetic diversity and maternal origin of Chinese black-bone chicken breeds
Authors: W.Q. Zhu, H.F. Li, J.Y. Wang, J.T. Shu, C.H. Zhu, W.T. Song, C. Song, G.G. Ji and H.X. Liu
Chinese black-bone chickens are valued for the medicinal properties of their meat in traditional Chinese medicine. We investigated the genetic diversity and systematic evolution of Chinese black-bone chicken breeds. We sequenced the DNA of 520 bp of the mitochondrial cyt b gene of nine Chinese black-bone chicken breeds, includ.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.29.5
- DOI:
- 10.4238/2014.April.29.5
Risk factors for the development of essential hypertension in a Mongolian population of China: a case-control study
Authors: N. Dalai, H. Cui, M. Yan, G. Rile, S. Li and X. Su
Lifestyle, habits, diet, and genetics are all important factors associated with the prevalence of hypertension. Many association studies have been performed in the Chinese Han population, whereas data explaining the high prevalence of hypertension in the Mongolian population remain scarce. In the present study, we aimed to det.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.29.6
- DOI:
- 10.4238/2014.April.29.6
Genetic polymorphisms of paraoxonase1 192 and glutathione peroxidase1 197 enzymes in familial Mediterranean fever
Authors: F. ��ktem, H. An�±l, R. S�¼tc�¼ and A.E. Kuybulu
Familial Mediterranean fever (FMF) is an autosomal recessive disorder and is the most frequent of the periodic febrile inflammatory syndromes. The pathogenesis of the disease is not completely understood, even though the FMF gene has been identified. Oxidative stress and inflammation may play a role in the pathogenesis of FMF... Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.29.7
- DOI:
- 10.4238/2014.April.29.7
Isolation and characterization of microsatellite DNA loci for wild Brassica juncea (Brassicaceae)
Authors: Y. Li1, X.Q. Sun2, Q.Q. Yan2, J.L. Guo2, S. Qiang1, X.L. Song1 and M.M. Li2
Wild Brassica juncea is a widespread weed in China with increasingly great impact on the yield of many crops. This study aimed to develop microsatellite markers for assessing the genetic diversity and population genetic structure of B. juncea, and to provide basic information for biological and chemical control of the weed. The compound microsatellite mar.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.8.1
- DOI:
- 10.4238/2013.November.8.1
Genetic relationship among Labisia pumila (Myrsinaceae) species based on ISSR-PCR
Authors: E. Karimi, H.Z.E. Jaafar, M.A. Aziz, S. Taheri and R. AzadiGonbad
The genus Labisia (Myrsinaceae) is a popular medicinal plant in Malaysia. We examined the genetic relationship among three varieties of L. pumila var. pumila, L. pumila var. alata, L. pumila var. lanceolata and Labisia paucifolia using an ISSR assay. Fifty-eight primers were tested, among which 18 gave reliable polymorphic ban.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.29.8
- DOI:
- 10.4238/2014.April.29.8
Association of xeroderma pigmentosum group D (Asp312Asn, Lys751Gln) and cytidine deaminase (Lys27Gln, Ala70Thr) polymorphisms with outcome in Chinese non-small cell lung cancer patients treated with cisplatin-gemcitabine
Authors: M. Zhou, Y.J. Ding, Y. Feng, Q.R. Zhang, Y. Xiang and H.Y. Wan
Xeroderma pigmentosum group D (XPD) plays a key role in the repair of DNA and platinum resistance lesions. Cytidine deaminase (CDA) genes determine the velocity of gemcitabine catalysis. This study aimed to investigate the relationship between XPD and CDA genotypes and outcome in non-small lung cancer (NSCLC) patients. We used.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.29.9
- DOI:
- 10.4238/2014.April.29.9
Experimental evaluation of the reproductive quality of Africanized queen bees (Apis mellifera) on the basis of body weight at emergence
Authors: D.A. De Souza1, M.A.F. Bezzera-Laure1, T.M. Francoy2 and L.S. Gon�§alves3,4
There has been much speculation about which phenotypic traits serve as reliable indicators of productivity in queen honeybees (Apis mellifera). To investigate the predictive value of queen body weight on colony development and quality, we compared colonies in which queens weighed less than 180 mg to those in which queens weighed more than 200 mg. Both gro.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.7.13
- DOI:
- 10.4238/2013.November.7.13
Comparison of methods for high quantity and quality genomic DNA extraction from raw cow milk
Authors: T. Usman, Y. Yu, C. Liu, Z. Fan and Y. Wang
Isolation of sufficient quantities of high quality DNA is a prerequisite for molecular studies. Milk somatic cells can be used; however, inhibitors such as fats and proteins make milk a difficult medium for extracting large amounts of quality DNA. We optimized, evaluated and compared three methods, Modified Nucleospin Blood Ki.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.29.10
- DOI:
- 10.4238/2014.April.29.10
Adjacent SNPs in the transcriptional regulatory region of the FADS2 gene associated with fatty acid and growth traits in chickens
Authors: S.K. Zhu, Y.D. Tian, S. Zhang, Q.X. Chen, Q.Y.Wang,R.L. Han and X.T. Kang
Delta-6 fatty acid desaturases are rate-limiting desaturases involved in metabolic processes of fatty acids, and they are encoded by the FADS2 gene. In the current study, an F2 resource population of Gushi chickens crossed with Anak broilers was used to investigate the genetic effects of the chicken FADS2. Two adjacent single .. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.29.11
- DOI:
- 10.4238/2014.April.29.11