Association of endothelin-1 gene polymorphisms with essential hypertension in a Chinese population
Authors: Z. Fang, M. Li, Z. Ma and G. Tu
Endothelin-1 (ET-1) is the most potent endogenous vasoconstrictor and is involved in several vascular disorders such as hypertension. Its strong interaction with other vasoactive hormone systems suggests that the ET-1 gene (EDN1) is a potential candidate molecule that influences the risk of developing hypertension. Recently, t.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16037446
- DOI:
- 10.4238/gmr16037446
Identification of Colletotrichum isolates from Capsicum chinense in Amazon
Authors: C.V.S. de Oliveira, K.S. Matos, D.M.C. de Albuquerque, R.E. Hanada and G.F. da Silva
Chili pepper (Capsicum chinense) is a great economic important culture on the State of Amazonas, and it represents, approximately, a production of 1.9 thousand tons per year. It is one of the hosts of Colletotrichum genus in the North region of Brazil. The aim of the study was to differentiate and to identify isolates of Colle.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029601
- DOI:
- 10.4238/gmr16029601
Promoter identification and analysis of key glycosphingolipid biosynthesis-globo series pathway genes in piglets
Authors: W.Y. Qin, L.N. Gan, R.W. Xia, W.H. Dong, S.Y. Sun, G.Q. Zhu,S.L. Wu and W.B. Bao
Glycosphingolipid biosynthesis-globo series pathway genes (FUT1, FUT2, ST3GAL1, HEXA, HEXB, B3GALNT1, and NAGA) play an important regulatory role in the defense against Escherichia coli F18 in piglets. In this study, we identified the transcription initiation site and promoter of this gene cluster by mined previous RNA-seq res.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029574
- DOI:
- 10.4238/gmr16029574
Identification and characterization of the bZIP transcription factor involved in zinc homeostasis in cereals
Authors: A.R. Henriques, D. da R. Farias and A. Costa de Oliveira
Members of the basic leucine zipper family, as bZIP19, are considered to be essential regulators of the adaptation to zinc deficiency. Knowing that this gene as well as its targets are conserved in the plant kingdom, we followed an in silico approach to identify and characterize the bzip19 gene in cereals. Through BLASTp in Ph.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029558
- DOI:
- 10.4238/gmr16029558
Artificial neural networks as auxiliary tools for the improvement of bean plant architecture
Authors: V.Q. Carneiro, G.N. Silva, C.D. Cruz, P.C.S Carneiro, M. Nascimento and J.E.S. Carneiro
lassification using a scale of visual notes is a strategy used to select erect bean plants in order to improve bean plant architectures. Use of morphological traits associated with the phenotypic expression of bean architecture in classification procedures may enhance selection. The objective of this study was to evaluate the .. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029500
- DOI:
- 10.4238/gmr16029500
Mechanism of reversal of multidrug resistance by curcumin in human colorectal cancer cell line HCT-8/5-FU
Authors: Y.X. Fan, P. Abulimiti, H.L. Zhang, Y.K. Zhou and L. Zhu
Since there are no studies on the reversal of multidrug resistance by curcumin in the human colorectal cancer cell line HCT-8/5-FU, our aim was to search for highly efficient reversal agents and investigate the underlying mechanisms of this reversal. The cytotoxic effects of curcumin and 5-FU on HCT-8 and HCT-8/5-FU cells and .. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029414
- DOI:
- 10.4238/gmr16029414
Generic relationships among Molluginaceae inferred from a molecular phylogenetic analysis of the matK gene
Authors: M.A. Ali, J. Lee and F. Al-Hemaid
The family Molluginaceae (order Caryophyllales) is considered polyphyletic based on the photosynthetic pathway, C4 evolution, and phylogeny of the family. This inference was made based on photosynthetic, anatomical, and molecular datasets. The generic circumscription of this family has greatly been changed owing to the placeme.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029295
- DOI:
- 10.4238/gmr16029295
Genetic variability among elite popcorn lines based on molecular and morphoagronomic characteristics
Authors: J.F. dos Santos, C.A. Mangolin, M.F.P.S. Machado, C.A. Scapim, W. Giordani and L.S.A. Gon�§alves
Knowledge of genetic diversity among genotypes and relationships among elite lines is of great importance for the development of breeding programs. Therefore, the objective of this study was to evaluate genetic variability based on the morphoagronomic and molecular characterization of 18 elite popcorn (Zea mays var. everta) li.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029243
- DOI:
- 10.4238/gmr16029243
Genetic correlation and genome-wide association study (GWAS) of the length of productive life, days open, and 305-days milk yield in crossbred Holstein dairy cattle
Authors: P. Saowaphak, M. Duangjinda, S. Plaengkaeo, R. Suwannasing and W. Boonkum
In this study, we estimated the genetic parameters and identified the putative quantitative trait loci (QTL) associated with the length of productive life (LPL), days open (DO), and 305-day milk yield for the first lactation (FM305) of crossbred Holstein dairy cattle. Data comprising 4,739 records collected between 1986 and 20.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029091
- DOI:
- 10.4238/gmr16029091
Comparison of physical and chemical characteristics of collagen from the skin of cod (Gadus macrocephaius)
Authors: Y. Shu, H. Ren, R. Ao, W.C. Qi and Z.S. Zhang
Acid and pepsin-soluble collagen (ASC and PSC, respectively) were extracted from cod (Gadus macrocephaius) skin, and yields of 37.36 and 55.96% were obtained for ASC and PSC, respectively. The total yield of ASC and PSC was 93.92%, based on the lyophilized dry weight, which is higher than that obtained from other sources. Elec.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16027940
- DOI:
- 10.4238/gmr16027940