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Plant Genetics   Research Article

Environmental stratifications for soybean cultivar recommendation and its consistency over time

Authors: R.M. Pacheco, J.B. Duarte, R.G. Branquinho and P.I.D.M. Souza

Stratification of environments is a strategy to capitalize genotype x environment (GxE) interaction, which can optimize the process of assessment and cultivar recommendation, increasing productivity in a target environmental population. The objective of this study was to assess environmental stratification methods based on the.. Read More»

Genet. Mol. Res. 16(3):
gmr16039693
DOI:
10.4238/gmr16039693
Human Genetics   Research Article

Mitochondrial DNA control region analysis of three ethnic populations in lower Northern part of Thailand

Authors: U. Suyasunanont, M. Nakkuntod and S. Mirasena

The lower northern part of Thailand contains various genetically diverse ethnic populations. The sequences of the mitochondrial DNA hypervariable region were studied in three ethnic populations inhabiting Phitsanulok Province. One hundred and nine nucleotide sequences - 53, 29, and 27 from Hmongs (Hill tribe), Lao Songs, and T.. Read More»

Genet. Mol. Res. 16(3):
gmr16039687
DOI:
10.4238/gmr16039687
Animal Genetics   Research Article

Alteration of -656(G/T) and -607(C/A) polymorphisms in interleukin-18 (IL-18) gene in house dust mite-sensitive allergic rhinitis patients in Thailand

Authors: A. Tungtrongchitr, J. Jumpasri, N. Sookrung, N. Visitsunthorn, P. Tantilipikorn, O. Piboonpocanan, N. Indrawattana, R. Tungtrongchitr and W. Chaicumpa

Allergic rhinitis (AR) is an IgE-mediated inflammation of the nasal membranes, which is naturally triggered by aeroallergens. House dust mites (HDM) are the most common inhalant allergens. Interleukin-18 (IL-18) has been established as an essential cytokine that can activate the generation of IgE. This randomized controlled st.. Read More»

Genet. Mol. Res. 16(3):
gmr16039641
DOI:
10.4238/gmr16039641
Human Genetics   Research Article

Molecular analysis of the GSTT1 gene polymorphism in patients with clinical manifestation of atherosclerosis

Authors: J.V.M. Martins, D.A. Rodrigues, K.S.F. Silva, I.R. Costa, M.H. Lagares, F.L. Campedelli, A.M. Barbosa, M.P. Morais and K.K.V.O. Moura

Atherosclerosis is a chronic inflammatory disease formed by the accumulation of lipids in the innermost layer and large-caliber artery (tunica intima). This accumulation, along with platelet factors, stimulates the proliferation of muscle cells in this region. Over than 400 genes may be related to the pathology since they regu.. Read More»

Genet. Mol. Res. 16(3):
gmr16039620
DOI:
10.4238/gmr16039620
Animal Genetics   Research Article

Bayesian analyses of genetic parameters for growth traits in Nellore cattle raised on pasture

Authors: F.B. Lopes, J.L. Ferreira, R.B. Lobo and G.J.M. Rosa

This study was carried out to investigate (co)variance components and genetic parameters for growth traits in beef cattle using a multi-trait model by Bayesian methods. Genetic and residual (co)variances and parameters were estimated for weights at standard ages of 120 (W120), 210 (W210), 365 (W365), and 450 days (W450), and f.. Read More»

Genet. Mol. Res. 16(3):
gmr16039606
DOI:
10.4238/gmr16039606
Human Genetics   Research Article

Improvement in orthopedic outcome score and reduction in IL-1�², CXCL13, and TNF-�± in synovial fluid of osteoarthritis patients following arthroscopic knee surgery

Authors: Z.M. Li and M. Li

Knee osteoarthritis (KOA) is a common degenerative joint disease and immune system dysregulation has been implicated in its pathogenesis. The effect of arthroscopic knee surgery, an important method for KOA diagnosis and treatment, on the expression of immune regulators remains poorly understood. We aimed to investigate the cl.. Read More»

Genet. Mol. Res. 16(3):
gmr16039487
DOI:
10.4238/gmr16039487
Plant Genetics   Research Article

Selection of maize inbred lines and gene expression for resistance to ear rot

Authors: G.S. Pereira, R.G.V. Pinho, E.V.R.V. Pinho, L.P.M. Pires, L.A.Y. Bernardo Junior, J.L.A. Pereira and M.P. Melo

In recent years, there has been a large incidence of fungi causing “ear rot” in maize in Brazil, the main fungus being Fusarium verticillioides. The most efficient and competitive alternative for control of this disease consists of using maize hybrids resistant to this pathogen. Thus, the aims of this study were to.. Read More»

Genet. Mol. Res. 16(3):
gmr16039415
DOI:
10.4238/gmr16039415
Human Genetics   Research Article

Clinical significance and expression of PUMA, MCL-1, and p53 in human renal cell carcinoma and para-carcinoma tissues

Authors: H.B. Xia, H.W. Cui, L. Su, Z.H. Zhang, X.Y. Yang, S.Q. Ning and X.L. Su

We investigated the expression level of p53 upregulated modulator of apoptosis (PUMA), myeloid cell leukemia-I (MCL-1), and p53 in renal cell carcinoma (RCC) and para-carcinoma tissues, as well as their clinical significance. The expression levels of PUMA, MCL-1, and p53 in RCC and para-carcinoma tissues were measured using im.. Read More»

Genet. Mol. Res. 16(3):
gmr16039278
DOI:
10.4238/gmr16039278
Plant Genetics   Research Article

Variability among Capsicum baccatum accessions from Goi�¡s, Brazil, assessed by morphological traits and molecular markers

Authors: A.L.A. Martinez, J.S.P. Ara�ºjo, C.F. Ragassi, G.S.C. Buso and F.J.B. Reifschneider

Capsicum peppers are native to the Americas, with Brazil being a significant diversity center. Capsicum baccatum accessions at Instituto Federal (IF) Goiano represent a portion of the species genetic resources from central Brazil. We aimed to characterize a C. baccatum working collection comprising 27 accessions and 3 commerci.. Read More»

Genet. Mol. Res. 16(3):
gmr16039074
DOI:
10.4238/gmr16039074
Plant Genetics   Research Article

An optimized protocol for DNA extraction in plants with a high content of secondary metabolites, based on leaves of Mimosa tenuiflora (Willd.) Poir. (Leguminosae)

Authors: S.R. Arruda, D.G. Pereira, M.M. Silva-Castro, M.G. Brito and A.M. Waldschmidt

Some species are characterized by a high content of tannins, alkaloids, and phenols in their leaves. These secondary metabolites are released during DNA extraction and might hinder molecular studies based on PCR (polymerase chain reaction). To provide an efficient method to extract DNA, Mimosa tenuiflora, an important legumino.. Read More»

Genet. Mol. Res. 16(3):
gmr16039063
DOI:
10.4238/gmr16039063