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Human Genetics   Research Article

Bell’s palsy following growth hormone therapy in a patient with Prader-Willi syndrome: The first report

Authors: Setila Dalili, Elham Bidabadi, Babak Behnam

Prader–Willi syndrome (PWS) is a complex genetic disorder with different manifestations in infancy and childhood including obesity, type 2 diabetes mellitus, mild to moderate intellectual impairment and learning disabilities. In this syndrome, growth hormone therapy improves outcomes. For the first time, here we report a.. Read More»

Genet. Mol. Res. 17(1):
gmr16039877
DOI:
10.4238/gmr16039877
Plant Genetics   Research Article

Characterization of gametophytic self-incompatibility of superior clones of Coffea canephora

Authors: M.S. Moraes, A.L. Teixeira, A.R. Ramalho, M.C. Esp?­ndula, M.A.G Ferr?£o and R.B. Rocha

The ability to avoid self-pollination is a trait that evolved as a manner of reducing the deleterious effects of inbreeding in various allogamous plant species, including Coffea canephora. The aim of this study was to perform directed hybridizations to characterize the compatibility groups of superior C. canephora clones, sinc.. Read More»

Genet. Mol. Res. 17(1):
gmr16039876
DOI:
10.4238/gmr16039876
Plant Genetics   Research Article

New insights into the genetic diversity and species identification of the native apricots in Southern Xinjiang of China

Authors: Ling Guo, Hui Li, Zheng-rong Luoa

Apricot is a staple stone fruit crop cultivated in Southern Xinjiang of China. This crop is important for the rural communities, as they generate significant employment and income. Here, seventy-eight apricot genotypes, including seventy-six common apricots (Prunus armeniaca L.) and two purple apricots (Prunus dasycarpa Ehrh.).. Read More»

Genet. Mol. Res. 17(1):
gmr16039874
DOI:
10.4238/gmr16039874
Human Genetics   Short communication

Role of KRAS in NSCLC: present and future

Authors: Addeo A, Bini R

Lung cancer is the leading cause of cancer-related deaths worldwide. Despite therapeutic advances over the last several decades, the overall 5-year survival remains only 16%. (Siegel R, 2013). Molecular studies have indicated that Adenocarcinomas have distinct genomic alterations allowing classification into clinically relevan.. Read More»

Genet. Mol. Res. 17(1):
gmr16039873
DOI:
10.4238/gmr16039873
Medical Genetics   Research Article

Anthocyanins-loaded Eudragit?® L100 nanoparticles: in vitro cytotoxic and genotoxic analysis

Authors: TB de Queiroz, D Dupeyr?³n, JCT Carvalho, IOM Gaiv?£o, and EL Maistro

Anthocyanins are flavonoids compounds that have a great therapeutic potential acting as antioxidants, anti-inflammatory and anti-carcinogenic agents. They are consumed through food, pharmaceutical and cosmetics industries as a natural alternative to synthetic dyes. However, anthocyanins are unstable depending on pH, temperatur.. Read More»

Genet. Mol. Res. 17(1):
gmr16039875
DOI:
10.4238/gmr16039875
Plant Genetics   Review Article

Hierarchical outcrossing among and within fruits in Bertholletia excelsa Bonpl. (Lecythidaceae) open-pollinated seeds

Authors: L.D. Giustina, A.B. Baldoni, H. Tonini, V.C.R. Azevedo, L.G. Neves, F.D. Tardin, A.M. Sebbenn

Knowing the mating patterns is important to determine the number of trees necessary for seed collection for conservation ex situ, tree breeding and environmental reforestation purposes. We investigated B. excelsa individuals and fruits, to check mating system index variations in a population by using open-pollinated seeds whic.. Read More»

Genet. Mol. Res. 17(1):
gmr16039872
DOI:
10.4238/gmr16039872
Plant Genetics   Research Article

Molecular Characterization and Differential Interaction of Xanthomonas axonopodis pv. phaseoli and Xanthomonas fuscans subsp. fuscans with Common Beans (Phaseolus vulgaris)

Authors: De Paiva BAR, Wendland A , Borba TC , Ara?ºjo LG

The common bacterial blight, caused by Xanthomonas axonopodis pv. phaseoli (Xap) and X. fuscans subsp. fuscans (Xff), is one of the most important dry bean diseases of bacterial etiology. The present work aimed to study the genetic structure among and within populations, and also identify the pathogenic variability of Xap and .. Read More»

Genet. Mol. Res. 17(1):
gmr16039871
DOI:
10.4238/gmr16039871
Plant Genetics   Research Article

Genetic diversity assessment of Allium cepa L. cultivars from Bosnia and Herzegovina using SSR makers

Authors: Lutvija Kari??, Maryam Golzardi, Petar Glamo?lija, Jasmin ? utkovi??

The five most common cultivars from the genus Allium cepa L. in Bosnia and Herzegovina (BiH) were analysed, focusing on Konjic onion. Seven SSR markers for genetic similarity analysis were used to address the genetic backgrounds. The polymorphic relationship between the SSR markers was analyzed by using Polymorphic Informatio.. Read More»

Genet. Mol. Res. 17(1):
gmr16039870
DOI:
10.4238/gmr16039870
Plant Genetics   Research Article

Determination of the number of harvests to select elite sugarcane genotypes in NE Brazil

Authors: J.A. Dutra Filho, T.C. Junior, D. E. Simoes Neto, L. S. Souto, Romulo Gil de Luna A.S. Souza

Sixty-eight sugarcane genotypes were evaluated to determine the number of harvests required to select new genotypes in the sugarcane belt in the state of Pernambuco, northeast Brazil. Using a random block design, the following parameters were evaluated: (i) polarizable sugars (POL) per hectare, in metric tons (TPH); (ii) culm .. Read More»

Genet. Mol. Res. 17(1):
gmr16039869
DOI:
10.4238/gmr16039869
Animal Genetics   Research Article

Effect of genetic polymorphism of ?±S1- casein gene on qualitative and quantitative milk traits in native Bulgarian Rhodopean cattle breed

Authors: J Peter Hristov, Denitsa Teofanova, Ani Georgieva, Georgi Radoslavov

Milk protein genetic polymorphisms of the genus Bos provoke a significant scientific interest, mainly associated with their evolution, population structure, breeding and hybridization. The aim of present study is to investigate the influence of the genetic variants of αS1- casein gene with respect to milk production and .. Read More»

Genet. Mol. Res. 17(1):
gmr16039868
DOI:
10.4238/gmr16039868