Predominance of the A allele but no association of the KCNJ11 rs5219 E23K polymorphism with Type 2 Diabetes in a Nigerian population
Authors: Godwill Azeh Engwa, Friday Nweke Nwalo, Chosen E. Obi, Christie Onyia, Opeolu Oyejide Ojo Wilfred Fon Mbacham, Benjamin Ewa Ubi
Though the rs5219 E23K variant of the KCNJ11 gene is commonly known to be associated with Type 2 diabetes (T2D) in Caucasian and Asian populations, little or none of such findings have been revealed in Nigeria. Hence, this study was aimed to assess the relationship between E23K polymorphic variant of the KCNJ11 gene and T2D in.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039889
- DOI:
- 10.4238/gmr16039889
The Disruption of Klf6-Related Super-Enhancer Induces Growth Inhibition and Apoptosis in Human HepG2 Cells
Authors: KumChol Ri, KumChol Kim, SunHyok Kong, JuHua Ri
Klf6 is a member of the Krüppel-like factor family, which is a group of zinc finger transcription factors involved in differentiation and development. In general, Klf6 gene plays an important role in growth-related signal transduction pathways, cell proliferation, apoptosis, and angiogenesis. Recently, the Klf6 gene is co.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039888
- DOI:
- 10.4238/gmr16039888
Estimate of natural cross-pollination rate of Capsicum annuum using a codominant molecular marker associated with fruit pungency
Authors: EV Justino, MEN Fonseca, ME Ferreira, LS Boiteux, PP Silva, WM Nascimento
The production of seeds with high genetic quality requires accurate estimates of the natural cross-pollination rate in cultivated Capsicum species. This is important in order to establish the most suitable isolation distance among fields of distinct genotypes, to minimize the risk of genetic contamination and to ensure that th.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039887
- DOI:
- 10.4238/gmr16039887
Marker-Assisted elimination of drought-susceptible accessions in upland rice breeding
Authors: Ariadna Faria Vieira, Gabriel Feresin Pantali�£o, Fernanda Martins Abreu, Ricardo Dias Silveira, Ana Letycia Basso Garcia, Leandro Gomide Neves, Rosana Pereira Vianello, Adriano Pereira Castro, Claudio Brondani
Breeding for water-deficit tolerance is fundamental to guarantee the sustainability of upland rice production, mainly due to the possibility of an increased frequency of drought episodes due to climate change. This work aimed to identify single nucleotide polymorphism (SNP) markers, derived from RNA sequencing (RNA-Seq), genom.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039886
- DOI:
- 10.4238/gmr16039886
Lentinus crinitus strains respond differently to cultivation pH and temperature
Authors: R.A. Marim, K.V. Avelino, G.A. Linde, N.B. Colauto and J.S. Valle
Fungus ability to respond to environmental changes allows their adaptation to a wide variety of conditions such as pH, temperature, light, nutrient availability, chemicals, and competition among species. Temperature and pH can affect fungal growth as well as their metabolism. Knowing these factors on fungus species is relevant.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039885
- DOI:
- 10.4238/gmr16039885
Effect of food intake on biomarkers for cardiovascular disease and inflammation analyzed with the Proseek Multiplex CVD II kit
Authors: Magnus Dencker, Ylva G�¥rdinger, Ola Bj�¶rgell, Joanna Hlebowicz
Objectives: The present study evaluates the effect of food intake on 90 biomarkers for cardiovascular disease (CVD) and inflammation with the Proseek Multiplex CVD II kit. Methods: Twenty-two healthy subjects (11 male and 11 females aged 25.9±4.2 years) were investigated. A total of 90 biomarkers were measured before a .. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039884
- DOI:
- 10.4238/gmr16039884
Genetic diversity among accessions of Capsicum annuum L. through morphoagronomic characters
Authors: Angela Maria dos Santos Pessoa, Elizanilda Ramalho do R�ªgo, Michelle Gon�§alves de Carvalho, Cristine Agrine Pereira dos Santos, Mailson Monteiro do R�ªgo
Genetic variability among pepper genotypes is essential in obtaining hybrid combinations with greater heterotic effect and in obtaining superior strains. This work’s goal was to evaluate the genetic diversity between accessions of Capsicum annuum L., indicating the selection of promising individuals for ornamental purpos.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039883
- DOI:
- 10.4238/gmr16039883
Agronomic performance of plantain genotypes and genetic variability using Ward-MLM algorithm
Authors: Z. S. Gon�§alves, D. R. S. da Inven�§�£o, C. A. da S. Ledo, C. F. Ferreira, E. P. Amorim
Plantains in Brazil are produced from the `Terra Maranhão’, ‘Terrinha’ and ‘D´Angola’ cultivars, which are all susceptible to black Sigatoka, weevils and nematodes. Therefore, the development of resistant plantain cultivars with agronomic characteristics aligned with market demands i.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039882
- DOI:
- 10.4238/gmr16039882
Retrospective Investigation of Interleukin 1 and 6 Gene Polymorphism among Elderly Patients with Sarcopenia in the Turkish Population
Authors: Pinar Tosun Tasar
Introduction: Sarcopenia, one of the geriatric syndromes, is defined as generalized and progressive reduction in skeletal muscle mass accompanied by loss of muscle strength and/or function. There is a paucity of research in the Turkish population about the effects of interleukin 1 (IL-1) and IL-6 gene polymorphism on sarcopeni.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039881
- DOI:
- 10.4238/gmr16039881
Development and characterization of twenty-eight polymorphic microsatellite for rice field eel (Monopterus albus) using RAD tag sequencing
Authors: Feifei Zhang, Yulan Wang, Min Xu, Lili Wei, Qiwang Zhong
Monopterus albus is a special economic aquatic animal in China. Most of cultured M. albus are wild species captured from different areas, and this makes the wild resources of M. albus are under great threat. Microsatellite markers can help us understand the genetic resources of M. albus in different areas. In this study, using.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039880
- DOI:
- 10.4238/gmr16039880