Effect of miR-146a polymorphism on biochemical recurrence risk after radical prostatectomy in southern Chinese population

Authors: M. Chen, Z.Y. Zhou, J.G. Chen, N. Tong, S.Q. Chen, Y. Yang, X.W. Zhang, H. Jiang, N. Liu, J. Liu, G.Z. Sha, W.D. Zhu, L.X. Hua, Z.J. Wang and B. Xu

Evidence has shown that miR-146a is involved in carcinogenesis and a common G/C variant (rs2910164) in the pre-miR-146a gene has been found to be associated with various cancers. We investigated the potential prognostic role of miR-146a polymorphism in prostate cancer after radical prostatectomy... Read More»

Genet. Mol. Res. 13(4):

2014.December.18.3

DOI:

10.4238/2014.December.18.3

Intestinal lactic acid bacteria from Muscovy duck as potential probiotics that alter adhesion factor gene expression

Authors: Z.L. Xie, D.P. Bai, L.N. Xie, W.N. Zhang, X.H. Huang and Y.F. Huang

The purpose of this study was to assess the suitability of lactic acid bacteria (LABs) isolated from Muscovy duck as a potential probiotic. Isolates were identified by targeted polymerase chain reaction and assessed in vitro for probiotic characteristics such as autoaggregation; surface-charge; hydrophobicity; tolerance to aci.. Read More»

Genet. Mol. Res. 14(4):

2015.October.9.15

DOI:

10.4238/2015.October.9.15

Immunohistochemical expression of nestin in rhabdomyosarcoma: implications for clinicopathology and patient outcome

Authors: S. Glumac, S. Pejic, R. Kovacevic, D. Dundjerovic, R. Davidovic, D. Ristic and J. Sopta

Rhabdomyosarcoma (RMS) is a highly malignant cancer. Over the last two decades, prognosis for RMS patients has significantly improved, with the exception of those in the high-risk group. In order to identify new prognostic factors, we investigated the expression of nestin in RMS cells and its correlation with clinicopathological features and patient outco.. Read More»

Genet. Mol. Res. 14(4):

2015.November.18.29

DOI:

10.4238/2015.November.18.29

Haplo-block structure of Southern African village chicken populations inferred using genome-wide SNP data

Authors: K.S. Khanyile, E.F. Dzomba and F.C. Muchadeyi

This study investigated the haplo-block structure, haplotype sharing, and diversity in extensively raised chicken populations of Southern Africa. Two hundred ninety village chickens from Malawi (N = 30), South Africa (N = 132), and Zimbabwe (N = 128) were included in the study, from which 649, 2104, and 2442 haplo-blocks were .. Read More»

Genet. Mol. Res. 14(4):

2015.October.9.16

DOI:

10.4238/2015.October.9.16

Effect of NB-UVB on levels of MCP-1 and CCR6 mRNA in patients with psoriasis vulgaris

Authors: M.L. Gao and A.G. Wang

The aim of this study is to explore the effect of narrow band ultraviolet B (NB-UVB) on the chemokine receptor CCR6 mRNA levels in patients with psoriasis. Psoriasis area and severity index (PASI) values were recorded before and after the treatment with NB-UVB phototherapy of 30 psoriasis vulgaris patients. The reverse transcr.. Read More»

Genet. Mol. Res. 14(4):

2015.October.9.1

DOI:

10.4238/2015.October.9.1

Lack of association between the hOGG1 gene Ser326Cys polymorphism and gastric cancer risk: evidence from a case-control study anda meta-analysis

Authors: W.G. Hu, R.J. Pan, W. Cai, Z.T. Wang and Z.G. Zhu

The association between the human 8-oxoguanine glycosylase 1 (hOGG1) gene Ser326Cys polymorphism (rs1052133) and gastric cancer has been widely evaluated, yet a definitive answer to whether this association exists is lacking. We first conducted a case-control study to assess this association in a large Han Chinese population, and then performed a meta-ana.. Read More»

Genet. Mol. Res. 14(4):

2015.November.18.31

DOI:

10.4238/2015.November.18.31

Is there a relationship between polyploidy and stressful environments? A case study of inselbergs in northeastern Brazil

Authors: S.R. Pitrez, L.A. Andrade, F.N.M. Assis and L.P. Felix

The aim of this study was to examine the hypothesis that plants with higher ploidy levels are selected by environments under more extremely stressful conditions than the same (or closely related) species from less rigorous terrestrial or epiphytic habitats. Therefore, we analyzed the chromosome numbers of 26 species belonging to 21 genera and 13 families .. Read More»

Genet. Mol. Res. 13(4):

2014.October.20.11

DOI:

10.4238/2014.October.20.11

Effectiveness of bacterial infection-related cytokine profile (BIRCP) determination for monitoring pathogen infections in children with hemopathy in the bone marrow inhibition phase

Authors: X.D. Chen, B. Chen, Y.M. Tang, H. Song, S.W. Shi, S.L. Yang, W.Q. Xu, B.H. Pan, F.Y. Zhao, N. Zhao, L.Y. Zhang and J.Q. Mao

Genet. Mol. Res. 13(4):

Lack of association between the vitamin D receptor polymorphism rs2228570 and chronic periodontitis in a Han Chinese population

Authors: X. Wang, T.L. Zhang and D. Chen

The vitamin D receptor (VDR) is involved in the immune response and bone metabolism, both of which are implicated in the pathogenesis of chronic periodontitis (CP). In this study, we investigated the association between the VDR single nucleotide polymorphism rs2228570 and CP susceptibility in a Han Chinese population consistin.. Read More»

Genet. Mol. Res. 14(4):

2015.October.9.18

DOI:

10.4238/2015.October.9.18

Comparison of dimensionality reduction methods to predict genomic breeding values for carcass traits in pigs

Authors: C.F. Azevedo, M. Nascimento, F.F. Silva, M.D.V. Resende, P.S. Lopes, S.E.F. Guimar�£es and L.S. Gl�³ria

A significant contribution of molecular genetics is the direct use of DNA information to identify genetically superior individuals. With this approach, genome-wide selection (GWS) can be used for this purpose. GWS consists of analyzing a large number of single nucleotide polymorphism markers widely distributed in the genome; h.. Read More»

Genet. Mol. Res. 14(4):

2015.October.9.10

DOI:

10.4238/2015.October.9.10