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Human Genetics   Research Article
Atherosclerosis: analysis of the eNOS (T786C) gene polymorphism

Authors: A.M. Barbosa, K.S.F. Silva, M.H. Lagares, D.A. Rodrigues,I.R. da Costa, M.P. Morais, J.V.M. Martins, R.S. Mascarenhas, F.L. Campedelli and K.K.V.O. Moura

The coronary arteriosclerotic disease is the most common cardiovascular disease. Atherosclerosis affects large- and medium-sized arteries leading to severe thrombosis or artery stenosis that could evolve to myocardial infarction, ischemic stroke, ischemic injury of kidneys and intestines, and several other life-threatening cli.. Read More»

Genet. Mol. Res. 16(3): gmr16039708

DOI: 10.4238/gmr16039708

Plant Genetics   Research Article
A proteomic approach to guarana seed and pericarp maturation

Authors: A.L. Souza, J.L. Lopez-Losano, P.C.S. Angelo, J.N. Souza-Neto, I.B. Cordeiro, S. Astolfi-Filho and E.V. Andrade

Paullinia cupana Kunth var. sorbilis (Mart.) Ducke, the cultivated guarana plant, is native to the Amazon and has been valued for its medicinal, stimulant and energetic properties for centuries. The seeds are the main commercial product of the plant and the source of high amounts of purine alkaloids (caffeine and theobromine) .. Read More»

Genet. Mol. Res. 16(3): gmr16039642

DOI: 10.4238/gmr16039642

Animal Genetics   Research Article
A comparative study on genetic characteristics of two new varieties of Pelodiscus sinensis and their hybrid

Authors: H.Q. Zhang, X.J. Xu, Z.Y. He, J.Z. Shao, X.H. Zhang, Q.H. Meng and F.Y. Huang

Chinese soft-shelled turtle Pelodiscus sinensis has been an important aquaculture species in Southeast Asian countries. To breed a new variety of soft-shelled turtle with excellent properties and to evaluate the effect of hybridization of two turtle strains with a highly different trait phenotype, inheritance, microsatellite l.. Read More»

Genet. Mol. Res. 16(3): gmr16039148

DOI: 10.4238/gmr16039148

Plant Genetics   Research Article
Genetic effects of in vitro germination and plantlet development in chilli pepper

Authors: P.A. Barroso, M.M. R�ªgo, E.R. R�ªgo and K.T.C. Ferreira

The objective of this study was to estimate the genetic effects on in vitro germination and development of chili peppers. For this, four genotypes (UFPB-132, -134, -137, and -390) were used as parents. They were crossed in a complete diallel scheme. The parents (4) and hybrid (12) seeds were germinated in glass bottles contain.. Read More»

Genet. Mol. Res. 16(3): gmr16038869

DOI: 10.4238/gmr16038869

Microbial Genetics   Research Article
A RAPD-PCR-based genetic diversity analysis of Helicoverpa armigera and H. zea populations in Brazil

Authors: H.M. Lopes, C.S. Bastos, L.S. Boiteux, J. Foresti and F.A. Suinaga

Helicoverpa armigera is the most significant pest of agriculture in Asia, Europe, Africa, and Australasia, causing damage to crops greater than US$2 billion annually and until 2013 it was not detected in Brazil. Helicoverpa zea is restricted to the American continent and is important to corn and a secondary pest of cotton and .. Read More»

Genet. Mol. Res. 16(3): gmr16038757

DOI: 10.4238/gmr16038757

Human Genetics   Research Article
Clinical features of Mexican patients with Mucopolysaccharidosis type I

Authors: A. Alonzo-Rojo, J.E. Garc�­a-Ortiz, M. Ortiz-Aranda, M.P. Gallegos-Arreola and L.E. Figuera-Villanueva

Mucopolysaccharidosis type I (MPS-I) is an autosomal recessive lysosomal storage disorder caused by a deficiency or absence of α-l-iduronidase, which is involved in the catabolism of glycosaminoglycans (GAGs). This deficiency leads to the accumulation of GAGs in several organs. Given the wide spectrum of the disease, MPS.. Read More»

Genet. Mol. Res. 16(3): gmr16032602

DOI: 10.4238/gmr16032602

Bioinformatics   Research Article
Characterization of glucose-tolerant �²-glucosidases used in biofuel production under the bioinformatics perspective: a systematic review

Authors: D.C.B. Mariano, C. Leite, L.H.S. Santos, L.F. Marins, K.S. Machado, A.V. Werhli, L.H.F. Lima and R.C. de Melo-Minardi

β-glucosidases are enzymes that catalyze the hydrolysis of oligosaccharides and disaccharides, such as cellobiose. These enzymes play a key role in cellulose degrading, such as alleviating product inhibition of cellulases. Consequently, they have been considered essential for the biofuel industry. However, the majority of.. Read More»

Genet. Mol. Res. 16(3): gmr16039740

DOI: 10.4238/gmr16039740

Human Genetics   Research Article
Role of IL17A rs2275913 and rs3748067 polymorphisms in the risk cervical cancer

Authors: A.Q. Niu, Y.H. Cao, H. Wang, X. Zhang, B. Zhu and Z.H. Li

Cervical cancer is a serious public health problem and is associated with high cancer-related mortality in females worldwide. The expression of IL17A can increase the migration and invasiveness of cervical cancer cells by activating the NF-κB signal pathway. Single-nucleotide polymorphisms (SNPs) can alter gene function .. Read More»

Genet. Mol. Res. 16(3): gmr16038826

DOI: 10.4238/gmr16038826