Table of Contents | Genet. Mol. Res.2017(1)
Migration and invasion enhancer 1 (MIEN1) is overexpressed in breast cancer and is a potential new therapeutic molecular target
Authors: H.-B. Zhao, X.-F. Zhang, H.-B. Wang and M.-Z. Zhang
Migration and invasion enhancer 1 (MIEN1) is a membrane-anchored protein that is highly expressed in various types of cancer, and is correlated with the PI3K/AKT pathway. The aim of this study was to investigate the expression of MIEN1 and its clinical pathological significance in breast cancer. We used immunohistochemical sta.. Read More»
Genet. Mol. Res. 16(1): gmr16019380
DOI: 10.4238/gmr16019380
Complete mitochondrial genome of the Amur hedgehog Erinaceus amurensis (Erinaceidae) and higher phylogeny of the family Erinaceidae
Authors: N.H. Kim, S.J. Lim, H.M. Chae and Y.C. Park
We sequenced and characterized the complete mitogenome (KX964606) of the Amur hedgehog Erinaceus amurensis to provide more data for comparative mitogenomics of the genus Erinaceus (Erinaceidae). The mitogenome of E. amurensis is a circular molecule 16,941 bp long, consisting of a control region and a conserved set of 37 genes .. Read More»
Genet. Mol. Res. 16(1): gmr16019300
DOI: 10.4238/gmr16019300
Extraction of proteins and preliminary characterization of physicochemical properties in Toona sinensis fruit
Authors: W.-Z. Li, W.-N. Han, B. Liu, S.-H. Ding, X.-K. Zhang and R.-S. Wang
We investigated the extraction of Toona sinensis fruit proteins and preliminarily characterized their physicochemical properties. The results showed that optimal extraction occurred under conditions of pH 10.5, a duration of 40 min, a liquid-to-solid ratio of 25:1, and a temperature of 40°C by an orthogonal design using T... Read More»
Genet. Mol. Res. 16(1): gmr16019177
DOI: 10.4238/gmr16019177
Effect of GJB2 235delC and 30-35delG genetic polymorphisms on risk of congenital deafness in a Chinese population
Authors: Y. Xiong, M. Zhong, J. Chen, Y.L. Yan, X.F. Lin and X. Li
Congenital deafness is a serious and irreversible condition in humans. The GJB2 gene is implicated in the pathogenesis of autosomal recessive nonsyndromic hearing loss. Its 235delC and 30-35delG polymorphisms are reported to be associated with risk of hereditary deafness. However, the effect of the interaction between GJB2 235.. Read More»
Genet. Mol. Res. 16(1): gmr16019165
DOI: 10.4238/gmr16019165
Molecular characterization, expression, and functional analysis of chicken TRAF6
Authors: J. Jin, J.S. Ran, C.W. Yang, X.S. Jiang, Y.G. Zhou, Z.Q. Feng, Y. Wang, D. Lan, P. Ren and Y.P. Liu
Tumor necrosis factor receptor-associated factor 6 (TRAF6) is a crucial adaptor molecule of the interleukin-1 receptor/Toll-like receptor (IL-1/TLR) superfamily, which can trigger downstream signaling cascades involved in innate immunity. The function of TRAF6 has been clarified in mammals but is poorly understood in chicken. .. Read More»
Genet. Mol. Res. 16(1): gmr16019138
DOI: 10.4238/gmr16019138
Cloning and expression of class I chitinases in Hami melon after Penicillium infection
Authors: F.Y. Jiang, B.B. Shui, F.X. Tang and C.H. Shan
Chitinases are important disease-related proteins that play critical roles in plant defense against disease. To investigate the function of chitinases in the resistance of Hami melon to Penicillium infection, the gene encoding chitinases, HmCHT-2, was cloned and RT-PCR was used to measure expression levels of HmCHT-2. When the.. Read More»
Genet. Mol. Res. 16(1): gmr16019085
DOI: 10.4238/gmr16019085
Early selection of sugarcane using path analysis
Authors: R.P. Barbosa, F. Alc�¢ntara Neto, L.M. Gravina, G.A. Gravina, M.G.T. Portela and A.A.C. Bezerra
The aim of this study was to analyze sugarcane (Saccharum officinarum) biometric and technological data, obtained at different timepoints, using path analysis. The experiment was conducted in União, PI, Brazil, and evaluated 12 sugarcane genotypes (RB036066, RB9438, RB935744, RB021764, RB021754, RB021534, RB966229, RB97.. Read More»
Genet. Mol. Res. 16(1): gmr16019038
DOI: 10.4238/gmr16019038
Nested polymerase chain reaction technique for the detection of Gpc3 and Afp mRNA in liver cancer micrometastases
Authors: J. Luo, K. Yang and Y.G. Wen
The incidence of liver cancer has gradually risen to a high level in China, and tumor metastasis occurs via multiple pathways. Alpha fetal protein (AFP) is the main biomarker of liver cancer micrometastases. A recent study showed that glypican-3 (GPC3), which is abundant in hepatoma cells, has promising specificity and could b.. Read More»
Genet. Mol. Res. 16(1): gmr16018947
DOI: 10.4238/gmr16018947