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Z.H. Li

Publications of : Z.H. Li
Human Genetics   Research Article

Role of IL17A rs2275913 and rs3748067 polymorphisms in the risk cervical cancer

Cervical cancer is a serious public health problem and is associated with high cancer-related mortality in females worldwide. The expression of IL17A can increase the migration and invasiveness of cervical cancer cells by activating the NF-κB signal pathway. Single-nucleotide polymorphisms (SNPs) can alter gene function and protein expression. We examined the .. Read More»

Genet. Mol. Res. 16(3): gmr16038826

DOI: 10.4238/gmr16038826

Human Genetics   Research Article

Characterization of novel expressed sequence tag-simple sequence repeat markers and analysis of genetic diversity in four geographic populations of Thais luteostoma

    W. Li, H.F. Jiao, Z.H. Lin, Y.B. Bao

In this study, the genetic diversity in four geographic populations (Yushan Island, Zhoushan, Wenzhou, and Xiamen) of Thais luteostoma was analyzed using 21 microsatellite loci. The results of this study showed that the alleles obtained from different populations ranged from 2 to 8. The average number of alleles and effective alleles were 4.59 and 3.16, respectively.. Read More»

Genet. Mol. Res. 15(4): gmr15048702

DOI: 10.4238/gmr15048702

Animal Genetics   Research Article

Transcriptome survey of phototransduction and clock genes in marine bivalves

    X.J. Sun, L.Q. Zhou, J.T. Tian, Z.H. Liu, B. Wu, Y.H. Dong, A.G. Yang and W.M. Ma

Marine animals exhibit a variety of biological rhythms, such as solar and lunar-related cycles; however, our current molecular understanding of biological rhythms in marine animals is quite limited. Identifying and understanding the expression patterns of clock genes from available transcriptomes will help elucidate biological rhythms in marine species. Here, we per.. Read More»

Genet. Mol. Res. 15(4): gmr15048726

DOI: 10.4238/gmr15048726

Human Genetics   Research Article

Effect of continuous infusion of midazolam on immune function in pediatric patients after surgery

    H.B. Lu, Y.P. Jia, Z.H. Liang, R. Zhou and J.Q. Zheng

The current study was performed to investigate the effects of midazolam on immune function in pediatric patients after surgery and possible mechanism involved. Patients who needed sedation for more than 2 consecutive days after undergoing surgery in the Pediatric Surgery Department of our hospital were enrolled for the study. Fifty-six patients (5-14 years old) were randomly divided into midazo.. Read More»

Genet. Mol. Res. 14(3): 2015.August.21.7

DOI: 10.4238/2015.August.21.7

Medical Genetics   Research Article

Clinical features and treatment of endophthalmitis after cataract surgery

    J. Zhu and Z.H. Li

The aim of this study was to investigate the clinical features and treatment results of endophthalmitis after cataract surgery. Five patients with endophthalmitis after phacoemulsification with intraocular lens implantation were enrolled in this study. The pathogenesis, clinical manifestation, and surgical outcomes of 5 patients were compared. Three patients were surgically treated with anterio.. Read More»

Genet. Mol. Res. 14(2): 2015.June.18.4

DOI: 10.4238/2015.June.18.4

Plant Genetics   Research Article

An expression profiling analysis of hybrid millet and its parents at grain filling stage

    Z.H. Liu, H.M. Zhang, G.L. Li, Y.M. Zhang, H.C. Li and X.L. Guo

Heterosis has been widely used in crop breeding and production. However, a shortage of genes known to function in heterosis significantly limits our understanding of the molecular basis underlying heterosis. Here, we report 740 differentially expressed genes (DEGs) in the leaves of the hybrid millet Zhang No.5 and its parents at the grain filling stage determined using Solexa Illumina digital g.. Read More»

Genet. Mol. Res. 14(3): 2015.July.14.8

DOI: 10.4238/2015.July.14.8

Plant Genetics   Research Article

Development and characterization of polymorphic microsatellite markers for Castanopsis hystrix (Fagaceae)

    Y. Jiang, Z.H. Li, J.Y. Zhu and H.L. Liu

Castanopsis hystrix is one of the most important and dominant species in evergreen broad-leaved forests in subtropical China. However, the population of this species undergone severe decline because of deforestation over the past 2 decades. For both conservation and forestry management, it is essential to develop molecular markers for C. hystrix. We identified 11 microsatellite loci in 2 wild p.. Read More»

Genet. Mol. Res. 14(1): http://dx.doi.org/2015.March.30.1

DOI: http://dx.doi.org/10.4238/2015.March.30.1

Bioinformatics   Research Article

Paeonia (Paeoniaceae) expressed sequence tag-derived microsatellite markers transferred to Paeonia delavayi

    D.X. Wang, H. Ma, Y.L. Zhang, A.A. Duan, W.J. Li and Z.H. Li

Paeonia Franchet contains approximately 30 species of perennial herbs and is the only member of the family Paeoniaceae. Paeonia delavayi is an endangered ornamental plant that has a compound flower color and is endemic to southwest China. Its optimal habitats have been fragmented and its population size has greatly decreased as a result of human activities. Using a modified biotin-streptavidin .. Read More»

Genet. Mol. Res. 12(2): 2013.April.17.6

DOI: 10.4238/2013.April.17.6

Microbial Genetics   Research Article

Thirty-four Musa (Musaceae) expressed sequence tag-derived microsatellite markers transferred to Musella lasiocarpa

    W.J. Li, H. Ma, Z.H. Li, Y.M. Wan, X.X. Liu and C.L. Zhou

We assembled 31,308 publicly available Musa EST sequences into 21,129 unigenes; 4944 of them contained 5416 SSR motifs. In all, 238 unigenes flanking SSRs were randomly selected for primer design and then tested for amplification in Musella lasiocarpa. Seventy-eight primer pairs were found to be transferable to this species, and 49 displayed polymorphism. A set of 34 polymorphic SSR markers was.. Read More»

Genet. Mol. Res. 11(3): 2012.August.6.13

DOI: 10.4238/2012.August.6.13

Human Genetics   Research Article

Functional polymorphisms of the cyclooxygenase-2 gene and prognosis of hepatocellular carcinoma - a cohort study in Chinese people

    R. Liang, X.X. Yan, Y. Lin, Q. Li, C.L. Yuan, Z.H. Liu and Y.Q. Li

Cyclooxygenase-2 (COX-2) influences carcinogenesis through regulation of angiogenesis, apoptosis, cytokine expression, and immune response suppression. It has been well established that COX-2 is overexpressed in a variety of human cancers, such as hepatocellular carcinoma (HCC). In this study, we aimed to evaluate the association between COX-2 polymorphisms and prog.. Read More»

Genet. Mol. Res. 15(2): gmr.15028093

DOI: 10.4238/gmr.15028093