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Y.K. Zhou

Publications of : Y.K. Zhou
Human Genetics   Research Article

Mechanism of reversal of multidrug resistance by curcumin in human colorectal cancer cell line HCT-8/5-FU

Since there are no studies on the reversal of multidrug resistance by curcumin in the human colorectal cancer cell line HCT-8/5-FU, our aim was to search for highly efficient reversal agents and investigate the underlying mechanisms of this reversal. The cytotoxic effects of curcumin and 5-FU on HCT-8 and HCT-8/5-FU cells and the reversal effects of 5-FU in combinat.. Read More»

Genet. Mol. Res. 16(2): gmr16029414

DOI: 10.4238/gmr16029414

Animal Genetics   Research Article

Cloning and sequence analysis of the coding sequence of β-actin cDNA from the Chinese alligator and suitable internal reference primers from the β-actin gene

    H.N. Zhu, S.Z. Zhang, Y.K. Zhou, C.L. Wang and X.B. Wu

β-Actin is an essential component of the cytoskeleton and is stably expressed in various tissues of animals, thus, it is commonly used as an internal reference for gene expression studies. In this study, a 1731-bp fragment of β-actin cDNA from Alligator sinensis was obtained using the homology cloning technique. Sequence analysis showed that this fragment .. Read More»

Genet. Mol. Res. 14(4): 2015.October.9.4

DOI: 10.4238/2015.October.9.4