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M.S.F. Tsuboy

Publications of : M.S.F. Tsuboy
Human Genetics   Research Article

First cytotoxic, genotoxic, and antigenotoxic assessment of Euterpe oleracea fruit oil (açaí) in cultured human cells

Euterpe oleracea Mart., popularly known as “açaí”, is a tropical fruit from the Amazon region where it has considerable economic importance. Açaí has been used as food and for several medicinal purposes. Despite the widespread use of this fruit, there is a lack of data regarding the safety of using this fruit oil exclusively. .. Read More»

Genet. Mol. Res. 16(3): gmr16039700

DOI: 10.4238/gmr16039700

Cytogenomics   Research Article

Genotoxic evaluation of the antimalarial drugs artemisinin and artesunate in human HepG2 cells and effects on CASP3 and SOD1 gene expressions

    I. Aquino, M.S.F. Tsuboy, J.C. Marcarini, M.S. Mantovani, F.F. Perazzo and E.L. Maistro

The malaria treatment recommended by the World Health Organization involves medicines derived from artemisinin, an active compound extracted from the plant Artemisia annua, and some of its derivatives, such as artesunate. Considering the lack of data regarding the genotoxic effects of these compounds in human cells, the objective of this study was to evaluate the cytotoxicity and genotoxicity, .. Read More»

Genet. Mol. Res. 12(3): 2013.July.24.6

DOI: 10.4238/2013.July.24.6