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J.C.T. Carvalho

Publications of : J.C.T. Carvalho
Human Genetics   Research Article

First cytotoxic, genotoxic, and antigenotoxic assessment of Euterpe oleracea fruit oil (açaí) in cultured human cells

Euterpe oleracea Mart., popularly known as “açaí”, is a tropical fruit from the Amazon region where it has considerable economic importance. Açaí has been used as food and for several medicinal purposes. Despite the widespread use of this fruit, there is a lack of data regarding the safety of using this fruit oil exclusively. .. Read More»

Genet. Mol. Res. 16(3): gmr16039700

DOI: 10.4238/gmr16039700

Medical Genetics   Research Article

In vitro study of the cytotoxic and genotoxic effects of indomethacin-loaded Eudragit® L 100 nanocapsules

    J.G. Froder, D. Dupeyrón, J.C.T. Carvalho and E.L. Maistro

Indomethacin is a non-steroidal anti-inflammatory agent included in one of the most commonly used drug classes worldwide. The use of this drug results in certain side effects, including gastrointestinal complications. Therefore, there exists a need to develop better methods for the delivery of such drugs into the body, such as those employing nanoparticles. The aim of the present study was to e.. Read More»

Genet. Mol. Res. 15(3): gmr.15038727

DOI: 10.4238/gmr.15038727