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Publications of : Kavitha Sankaranarayanan
Medical Genetics   Research Article

Expression of HCN and sodium channels in murine model of Type I diabetes

Pancreatic apoptosis is an important event in the pathogenesis of Type 1 Diabetes. It is characterized by secretion and binding of inflammatory cytokines to the pancreatic islets, that activate downstream signaling mechanism. These signaling mechanisms finally increase intracellular calcium level and that lead to the activation of apoptotic pathways. Ion channels are transmembrane protein, resp.. Read More»

Genet. Mol. Res. 18(2):

Human Genetics   Research Article

Electroporation induced membrane permeability changes at the ionic level

Background/Aim: Electrochemotherapy is an innovative method for the localized treatment of cutaneous and subcutaneous metastatic cancers. The aim of the study is to assess the changes at the plasma membrane and its recovery time by monitoring the regulated passage of ions through specific ion channels as measured by electrophysiology. Materials and Methods: Electroporation and patch cla.. Read More»

Genet. Mol. Res. 18(3):

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