Arezou Sayad

Investigation of the role of apoptosis, necroptosis and DNA damage signaling pathways in multiple sclerosis

• Romina Dastmalchi
• Arezou Sayad
• Mir Davood Omrani
• Soudeh Ghafouri-Fard
• Shahram Arsang-Jang
• Mehrdokht Mazdeh
• Mohammad Taheri

Multiple sclerosis (MS) as the most common autoimmune disorder in the central nervous system is a major health problem. MS is a complex disease with multiple environmental and genetic factors participating in it. In the present study, we evaluated the expression of 3 genes named BCL2, CASP2 and CASP8 in peripheral blood of 50 MS patients and 50 healthy controls to investigate the role of apopto.. Read More»

Genet. Mol. Res. 17(4): http://dx.doi.org/gmr16039937

DOI: http://dx.doi.org/10.4238/gmr16039937

NNT and NNT-AS1 expression levels are not different between bipolar patients and healthy subjects

• Soudeh Ghafouri-Fard
• Mohammad Taheri
• Vahid Kholghi Oskooie
• Mir Davood Omrani
• Arezou Sayad

Nicotinamide nucleotide transhydrogenase (NNT) participates in redox and energy interconnections. Nnt silencing in N27 dopaminergic cells has changed basal, extra, and greatest mitochondrial oxygen absorption rates and made these cell vulnerable to constant upsurges in H2O2. NNT-antisense RNA1 (NNT-AS1) is transcribed from the opposite stand of NNT gene and is possibly involved in regulation of.. Read More»

Genet. Mol. Res. 18(1):