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Paper Highlights

Research Article   February 3, 2020
Genet. Mol. Res.: 19(1): 1-10.

Uncoupling Proteins and Cardiac Apoptosis in High Fat Diet-Fed Male Rats

This study aimed to assess impact of high fat diet (HFD) on cardiac apoptosis, and cardiac uncoupling proteins (UCPs) 2&3 expression. Twenty rats were fed either (45%) or (10%) fat diet for 6 months, then cardiac tissue expression of BAX, Bcl2, Fas, Fas-L (markers for apoptotic pathways) and UCP 2&3 were assessed. Results revealed enhancement of intrinsic and extrinsic cardiomyocyte apo.. Read More»

Research Article   September 5, 2019
Genet. Mol. Res.: 18(3): 1-14.

Electroporation induced membrane permeability changes at the ionic level

Background/Aim: Electrochemotherapy is an innovative method for the localized treatment of cutaneous and subcutaneous metastatic cancers. The aim of the study is to assess the changes at the plasma membrane and its recovery time by monitoring the regulated passage of ions through specific ion channels as measured by electrophysiology. Materials and Methods: Electroporation and patch cla.. Read More»

Research Article   July 5, 2019
Genet. Mol. Res.: 18(2): 1-10.

Differential expression of genes associated with low-level vancomycin resistance in Staphylococcus aureus

Heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) and vancomycin-intermediate S. aureus (VISA) have been associated with treatment failure, and hVISA cannot be detected by routine disc diffusion test. Currently, there is no specific genetic marker for detection of these strains. The aim of the current study was to investigate the differential expression of si.. Read More»

Research Article   May 5, 2019
Genet. Mol. Res.: 18(2): 1-9.

Development and characterization of microsatellite molecular markers for the eye mask frog Batrachyla taeniata (Girard, 1855)

Batrachyla taeniata (Batrachylidae) is a small frog from Chile and Argentina with a distributional range that spans more than 1500 km. However, their populations are threatened due to the change in land use, deforestation, and human settlements. Through massive sequencing runs in ION Torrent PGM, was built DNA fragment library, from which we finally isolated and characterized 25 micros.. Read More»

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