Microbial Genetics
Effect of bone marrow mesenchymal stem cells on the TGF-�²1/Smad signaling pathway of hepatic stellate
Authors: X.E. Sun, X.Q. Zhang and M.M. Liu
This study investigated the effect of bone marrow mesenchymal stem cells (BMCs) on the transforming growth factor-β1 (TGF-b1)-induced activation of the Smad signaling pathway in rat hepatic stellate cells (HSCs). There were four experimental groups: 1) a blank control group, 2) a TGF-b1 treatment group, 3) an MSC-combined group, and 4) an induced MSC.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.31.23
- DOI:
- 10.4238/2015.July.31.23
A cytological study of anther and pollen development in Camellia oleifera
Authors: C. Gao, D.Y. Yuan, B.F. Wang, Y. Yang, D.M. Liu and Z.Q. Han
The plant species Camellia oleifera is an important producer of edible oil in China. However, it suffers from a low fruit-setting rate. This study used high resolution scanning electron microscopy of semi-thin tissue sections to investigate anther development and pollen formation, and to determine whether problems in forming functional pollen cause low se.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.31.24
- DOI:
- 10.4238/2015.July.31.24
Associations between tumor necrosis factor-�± polymorphisms and susceptibility to pulmonary tuberculosis: meta-analysis
Authors: Y.H. Lee and G.G. Song
The aim of this study was to determine whether tumor necrosis factor-α (TNF-α) polymorphisms are associated with susceptibility to pulmonary tuberculosis (PTB) in different ethnic populations. MEDLINE and Embase databases and manual searches were employed to identify articles in which TNF-α polymorphisms were determined in patients with .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.31.8
- DOI:
- 10.4238/2015.July.31.8
Mn-SOD 47 CC genotype in combination with high tea consumption may prevent complications in Tunisian type-2 diabetes
Authors: H. Abaidi, S. Denden, A. Ghazouani, A. Trim�¨che, C. Snoussi, A. Haj Khelil, J. Ben Chibani and M.H. Hamdaoui
Reactive oxygen species metabolizing enzymes may play an important role in the prevention of type-2 diabetes (T2D) complications. We analyzed the association between Cu/Zn-SOD +35 A/C, Mn-SOD T47C, and CAT -21 A/T gene polymorphisms and complications, in combination with tea consumption in Tunisian T2D. A sample of 366 T2D subjects was enrolled in this st.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.31.9
- DOI:
- 10.4238/2015.July.31.9
Association of TLR2 and TLR4 non-missense single nucleotide polymorphisms with type 2 diabetes risk in a southern Chinese population: a case-control study
Authors: W.H. Huang, L.H. Nie, L.J. Zhang, L.P. Jing, F. Dong, M. Wang, N. Zhang, Y. Liu, B.H. Zhang, C. Chen, H.S. Lin, X.C. Wei, G. Yang and C.X. Jing
Toll-like receptors (TLRs), the triggers of the innate and adaptive immune responses, are involved in the pathogenesis of type 2 diabetes mellitus (T2DM). Several studies have investigated the effects of genetic polymorphisms in TLR4 and TLR2, but they have yielded limited results. We investigated whether non-missense geneticpolymorphisms in the regulator.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.31.18
- DOI:
- 10.4238/2015.July.31.18
Correlation between the decrease of cholesterol efflux from macrophages in patients with type II diabetes mellitus and down-regulated CYP7A1 expression
Authors: L.D. Bao, C.Q. Li, R. Peng, X.H. Ren, R.L. Ma, Y. Wang and H.J. Lv
The purpose of this study was to examine the changes of cellular cholesterol efflux from macrophages in patients with type II diabetes mellitus (DM), and to determine the expression of CYP7A1, ABCG5, and LXRβ therein. We recruited 30 patients with type II DM (including 15 patients complicated with coronary heart disease and 15 patients with DM only) .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.31.20
- DOI:
- 10.4238/2015.July.31.20
Consistency between molecular phylogeny and morphological classification of the Salix matsudana Koidz. complex (Salicaceae)
Authors: S.H. Du, Z.S. Wang, Y.X. Li, D.S. Wang and J.G. Zhang
The morphological species concept is based on morphological traits, which are often subject to subjectivity or artifact. Molecular evidence is needed to test the reliability of morphological classification of taxa that are controversial and to provide appropriate taxonomic delimitation. In this study, we used 15 single-copy nuclear loci and 2 chloroplast .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.31.15
- DOI:
- 10.4238/2015.July.31.15
Cloning and expression of the porcine attaching and effacing-associated (paa) gene of enteropathogenic Escherichia coli
Authors: D.A. Pereira, E.C. Teixeira Florian, M.A. Ono, C. Nachi Rossi, O. Vidotto and M.C. Vidotto
Porcine enteropathogenic Escherichia coli (PEPEC) produce an outer membrane protein (intimin) called Paa (porcine attaching and effacing-associated), which is involved in the pathogenesis of E. coli in piglets with diarrhea. The paa gene of a PEPEC strain isolated in Paraná, Brazil, was amplified by polymerase chain reaction, sequenced, and cloned .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.31.5
- DOI:
- 10.4238/2015.July.31.5
Related factors and prevalence of Parkinson�s disease among Uygur residents in Hetian, Xinjiang Uygur Autonomous Region
Authors: X.L. Yang, Q. Luo, H.X. Song, Y.L. Wang, Y.N. Yao and H. Xia
The aim of this study was to identify the factors related to and determine the prevalence of ParkinsonâÃ?Â?Ã?Â?s disease (PD) among Uygur residents in Hetian Prefecture, Xinjiang Uygur Autonomous Region. This population-based prospective cohort study used structured questionnaires to screen for factors related to PD. The prevalence in different age .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.July.31.1
- DOI:
- 10.4238/2015.July.31.1
A cultured endophyte community is associated with the plant Clerodendrum inerme and antifungal activity
Authors: B. Gong, X.H. Yao, Y.Q. Zhang, H.Y. Fang, T.C. Pang and Q.L. Dong
. Fungal endophytes live in the inner tissues of Clerodendrum inerme and may be significant resources for new chemicals in drug discovery. A total of 242 endophytic fungi were recovered from 602 sample segments of C. inerme; 66 were purified. The 66 fungi belonging to 16 taxa and 11 genera (Alternaria, Nigrospora, Bartalinia, Pestalotiopsis, Fusarium, Myc.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.8.6
- DOI:
- 10.4238/2015.June.8.6