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Human Genetics

Human Genetics   Editorials

RETRACTION of articles with plagiarism in common with other publications

Authors: Peng ZA, Lu RB, Xiao DM and Xiao ZM

Genet. Mol. Res. 15(3):
gmr.1503007
DOI:
10.4238/gmr.1503007
Human Genetics   Research Article

Analysis of CD38 and ZAP70 mRNA expression among cytogenetic subgroups of Iranian chronic-lymphocytic-leukemia patients

Authors: H. Teimori, M.T. Akbari, M. Hamid, M. Forouzandeh and E. Bibordi

Chromosomal abnormalities and ZAP70 expression profile are two major independent prognostic markers in B-cell chronic lymphocytic leukemia. We investigated a possible correlation between these two markers. ZAP70 expression using real-time RT-PCR was examined in 20 B-cell chronic lymphocytic leukemia patients with del13q14, 13 .. Read More»

Genet. Mol. Res. 10(4):
2011.October.7.3
DOI:
10.4238/2011.October.7.3
Human Genetics   Research Article

Genetic diversity of HLA-DRB1 alleles in the Tujia population of Wufeng, Hubei Province, China

Authors: X.P. Qiu, L. Zhang, F.Y. Zeng, Y. Wen, C. Li, L.X. Qiu, D.X. Cheng and X.X. Wu

We established a genetic database by investigating human leukocyte antigen (HLA)-DRB1 allelic frequencies in a disease-association study in the Tujia population in Wufang, Hubei, China. The allele frequencies of the HLA-DRB1 locus in 262 healthy, unrelated Tujia individuals living in the Wufeng region of the Hubei Province wer.. Read More»

Genet. Mol. Res. 13(3):
2014.July.2.5
DOI:
10.4238/2014.July.2.5
Human Genetics   Research Article

Molecular characterization of Anthurium genotypes by using DNA fingerprinting and SPAR markers

Authors: J.D. Souza Neto, T.C.B. Soares, L.B. Motta, P.D.S. Cabral and J.A. Silva

We characterized single primer amplification reaction (SPAR) molecular markers from 20 genotypes of Anthurium andraeanum Lind., including 3 from commercial varieties and 17 from 2 communities in the State of Espírito Santo, Brazil. Twenty-four SPAR, consisting of 7 random amplified polymorphic DNA and 17 inter-.. Read More»

Genet. Mol. Res. 13(3):
2014.July.2.6
DOI:
10.4238/2014.July.2.6
Human Genetics   Research Article

Two novel NPHS1 mutations in a Chinese family with congenital nephrotic syndrome

Authors: L.Q. Wu, J.J. Hu, J.J. Xue and D.S. Liang

Congenital nephrotic syndrome of the Finnish type (CNF) is a lethal, autosomal recessive disorder mainly caused by mutations in the NPHS1 gene; it is found at a relatively high frequency in Finns. We investigated the disease-causing mutations in a Chinese family with CNF and developed a prenatal genetic diagnosis for their lat.. Read More»

Genet. Mol. Res. 10(4):
2011.October.18.1
DOI:
10.4238/2011.October.18.1
Human Genetics   Research Article

HLA-B51 subtypes in Turkish patients with Beh�§etâ��s disease and their correlation with clinical manifestations

Authors: D.D. Demirseren, G.G. Ceylan, G. Akoglu, S. Emre, S. Erten, A. Arman and A. Metin

Behçet’s disease (BD) is a multisystemic inflammatory disease believed to be triggered by microbial or environmental factors on a genetic platform. Clinically, it may have an impact on many body systems, including the mucocutaneous, ocular, articular, vascular, and neurological systems. In this study, we aimed to .. Read More»

Genet. Mol. Res. 13(3):
2014.July.2.8
DOI:
10.4238/2014.July.2.8
Human Genetics   Research Article

FAS -670A>G promoter polymorphism is associated with soluble Fas levels in primary Sj�¶grenâ��s syndrome

Authors: B.A. Trevi�±o-Talavera, C.A. Palafox-S�¡nchez, J.F. Mu�±oz-Valle, G. Orozco-Barocio, R.E. Navarro-Hern�¡ndez, M. V�¡zquez-Del Mercado, I. Garc�­a de la Torre and E. Oregon-Romero

Primary Sjögren’s syndrome (pSS) is a chronic systemic autoimmune disease characterized by lymphocytic infiltration of exocrine glands. Soluble Fas receptor (sFas) has been suggested as a Fas-mediated apoptosis blocker that could impair clonal deletion in infiltrated autoreactive cells. The FAS -670A>G promoter p.. Read More»

Genet. Mol. Res. 13(3):
2014.July.2.12
DOI:
10.4238/2014.July.2.12
Human Genetics   Research Article

Antibody preparation and identification of the Cashmere goat c-kit protein in the testes

Authors: S.C.L. Wu, F.H. Luo*, Q.F. Kong and Y.J. Wu

The c-kit protein plays a major role in the regulation of germ cell development. Its expression and distribution in rodent testes have been widely reported. However, research regarding c-kit expression in domestic animals is scarce, and the expression pattern and distribution of c-kit in germ cells have not been clearly define.. Read More»

Genet. Mol. Res. 13(3):
2014.July.2.13
DOI:
10.4238/2014.July.2.13
Human Genetics   Research Article

Interleukin-6 -572G/C polymorphism and prostate cancer susceptibility

Authors: W.J. Huan, L.J. Wu, Z.C. Min, L.T. Xu, C.M. Guo, Z.P. Chen, X.J. Lou, B. Xu3and B.D. Lv

Strong evidence suggests that cancer-associated inflammation promotes tumor growth and progression, and interleukin-6 (IL6) is an important modulator of inflammation. However, the roles of IL6 and mutations of its corresponding gene in prostate cancer have not been clearly documented. We retrieved data from the Oncomine database concerning IL6 expression .. Read More»

Genet. Mol. Res. 15(3):
gmr.15037563
DOI:
10.4238/gmr.15037563
Human Genetics   Research Article

Correlation between polymorphisms in the estrogen receptor �± gene and coronary heart disease: A meta-analysis

Authors: W. Zhou, K.H. He and M.H. Chen

The aim of this study was to conduct a systematic evaluation the correlation between polymorphisms in the estrogen receptor α gene (ESRα) and coronary heart disease susceptibility. Case-control studies until August 2015 analyzing the correlation between the ESRα PvuII T/C polymorphism and coronary heart disease were obtained from various.. Read More»

Genet. Mol. Res. 15(3):
gmr.15037835
DOI:
10.4238/gmr.15037835