
Authors: Peng ZA, Lu RB, Xiao DM and Xiao ZM
Authors: H. Teimori, M.T. Akbari, M. Hamid, M. Forouzandeh and E. Bibordi
Chromosomal abnormalities and ZAP70 expression profile are two major independent prognostic markers in B-cell chronic lymphocytic leukemia. We investigated a possible correlation between these two markers. ZAP70 expression using real-time RT-PCR was examined in 20 B-cell chronic lymphocytic leukemia patients with del13q14, 13 .. Read More»
Authors: X.P. Qiu, L. Zhang, F.Y. Zeng, Y. Wen, C. Li, L.X. Qiu, D.X. Cheng and X.X. Wu
We established a genetic database by investigating human leukocyte antigen (HLA)-DRB1 allelic frequencies in a disease-association study in the Tujia population in Wufang, Hubei, China. The allele frequencies of the HLA-DRB1 locus in 262 healthy, unrelated Tujia individuals living in the Wufeng region of the Hubei Province wer.. Read More»
Authors: J.D. Souza Neto, T.C.B. Soares, L.B. Motta, P.D.S. Cabral and J.A. Silva
We characterized single primer amplification reaction (SPAR) molecular markers from 20 genotypes of Anthurium andraeanum Lind., including 3 from commercial varieties and 17 from 2 communities in the State of Espírito Santo, Brazil. Twenty-four SPAR, consisting of 7 random amplified polymorphic DNA and 17 inter-.. Read More»
Authors: L.Q. Wu, J.J. Hu, J.J. Xue and D.S. Liang
Congenital nephrotic syndrome of the Finnish type (CNF) is a lethal, autosomal recessive disorder mainly caused by mutations in the NPHS1 gene; it is found at a relatively high frequency in Finns. We investigated the disease-causing mutations in a Chinese family with CNF and developed a prenatal genetic diagnosis for their lat.. Read More»
Authors: D.D. Demirseren, G.G. Ceylan, G. Akoglu, S. Emre, S. Erten, A. Arman and A. Metin
Behçet’s disease (BD) is a multisystemic inflammatory disease believed to be triggered by microbial or environmental factors on a genetic platform. Clinically, it may have an impact on many body systems, including the mucocutaneous, ocular, articular, vascular, and neurological systems. In this study, we aimed to .. Read More»
Authors: B.A. TreviÃ?±o-Talavera, C.A. Palafox-SÃ?¡nchez, J.F. MuÃ?±oz-Valle, G. Orozco-Barocio, R.E. Navarro-HernÃ?¡ndez, M. VÃ?¡zquez-Del Mercado, I. GarcÃ?Âa de la Torre and E. Oregon-Romero
Primary Sjögren’s syndrome (pSS) is a chronic systemic autoimmune disease characterized by lymphocytic infiltration of exocrine glands. Soluble Fas receptor (sFas) has been suggested as a Fas-mediated apoptosis blocker that could impair clonal deletion in infiltrated autoreactive cells. The FAS -670A>G promoter p.. Read More»
Authors: S.C.L. Wu, F.H. Luo*, Q.F. Kong and Y.J. Wu
The c-kit protein plays a major role in the regulation of germ cell development. Its expression and distribution in rodent testes have been widely reported. However, research regarding c-kit expression in domestic animals is scarce, and the expression pattern and distribution of c-kit in germ cells have not been clearly define.. Read More»
Authors: W.J. Huan, L.J. Wu, Z.C. Min, L.T. Xu, C.M. Guo, Z.P. Chen, X.J. Lou, B. Xu3and B.D. Lv
Strong evidence suggests that cancer-associated inflammation promotes tumor growth and progression, and interleukin-6 (IL6) is an important modulator of inflammation. However, the roles of IL6 and mutations of its corresponding gene in prostate cancer have not been clearly documented. We retrieved data from the Oncomine database concerning IL6 expression .. Read More»
Authors: W. Zhou, K.H. He and M.H. Chen
The aim of this study was to conduct a systematic evaluation the correlation between polymorphisms in the estrogen receptor α gene (ESRα) and coronary heart disease susceptibility. Case-control studies until August 2015 analyzing the correlation between the ESRα PvuII T/C polymorphism and coronary heart disease were obtained from various.. Read More»