Human Genetics
Next-generation sequencing analysis of the ARMS2 gene in Turkish exudative age-related macular degeneration patients
Authors: H. Bardak, M. Gunay, Y. Ercalik, Y. Bardak, H. Ozbas and O. Bagci
Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries. It is a complex disease with both genetic and environmental risk factors. To improve clinical management of this condition, it is important to develop risk assessment and prevention strategies for environmental influences, and esta.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019135
- DOI:
- 10.4238/gmr16019135
An experimental study on the use of icariin for improving thickness of thin endometrium
Authors: A.W. Le, Z.H. Wang, X.Y. Dai, T.H. Xiao, R. Zhuo, B.Z. Zhang, Z.L. Xiao and X.J. Fang
This study aimed to investigate the effect of icariin (ICA) on thin endometrium in a rat model. To this end, 6- to 8-week-old female Sprague Dawley rats (105) were randomly divided into 7 groups: untreated, vehicle-treated (lavage with NaCl), high-dose ICA (lavage with ICA at 200 mgâÂ?Â?kg-1âÂ?Â?day-1), medium-dose ICA (lava.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019126
- DOI:
- 10.4238/gmr16019126
An assessment of the correlation between early postinfarction pyramidal tract Wallerian degeneration and nerve function recovery using diffusion tensor imaging
Authors: A.H. Guo, F.L. Hao, L.F. Liu, B.J. Wang and X.F. Jiang
This study aimed to evaluate the clinical significance of diffusion tensor imaging (DTI) in the early diagnosis of pyramidal tract Wallerian degeneration (WD) and assessment of neurological recovery following cerebral infarction. This study included 23 patients with acute cerebral infarction and 10 healthy adult controls. All .. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019035
- DOI:
- 10.4238/gmr16019035
Expression of prion protein in the cerebrospinal fluid of patients with Parkinson�s disease complicated with rapid eye movement sleep behavior disorder
Authors: W.J. Zhang, X.L. Shang, J. Peng, M.H. Zhou and W.J. Sun
Parkinson’s disease (PD) is one of the most common neurodegenerative diseases and mainly manifests with decreasing numbers of dopaminergic neurons. Rapid eye movement (REM) sleep behavior disorder (RBD) has an incidence of 15-47% in all PD patients. Prion proteins (PrPs), which are expressed in both neurons and glial cel.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019022
- DOI:
- 10.4238/gmr16019022
Potential use of molecular markers for prediction of genotypic values in hybrid maize performance
Authors: M. Balestre, R.G. Von Pinho, J.C. Souza and R.L. Oliveira
We evaluated the potential of genetic distances estimated by microsatellite markers for the prediction of the performance of single-cross maize hybrids. We also examined the potential of molecular markers for the prediction of genotypic values and the applicability of the Monte Carlo method for a correlation of genetic distanc.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr644
- DOI:
- 10.4238/vol8-4gmr644
Characterization of the resistance gradient of cacao genotypes (F2 Sca6 x ICS1) to black pod disease using phytopathometric, genetic and molecular approaches
Authors: E.S.L. Santos
-.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4ta023
- DOI:
- 10.4238/vol8-4ta023
Mitochondrial DNA insertions in the nuclear Capra hircus genome
Authors: F.Y. Ning, J. Fu and Z.H. Du
Nuclear mitochondrial pseudogenes (numts), originating from mtDNA insertions into the nuclear genome, have been detected in many species. However, the distribution of numts in the newly published nuclear genome of domestic goat (Capra hircus) has not yet been explored. We used the entire goat mtDNA sequence and nuclear genome,.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16018266
- DOI:
- 10.4238/gmr16018266
Biometric, genetic and molecular evaluations targeting conservation and improvement of Passiflora spp
Authors: C.B.M. Cerqueira-Silva
-.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4ta024
- DOI:
- 10.4238/vol8-4ta024
Genotypic stability and adaptability in tropical maize based on AMMI and GGE biplot analysis
Authors: M. Balestre, R.G. Von Pinho, J.C. Souza and R.L. Oliveira
We evaluated the phenotypic and genotypic stability and adaptability of hybrids using the additive main effect and multiplicative interaction (AMMI) and genotype x genotype-environment interaction (GGE) biplot models. Starting with 10 single-cross hybrids, a complete diallel was done, resulting in 45 double-cross hybrids that .. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr658
- DOI:
- 10.4238/vol8-4gmr658
Cytogenetic and molecular analysis of an apomictic cassava hybrid and its progeny
Authors: N.M.A. Nassar, P.T.C. Gomes, A.M. Chaib1, N.N. Bomfim,R.C.D. Batista and R.G. Collevatti
An interspecific hybrid between cassava and Manihot glaziovii acquired an apomixis gene from the parent M. glaziovii. This hybrid was exposed to open pollination during three subsequent generations. Seven sibs and the maternal progenitor of the fourth generation were genotyped using six microsatellite loci previously developed.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr674
- DOI:
- 10.4238/vol8-4gmr674