Human Genetics
Comparative genetic variability between broodstock and offspring populations of Korean starry flounder used for stock enhancement in a hatchery by using microsatellite DNA analyses
Authors: H.S. An, E.-H. Shin, J.W. Lee, M.M. Nam, J.I. Myeong and C.M. An
Korean starry flounder, Platichthys stellatus (Pleuronectidae), is one of the most economically important fishery resources in Korea. We investigated the effect of current artificial reproduction in a hatchery facility, genetic divergence between the broodstock and their offspring populations of starry flounder in a hatchery strain to be stocked into natu.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.4.19
- DOI:
- 10.4238/2013.December.4.19
Insulin-like growth factor binding protein-3 (IGFBP-3) genetic variant and the risk of esophageal squamous cell carcinoma in a Chinese population
Authors: H.-P. Yang, J.-F. Liu, J. Rao, X.-M. Zhang, H.-L. Qian, X.-Q. Niu and Z.-L. Zhao
Insulin-like growth factor binding protein-3 (IGFBP-3) exerts anti-proliferative or pro-apoptotic effects through IGF-dependent as well as IGF-independent mechanisms in vitro. The purpose of this study was to examine the association between genetic variants in IGFBP-3 (rs2270628) and the risk of esophageal squamous cell carcin.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.30.10
- DOI:
- http://dx.doi.org/10.4238/2014.May.30.10
Effect of MPO/H2O2/NO- system on nitric oxide-mediated modification of TTR amyloid and serum TTR in FAP ATTR Val30Met patients
Authors: J.P. Liu, Q.Y. Wang, F. Zheng, J.H. Lu, P. Ge, Y.J. Gu and X.G. Sun
Amyloid deposits consist of protein fibrils and amorphous material, and this deposition is related to oxidative stress. Previously, we demonstrated the presence of high-density lipoproteins and/or lipids in amyloid deposits of familial amyloid polyneuropathy patients. In this study, the presence of myeloperoxidase (MPO) in amy.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.3.9
- DOI:
- 10.4238/2014.April.3.9
Pre-treatment with glutamine reduces genetic damage due to cancer treatment with cisplatin
Authors: R.J. Oliveira, E.S. Sassaki, A.C.D. Monreal, M.T.F.D. Monreal,J.R. Pesarini, M.O. Mauro, R. Matuo, A.F. Silva, N.N. Zobiole,J.M. Siqueira, L.R. Ribeiro, M.S. Mantovani
Cisplatin is an effective antineoplastic drug. However, it provokes considerable collateral effects, including genotoxic and clastogenic activity. It has been reported that a diet rich in glutamine can help inhibit such collateral effects. We evaluated this activity in 40 Swiss mice, distributed into eight experimental groups:.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.2.2
- DOI:
- 10.4238/2013.December.2.2
Analysis of differentially expressed genes in various stages of Duchenne muscular dystrophy by using a network view
Authors: D. Wang, Z.J. Wang, X.X. Song, L.H. Pu, X. Li and Y. Wang
Duchenne muscular dystrophy (DMD), which is caused by mutations in the X-linked dystrophin gene, is a severe and progressive neuromuscular disease with no available cure. By integrating 2 microarray datasets from the Gene Expression Omnibus, we identified differentially expressed genes in 2 stages of DMD and systematically explored their potential disease.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.10.13
- DOI:
- 10.4238/2013.October.10.13
Effects of atorvastatin in combination with ezetimibe on carotid atherosclerosis in elderly patients with hypercholesterolemia
Authors: P. Luo, L. Li, L.X. Wang, H.H. Zhu, S. Du, S.L. Wu, Y.G. Han and G.G. Wang
The aim of this study was to observe the effects of atorvastatin combined with ezetimibe on carotid atherosclerosis in elderly patients with hypercholesterolemia. A total of 84 elderly hypercholesterolemic patients complicated with carotid atherosclerosis were divided into control group (atorvastatin alone) and combined group .. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.3.10
- DOI:
- 10.4238/2014.April.3.10
HMGB3 characterization in gastric cancer
Authors: Y. Gong, Y. Cao, L. Song, J. Zhou, C. Wang, B. Wu
Gastric cancer is a major health problem worldwide; it is the second most common cause of cancer death in the world. Recent studies indicate that the high-mobility group (HMG) of chromosomal proteins is associated with cancer progression. However, HMGB3 has been little studied. We analyzed the co-expression network between HMG.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.2.1
- DOI:
- 10.4238/2013.December.2.1
Epidemiological analysis of dyslipidemia in adults of three ethnicities in Xinjiang, China
Authors: S.X. Guo, R.L. Ma, H. Guo, Y.S. Ding, J.M. Liu, M. Zhang, J.Y. Zhang, S.Z. Xu, S.G. Li, D.S. Rui, Q. Niu and Y.P. Li
This study investigated the prevalence and distribution of dyslipidemia in adults of Uygur, Kazak, and Han ethnicity in Xinjiang, China. A questionnaire including general data, physical examination (blood pressure, body height, and body weight) and blood lipid [total cholesterol (TC), triglyceride (TG), low-density lipoprotein.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.3.11
- DOI:
- 10.4238/2014.April.3.11
Relationship between serum creatinine and obesity in children in Xinjiang, China
Authors: X.-M. Li, Y.-T. Ma, X. Xie, Y.-N. Yang, X.-M. Li and Y.-Y. Zheng
This study was designed to analyze the relationship between serum creatinine and body mass index in children in Xinjiang, China. We used a stratified sampling method to select 5222 children aged 6-17 years in 3 areas in Xinjiang and then measured serum creatinine with an enzymatic method. Our analysis showed that the mean seru.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.3.13
- DOI:
- 10.4238/2014.April.3.13
Value of dual-source computed tomography in evaluating left ventricular function in patients with coronary heart disease
Authors: B.X. Shen, D.H. Peng, Y.G. Li, Y. Liu and Y. Gao
We aimed to assess parameters reflecting left ventricular function by dual-source computed tomography (DSCT) with echocardiography (ECG) as control. Fifty-eight patients with coronary heart disease (CHD) were recruited from January to June 2011; 29 CHD patients had type II diabetes. All patients were assessed by cardiac DSCT and ECG examination. DSCT and .. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.3.14
- DOI:
- 10.4238/2014.April.3.14