Human Genetics
Treatment of vertebral body compression fractures using percutaneous kyphoplasty guided by a combination of computed tomography and C-arm fluoroscopy with finger-touch guidance to determine the needle entry point
Authors: G.Y. Wang, C.C. Zhang, K. Ren, P.P. Zhang, C.H. Liu, Z.A. Zheng, Y. Chen and R. Fang
This study aimed to evaluate the results and complications of image-guided percutaneous kyphoplasty (PKP) using computed tomography (CT) and C-arm fluoroscopy, with finger-touch guidance to determine the needle entry point. Of the 86 patients (106 PKP) examined, 56 were treated for osteoporotic vertebral compression fractures and 30 for vertebral tumors. .. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.6.2
- DOI:
- 10.4238/2015.March.6.2
Association between the C804A polymorphism in the TGF-�² gene and the risk of myocardial infarction: a meta-analysis
Authors: D.W. Suo, Q. Hu, J. Chen, Q.H. Sun and H. Guo
Tumor necrosis factor-β (TNF-β) is an important mediator of inflammation and may play a role in the pathogenesis of myocardial infarction (MI). While several published studies have investigated the association between the C804A polymorphism in the TNF-β gene and MI risk, their results are controversial and ambiguous. In this study, we evalu.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.6.4
- DOI:
- 10.4238/2015.March.6.4
Androgen receptor gene CAG repeat polymorphism and risk of isolated hypospadias: results from a meta-analysis
Authors: G. Huang, W. Shan, L. Zeng and L. Huang
Studies investigating the association between the CAG repeat polymorphism and the risk of isolated hypospadias have reported conflicting results. The aim of this study was to quantitatively summarize the evidence for such a relationship. Two investigators independently searched the Medline, Embase, CNKI, and Wanfang databases. Weighted mean difference and.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.6.5
- DOI:
- 10.4238/2015.March.6.5
Significance of Ebp1 and p53 protein expression in cervical cancer
Authors: L. Liu, X.D. Li, H.Y. Chen, J.S. Cui and D.Y. Xu
In this study, the ErbB3-binding protein (Ebp1) and p53 protein expression in cervical cancer tissues, and its significance in the prognosis of the disease was investigated. Ebp1 and p53 protein expression was detected by immunohistochemical analysis in cervical cancer tissues (N = 60) and normal tissues adjacent to the cancer.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.2.19
- DOI:
- 10.4238/2015.October.2.19
Risk factors associated with aortic remodeling in patients with Stanford type B aortic dissection after thoracic endovascular aortic repair
Authors: X.L. Wang, H.Y. Huang, Z. Li, Y.S. Yu, Y.Q. Hu, W.X. Ye, F. Hua, Y.H. Chen, H. Ni, Q.W. Ding and Z.Y. Shen
To determine the risk factors associated with adverse aortic remodeling after thoracic endovascular aortic repair (TEVAR) in patients with Stanford type B aortic dissection, we performed a retrospective analysis of 54 patients between January 2009 and June 2012 at the First Affiliated Hospital of Soochow University. All patien.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.2.2
- DOI:
- 10.4238/2015.October.2.2
Microdissection testicular sperm extraction causes spermatogenic alterations in the contralateral testis
Authors: A.B. Oliveira Filho, R.S. Souza, M.T.V. Azeredo-Oliveira, R.L. Peruquetti and A.P. Cedenho
Testicular sperm extraction (TESE) associated with intracytoplasmic sperm injection has allowed many men presenting non-obstructive azoospermia to achieve fatherhood. Microdissection TESE (microTESE) was proposed as a method to improve sperm retrieval rates in these patients; however, there have been failures. Little is known .. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr860
- DOI:
- 10.4238/vol9-3gmr860
Association of CYP2C19*3 gene polymorphism with breast cancer in Chinese women
Authors: C.Q. Gan, X.Y. Wang, Y.D. Cao, W.X. Ye, H. Liu and Y.Y. Sun
Cytochrome P450 (CYP) 2C19 metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids, which significantly promote proliferation of cancer cells in vitro and in vivo. We looked for a possible association between human CYP2C19*3 gene polymorphism and breast cancer in the Chinese Han population. In a Chinese H.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.5.3
- DOI:
- 10.4238/2011.December.5.3
Transcriptional analysis of the porcine TTID gene and association of different TTID genotypes with carcass traits
Authors: J. Wang, Y.-P. Feng, B. Zuo, Y.-Z. Xiong and C.-Y. Deng
The titin immunoglobulin domain (TTID) protein localizes to the Z line in muscle and binds to alpha-actinin and gamma-filamin. It plays an indispensable role in stabilizing and anchoring of thin filaments. In this study, the 5'-regulatory region of the porcine TTID gene was analyzed with bioinformatic methods. Another objectiv.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.February.27.4
- DOI:
- http://dx.doi.org/10.4238/2014.February.27.4
�²3-adrenergic receptor polymorphism is related to cardiometabolic risk factors in obese Brazilian subjects
Authors: V.A. Genelhu, E.A. Francischetti, S.F.P. Duarte, B.M.J. Celoria, R.C. Oliveira, P.H. Cabello and M.M.G. Pimentel
We determined whether ADRβ3 polymorphism is associated with obesity-related traits in 140 obese patients. Molecular analysis was performed by PCR and RFLP. Individuals carrying the Arg64 allele had a lower waist-to-hip ratio, higher adiponectin and high-density lipoprotein cholesterol levels, and a tendency towards lower .. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr819
- DOI:
- 10.4238/vol9-3gmr819
High frequency of microsatellite instability in sporadic colorectal cancer patients in Iran
Authors: M. Moghbeli, O. Moaven, E. Dadkhah, M. Farzadnia, N.M. Roshan, H. Asadzadeh-Aghdaee, M.M. Bahar, R. Raeisossadati, M.M. Forghanifard, S.R.E.A. Bakhtiari, A. Baradaran and M.R. Abbaszadegan
Microsatellite instability in sporadic colorectal cancer patients was assessed, and the clinicopathological associations were evaluated in northeastern Iran, which is a high-risk region for gastrointestinal malignancies. Microsatellite instability (MSI)status of tumoral tissue, compared to normal tissue, was assessed with a st.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.14.4
- DOI:
- 10.4238/2011.December.14.4