Animal Genetics
Association analysis of IGF-I gene expression with growth and reproductive traits in Jinghai yellow chickens
Authors: M.A. Abdalhag, T. Li, L. Duan, T. Zhang, G. Zhang, J. Wang and Y. Wang
The insulin-like growth factor, IGF-I, plays an important role in the development of growth and reproductive traits. Single-strand conformation polymorphism analysis was used to detect and analyze polymorphisms and expression profiles of the IGF-I gene and its association with growth and reproductive traits of Jinghai yellow c.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049205
- DOI:
- 10.4238/gmr15049205
Gene regulatory network identification from the yeast cell cycle based on a neuro-fuzzy system
Authors: B.H. Wang, J.W. Lim and J.S. Lim
Many studies exist for reconstructing gene regulatory networks (GRNs). In this paper, we propose a method based on an advanced neuro-fuzzy system, for gene regulatory network reconstruction from microarray time-series data. This approach uses a neural network with a weighted fuzzy function to model the relationships between genes. Fuzzy rules, which deter.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15039002
- DOI:
- 10.4238/gmr.15039002
Cells of the rectum of Bombyx mori affected by experimental inoculation with Alphabaculovirus
Authors: S.A. Vessaro-Silva, R.M.C. Brancalh�£o, M.P.D. Baggio and L.F.C. Ribeiro
Bombyx mori is an insect whose cocoon is used in the sericulture industry, which is an important activity in parts of southern Brazil. When parasitized by Bombyx mori nucleopolyhedrovirus (BmNPV) of the genus Alphabaculovirus (alphaBV), it develops nuclear polyhedrosis disease. In Brazil, an alphaBV .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.29.10
- DOI:
- 10.4238/2014.August.29.10
Effect of selective serotonin reuptake inhibitors on expression of 5-HT1AR and neurotransmitters in rats with vascular dementia
Authors: K. Guo, G. Yin, X.H. Zi, H.X. Zhu and Q. Pan
5-hydroxytryptamine receptor 1A (5-HT1AR) is closely associated with cognitive functions. Selective serotonin reuptake inhibitors (SSRIs) can protect individuals from brain damage following ischemia/hypoxia. To investigate the function of SSRIs in vascular dementia (VD), we established a rat model of VD, and observed the effec.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049031
- DOI:
- 10.4238/gmr15049031
Polymorphism in the 5�-UTR of the insulin-like growth factor I gene associated with production traits in Chinese cattle
Authors: L.-Z. Zhang, G. Ren, L.-S. Hua, X.-Y. Lan, C.-Z. Lei and H. Chen
The insulin-like growth factor I (IGF-1) gene plays important roles in the growth and body composition of animals. Serum IGF1 concentration has been associated with growth traits in many livestock species. We found a polymorphism of cattle IGF1-TasI locus and analyzed the distribution of alleles in three cattle breeds, includi.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.29.12
- DOI:
- 10.4238/2014.August.29.12
Characterization of the Toxoplasma gondii hsp60 gene sequences from different hosts and geographical locations
Authors: J. Lu, D.H. Zhou, J. Chen, N.Z. Zhang, R.A. Wang, Y.B. Weng and X.Q. Zhu
The intracellular protozoan Toxoplasma gondii is one of the most successful parasites, with the ability to invade all warm-blooded animals, including humans. T. gondii heat shock protein 60 (TgHSP60) plays an important role in intracellular survival and in the differentiation of the parasite, and is also recognized as being associated wi.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.29.13
- DOI:
- 10.4238/2014.August.29.13
Role of glutathione and other antioxidants in the inhibition of apoptosis and mesenchymal transition in rabbit lens epithelial cells
Authors: H.J. Wang, J. Zhu and G.Y. Zheng
This study aimed to discuss the effect and mechanism of glutathione (GSH) and catalase (CAT) on transforming growth factor beta (TGF-β)-induced lens epithelial cell (LEC) apoptosis and epithelial mesenchymal transition (EMT) to prevent and control cataracts. Healthy rabbits (4 weeks old) were randomly selected, and LECs f.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.1.1
- DOI:
- 10.4238/2014.September.1.1
Isolation and characterization of novel microsatellite markers from Siamese fighting fish (Betta splendens, Osphronemidae, Anabantoidei) and their transferability to related species, B. smaragdina and B. imbellis
Authors: V. Chailertrit, A. Swatdipong, S. Peyachoknagul, J. Salaenoi and K. Srikulnath
Ten novel microsatellite markers were developed and characterized from Siamese fighting fish (Betta splendens). Nine of ten markers were polymorphic, exhibiting an allelic number (NA) from 2 to 6 alleles per locus. The effective number of alleles (NE) ranged from 1.60 to 3.08 (average of 2.30). The observed (HO) and expected (.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.5.1
- DOI:
- 10.4238/2014.September.5.1
Knockdown of the putative Lifeguard homologue CG3814 in neurons of Drosophila melanogaster
Authors: P.G. M�Angale and B.E. Staveley
Lifeguard is an integral transmembrane protein that modulates FasL-mediated apoptosis by interfering with the activation of caspase 8. It is evolutionarily conserved, with homologues present in plants, nematodes, zebra fish, frog, chicken, mouse, monkey, and human. The Lifeguard homologue in Drosophila, CG3814, contains the Ba.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049290
- DOI:
- 10.4238/gmr15049290
Drosha, DGCR8, and Dicer mRNAs are downregulated in human cells infected with dengue virus 4 - Genet. Mol. Res. 15 (2): gmr.15027891 Drosha, Dicer, and TRBP mRNA are downregulated in Vero cells with the 3 UTR of Dengue virus
Authors: J.A. Castillo and S. Urcuqui-Inchima
A recent paper (Casseb et al., 2016) published in the journal Genetics and Molecular Research described the interesting concept that dengue virus (DENV)-4 infection, in the human cell line A-549, leads to the downregulation of expression of key components of microRNA (miRNA) biogenesis, such as Drosha, Dicer, and DGCR8. For th.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15039050
- DOI:
- 10.4238/gmr.15039050