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Effect of different compounds on the induction of laccase production by Agaricus blazei
Authors: J.S. Valle, L.P.S. Vandenberghe,A.C.C. Oliveira, M.F. Tavares,G.A. Linde, N.B. Colauto, C.R. Soccol
Laccases are polyphenol oxidases produced by many fungi and have many applications in textile, food and beverage, and pulp and paper industries. Laccase production can be induced using aromatic or phenolic compounds that mostly affect the transcription of laccase-encoding genes. In this study, we analyzed laccase and biomass p.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.40
- DOI:
- 10.4238/2015.December.1.40
Effect of the IkB�± mutant gene delivery to mesenchymal stem cells on rat chronic pancreatitis
Authors: T. Qin, C.J. Liu, H.W. Zhang, Y.F. Pan Q. Tang, J.K. Liu,Y.Z. Wang M.X. Hu and F. Xue
This study aimed to investigate the effect of inhibitors of the NF-kΒ alpha mutant gene (IkBaM) delivery to mensenchymal stem cells (MSCs) on rat chronic pancreatitis (CP). A total of 120 Sprague-Dawley rats were randomly divided into 6 groups of 20: Group A was injected with sterile saline solution, Group B was injected .. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.21.5
- DOI:
- 10.4238/2014.January.21.5
Molecular cloning and characterization of a novel chicken gene named grni
Authors: Y. Hua, D.Y. Hui, Z.H. Rong and T. Cheng
The full-length cDNA sequence of a novel expressed sequence tag (GenBank accession No. HQ184338) that was differentially expressed during Newcastle disease virus (NDV) infection in chickens was cloned from the chicken spleen by a rapid amplification of cDNA ends assay. This gene was further analyzed using bioinformatic methods.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.21.6
- DOI:
- 10.4238/2014.January.21.6
Regulation of human alpha-globin gene expression and alpha-thalassemia
Authors: D.M. Ribeiro and M.F. Sonati
Hemoglobin and globin genes are important models for studying protein and gene structure, function and regulation. We reviewed the main aspects of regulation of human α-globin synthesis, encoded by two adjacent genes (α2 and α1) clustered on chromosome 16. Their expression is controlled mainly by a regulatory element located 40 kb upstre.. Read More»
- Genet. Mol. Res. 7(4):
- vol7-4gmr472
- DOI:
- 10.4238/vol7-4gmr472
Transcriptional profiles of emasculated flowers of black locust (Robinia pseudoacacia) determined using the cDNA-AFLP technique
Authors: J.X. Wang, P. Sun, C.Q. Yuan, L. Dai, Y. Zhang, B. Wu, C. Long, Y.H. Sun, Y. Li
Black locust (Robinia pseudoacacia) is a tree in the subfamily Faboideae, native to North America, that has been naturalized and widely planted in temperate Europe and Asia. Black locust has important ecological and economic value, but its quality needs improvement. Hybridization programs are important for black locust breedin.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.34
- DOI:
- 10.4238/2015.December.1.34
Relationship between the HLA-G 14bp insertion/deletion polymorphism and susceptibility to autoimmune disease: a meta-analysis
Authors: S.K. Kim, K.H. Jeong,I.J. Kang, J.H. Chung, M.K. Shin, M.H. Lee
Numerous studies have investigated the potential relationship between the human leukocyte antigen (HLA)-G 14-bp insertion/deletion (INS/DEL) polymorphisms and autoimmune disease (AID). However, published results are inconclusive. Our aim was to determine whether the 14-bp INS/DEL polymorphism in the HLA-G gene contributes to t.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.35
- DOI:
- 10.4238/2015.December.1.35
Biological characteristics and mating type distribution of Phytophthora capsici from China
Authors: Y. Du, Z.-H. Gong, G.-Z. Liu, G.-X. Chai and C. Li
Phytophthora capsici from seven provinces of China were investigated for their mating type, hyphal growth, zoospore production, and virulence. All of the morphological characteristics and the results of polymerase chain reaction confirmed that these isolates were indeed Phytophthora capsici. The test of mating type showed that.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.21.7
- DOI:
- 10.4238/2014.January.21.7
A molecular study on the evolution of a subtype B variant frequently found in Brazil
Authors: M.E. Pinto1, C.G. Schrago1, A.B. Miranda2 and C.A.M. Russo1
In spite of the remarkable diversity of HIV-1 env genes, several amino acids are extremely conserved, probably due to functional constraints. One example is the proline found at the second position of the GPGR motif. Several viruses, however, bear substitutions at this site, for instance, GWGR subtype B variant. GWGR viruses are described in Brazil since .. Read More»
- Genet. Mol. Res. 7(4):
- vol7-4gmr383
- DOI:
- 10.4238/vol7-4gmr383
Role of interleukin-10 gene polymorphisms in the development of coronary artery disease in Chinese population
Authors: H.M. Xu,Y.R. Liu
The aim of this study was to investigate the association between three common SNPs (-1082A/G, -819T/C, and -592A/C) in the interleukin 10 (IL-10) gene, and the development of coronary artery disease. Between January 2013 and December 2014, 272 patients with coronary artery disease and control subjects (each) were recruited for.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.38
- DOI:
- 10.4238/2015.December.1.38
Species identification of Malayan Gaur, Kedah-Kelantan and Bali cattle using polymerase chain reaction-restricted fragment length polymorphism
Authors: S.M.N. Romaino, Z.A. Fazly-Ann, S.S. Loo, M.M. Hafiz, M.D. Hafiz, M.I. Iswadi, P. Kashiani, M.K.A. Rosli, S.M.F. Syed-Shabthar, B.M. Md-Zain and O. Abas-Mazni
Mitochondrial DNA (mtDNA) is a useful genetic marker that can be used for species identification. The cytochrome b (Cyt b) gene is a suitable mtDNA candidate gene for use in phylogenetic analyses due to its sequence variability, which makes it appropriate for comparisons at the subspecies, species, and genus levels. This study.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.21.8
- DOI:
- 10.4238/2014.January.21.8