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Dynamic comparison ofgeneticdiversity in a Small Tail Han sheep population using meta-analysis
Authors: G.X. E1, Y.F. Huang1, Y.J. Zhao1, J.N. He2, N. Liu2, T. Zhong3, Y.H. Ma4, X.Y. Qiu1 and L.P. Chen1
The aim of this research was to identify the dynamic diversity of Small Tail Han sheep in its main producing areas between different years, and provide a basis for a breeding and genetic resources conservation strategy. For this purpose, 15 microsatellites were genotyped for Small Tail Han Sheep sampled in 2014 from Heze, China, and a comparative analysis.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.24
- DOI:
- 10.4238/2015.November.18.24
Gene expression profiles in the pituitary glands of Sichuan White geese during prelaying and laying periods
Authors: G.L. Gao, X.Z. Zhao, Q. Li, J. Su and Q.G. Wang
To better understand the molecular mechanism(s) underlying egg-laying in Sichuan white geese, the profiles of genes in the pituitary gland were investigated during the prelaying and laying periods. Total RNA was extracted from the pituitary glands of geese during prelaying or laying periods and cDNA was generated. After sequen.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.7
- DOI:
- 10.4238/2015.October.19.7
Prenatal diagnosis of Chinese families with phenylketonuria
Authors: N. Liu1, X.D. Kong1, D.H. Zhao2, Q.H. Wu1, X.L. Li2, H.F. Guo4, L.X. Cui4,M. Jiang1 and H.R. Shi3
The aim of this study is to investigate the ability to prenatally diagnose phenylketonuria (PKU) by using phenylalanine hydroxylase (PAH) gene mutation analysis combined with short tandem repeat (STR) linkage analysis in 118 fetuses from 112 Chinese families. Genomic DNA was extracted from the peripheral blood from members of 112 families and the exons an.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.25
- DOI:
- 10.4238/2015.November.18.25
Variations in WNT3 gene are associated with incidence of non-syndromic cleft lip with or without cleft palate in a northeast Chinese population
Authors: Y.P. Lu, W.T. Han, Q. Liu, J.X. Li, Z.J. Li, M. Jiang and W. Xu
Non-syndromic cleft lip with or without cleft palate (NSCL/P) is a common birth defect. Several WNT genes are involved in craniofacial embryogenesis, and therefore may play an important role in the etiology of NSCL/P. Two SNPs (rs3809857 and rs9890413) in the WNT3 gene were subjected to case-control and case-parent analysis by.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.8
- DOI:
- 10.4238/2015.October.19.8
Complete mitochondrial genome and codon usage of the Nepalese whiskered bat Myotis muricola (Vespertilionidae)
Authors: K.B. Yoon and Y.C. Park
We sequenced and characterized the complete mitogenome of the Nepalese whiskered bat Myotis muricola (Vespertilionidae) to provide more data for comparative mitogenomics and codon usage in the genus Myotis (Vespertilionidae). The mitogenome of M. muricola is a circular molecule of 17,224 bp, consisting of a control region and a conserved set of 37 genes c.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.27
- DOI:
- 10.4238/2015.November.18.27
Evaluation of soybean lines and environmental stratification using the AMMI, GGE biplot, and factor analysis methods
Authors: L.B. Sousa, O.T. Hamawaki, A.P.O. Nogueira, R.O. Batista, V.M. Oliveira and R.L. Hamawaki
In the final phases of new soybean cultivar development, lines are cultivated in several locations across multiple seasons with the intention of identifying and selecting superior genotypes for quantitative traits. In this context, this study aimed to study the genotype-by-environment interaction for the trait grain yield (kg/.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.19.10
- DOI:
- 10.4238/2015.October.19.10
Relationship between SPOP mutation and breast cancer in Chinese population
Authors: M.A. Khan, L. Zhu, M. Tania, X.L. Xiao and J.J. Fu
SPOP protein has been found to have ubiquitin ligase activity. Mutations in SPOP gene have been recently reported in some cancers such as prostate, gastric, colorectal cancer. We investigated SPOP DNA mutation in tumor tissues collected from 70 Chinese female breast cancer patients in Southwestern China by DNA sequencing. The .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.16.2
- DOI:
- 10.4238/2015.October.16.2
Cloning and expression of the sucrose transporter gene PsSUT1 from tree peony leaf
Authors: Y.H. Li, T. Guo, Y. Cui , Y. Li and D. He
This study reports the cloning of a sucrose transporter gene, PsSUT1, from the leaf of tree peony (Paeonia suffruticosa Lind. cv ‘Huhong’). Expression patterns were examined in different organs and at different developmental stages. The full-length cDNA of PsSUT1 consisted of a 2001-bp sequence containing a 1557-bp.. Read More»
- Genet. Mol. Res. 14(4):
- Y.H. Li*, T. Guo*, Y. Cui , Y. Li and D. He
- DOI:
- Y.H. Li*, T. Guo*, Y. Cui , Y. Li and D. He
Effects of high intensity exhaustive exercise on SOD, MDA, and NO levels in rats with knee osteoarthritis
Authors: X.D. Li, G.F. Sun, W.B. Zhu and Y.H. Wang
The aim of this study was to investigate the impact of high intensity exhaustive exercise on nitric oxide (NO), malondialdehyde (MDA), and superoxide dismutase (SOD) expression in rats with knee osteoarthritis. Sprague Dawley rats were randomly divided into control (N = 5) and model (N = 35) groups; the model group was further.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.16.3
- DOI:
- 10.4238/2015.October.16.3
Association between hypoxia-inducible factor-1a levels in serum and synovial fluid with the radiographic severity of knee osteoarthritis
Authors: H. Chu, Z.M. Xu, H. Yu, K.J. Zhu and H. Huang
Osteoarthritis (OA) is primarily characterized by articular cartilage degradation. Hypoxia-inducible factor-1a (HIF-1a), a subunit of the basic helix-loop-helix-containing PER-ARNT-SIM (PAS) domain transcription factors, plays a vital role in the survival of articular chondrocytes to the hostile hypoxic microenvironment and complicates the progression of .. Read More»
- Genet. Mol. Res. 13(4):