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Screening and prevention of neonatal glucose 6-phosphate dehydrogenase deficiency in Guangzhou, China
Authors: J. Jiang, B. Li, W. Cao, X. Jiang, X. Jia, Q. Chen and J. Wu
We aimed to summarize the results of screening protocol and prevention of neonatal glucose 6-phosphate dehydrogenase (G6PD) deficiency during a 22-year-long period to provide a basis of reference for the screening of this disease. About 1,705,569 newborn subjects in Guangzhou City were screened for this deficiency. Specimens w.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.June.9.13
- DOI:
- http://dx.doi.org/10.4238/2014.June.9.13
Single nucleotide polymorphism screening, molecular characterization, and evolutionary aspects of chicken Piwi genes
Authors: H.Z. Wang, T. Ma, G.B. Chang, F. Wan, X.P. Liu, L. Lu, L. Xu, J. Chen and G.H. Chen
The P-element-induced wimpy testis (Piwi) gene is involved in germline stem cell self-renewal, meiosis, RNA silencing, and transcriptional regulation. Piwi genes are relatively well conserved in many species, but their function in poultry species is unclear. In this study, Piwi genes were sequenced u.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.45
- DOI:
- 10.4238/2015.November.18.45
High MMP-1, MMP-2, and MMP-9 protein levels in osteoarthritis
Authors: G.Q. Zeng, A.B. Chen, W. Li, J.H. Song and C.Y. Gao
Our study examined the relationship between the expression of matrix metalloproteinases (MMP)-1, MMP-2, and MMP-9 proteins and the pathogenesis of osteoarthritis (OA). We employed rigorous inclusion and exclusion criteria in computer-based bibliographic databases to extract published studies relevant to this investigation. The.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.46
- DOI:
- 10.4238/2015.November.18.46
High proportion of mannosidosis and fucosidosis among lysosomal storage diseases in Cuba
Authors: C. MenÃ?©ndez-Sainz, A. GonzÃ?¡lez-Quevedo, S. GonzÃ?¡lez-GarcÃ?Âa, M. PeÃ?±a-SÃ?¡nchez and R. Giugliani
Although lysosomal storage disorders (LSDs) are considered individually rare, as a group they present a non-negligible frequency. Few studies have been made of populational occurrence of LSDs; they have been conducted predominantly on Caucasian populations. We studied the occurrence of LSDs in Cuba. Data from individuals who had been referred to the Insti.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.August.13.9
- DOI:
- 10.4238/2012.August.13.9
Differential expression of resistance to powdery mildew at the early stage of development in wheat line N0308
Authors: M.A. Alam, W. Hongpo, Z. Hong and W.Q. Ji
Powdery mildew, caused by Blumeria graminis f. sp tritici (Bgt) is one of the devastating diseases of wheat and causes yield losses in temperate wheat growing regions. A wheat line, N0308 with resistance to powdery mildew was used in this study. A suppression subtractive hybridization cDNA library was constructed from the whea.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.June.9.15
- DOI:
- http://dx.doi.org/10.4238/2014.June.9.15
Development of primer pairs from diverse chloroplast genomes for use in plant phylogenetic research
Authors: Y.C. Yang, T.L. Kung, C.Y. Hu and S.F. Lin
Variation in the chloroplast DNA sequence is useful for plant phylogenetic studies. However, the number of variable sequences provided by chloroplast DNA for suggested genes or genomic regions in plant phylogenetic analyses is often inadequate. To identify conserved regions that can be used to design primers and amplify variab.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.51
- DOI:
- 10.4238/2015.November.18.51
Familial balanced translocation leading to an offspring with phenotypic manifestations of 9p syndrome
Authors: L.S. Abreu, M.S. Brassesco, M.L.C. Moreira, J.M. Pina-Neto
We report two similarly affected cousins (children of monozygotic twin sisters) with phenotypic features consistent with 9p deletion syndrome, including dysmorphic craniofacial features (trigonocephaly, midface hypoplasia, upward-slanting palpebral fissures and long philtrum), intellectual disability and disorders of sex devel.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.June.9.16
- DOI:
- http://dx.doi.org/10.4238/2014.June.9.16
Molecular cloning and expression of drought-induced protein 3 (DIP3) encoding a class III chitinase in upland rice
Authors: X.L. Guo, L.R. Bai, C.Q. Su, L.R. Shi and D.W. Wang
A drought-induced gene, DIP3, encoding a chitinase III protein was isolated from the roots of upland rice by reverse transcription-polymerase chain reaction (RT-PCR). Sequence analysis demonstrated that the cDNA and deduced protein showed high identity to Oryza sativa class III chitinase. The deduced protein contained a signal peptide sequence in the N-te.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.19.5
- DOI:
- 10.4238/2013.December.19.5
Cloning and characterization of a �²-amyrin synthase gene from the medicinal tree Aralia elata (Araliaceae)
Authors: Y. Wu, H.D. Zou, H. Cheng, C.Y. Zhao, L.F. Sun, S.Z. Su, S.P. Li and Y.P. Yuan
Aralia elata is an important medicinal plant in China; it produces large amounts of oleanane type triterpene saponins. A full-length cDNA encoding β-amyrin synthase (designated as AeAS) was isolated from young leaves of A. elata by reverse transcription-PCR. The full-length cDNA of AeAS was found to have a 2292-bp open reading frame, encoding a prote.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.August.13.4
- DOI:
- 10.4238/2012.August.13.4
Propofol induces apoptosis and inhibits the proliferation of rat embryonic neural stem cells via gamma-aminobutyric acid type A receptor
Authors: J.W. Wang, W.W. Cheng, T. Xu and Z.Y. Yang
We investigated the effect of propofol on the proliferation and viability of rat embryonic neural stem cells (rENSCs) and the potential mechanisms involved. rENSCs were isolated and cultured in vitro and treated with 1, 10, or 50 μM propofol, while the control group was treated with 0.1 μM dimethyl sulfoxide. Th.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.57
- DOI:
- 10.4238/2015.November.18.57