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Correlation of serum high-sensitivity C-reactive protein and interleukin-6 in patients with acute coronary syndrome
Authors: X.H. Wang, S.Q. Liu, Y.L. Wang and Y. Jin
Serum high-sensitivity C-reactive protein (hs-CRP) is a sensitive indicator of inflammation, which is closely related with the progress of plaque formation. Interleukin-6 (IL-6) is one of the inflammatory markers of local coronary plaque and the peripheral blood cycle, promoting the occurrence of atherosclerosis development an.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.June.9.11
- DOI:
- http://dx.doi.org/10.4238/2014.June.9.11
Thirty-four Musa (Musaceae) expressed sequence tag-derived microsatellite markers transferred to Musella lasiocarpa
Authors: W.J. Li, H. Ma, Z.H. Li, Y.M. Wan, X.X. Liu and C.L. Zhou
We assembled 31,308 publicly available Musa EST sequences into 21,129 unigenes; 4944 of them contained 5416 SSR motifs. In all, 238 unigenes flanking SSRs were randomly selected for primer design and then tested for amplification in Musella lasiocarpa. Seventy-eight primer pairs were found to be transferable to this species, and 49 displayed polymorphism... Read More»
- Genet. Mol. Res. 11(3):
- 2012.August.6.13
- DOI:
- 10.4238/2012.August.6.13
Molecular combing in the analysis of developmentally regulated amplified segments of Bradysia hygida
Authors: K.J.R. Passos, S.Y. Togoro, S. Carignon, S. Koundrioukoff, A.-M. Lachages, M. Debatisse and M.A. Fernandez
Molecular combing technology is an important new tool for the functional and physical mapping of genome segments. It is designed to identify amplifications, microdeletions, and rearrangements in a DNA sequence and to study the process of DNA replication. This technique has recently been used to identify and analyze the dynamics of replication in amplified.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.August.6.10
- DOI:
- 10.4238/2012.August.6.10
Molecular characterization of Corynebacterium pseudotuberculosis isolated from goats using ERIC-PCR
Authors: E.M.S. Dorneles, J.A. Santana, G.I. Andrade, E.L.S. Santos, A.S. Guimar�£es, R.A. Mota, A.S. Santos, A. Miyoshi, V. Azevedo, A.M.G. Gouveia, A.P. Lage and M.B. Heinemann
Corynebacterium pseudotuberculosis, the infectious agent of caseous lymphadenitis (CLA), is responsible for substantial economic losses in goat and sheep production. Molecular characterization of C. pseudotuberculosis isolates by enterobacterial repetitive intergenic consensus (ERIC)-PCR has shown promising results in genotyping strains isolated from shee.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.August.6.9
- DOI:
- 10.4238/2012.August.6.9
Effect of different carbon sources on proteases secreted by the fungal pathogen Sclerotinia sclerotiorum during Phaseolus vulgaris infection
Authors: E.A. Bueno, M.B. Oliveira, R.V. Andrade, M. Lobo Junior and S. Petrofeza
Sclerotinia sclerotiorum (Sclerotiniaceae) is a plant pathogenic fungus that causes white mold disease in vegetable crops, including the common bean (Phaseolus vulgaris). Proteases produced by fungi are normally an important part of the pathogenic process in the host. We examined the effect of different carbon sources - pectin, glucose, and cell wall of P.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.June.25.3
- DOI:
- 10.4238/2012.June.25.3
Association of the g.27563G>A osteoprotegerin genetic polymorphism with bone mineral density in Chinese women
Authors: Y.P. Liu, D.W. Zhao, W.M. Wang, B.J. Wang, Y. Zhang and Z.G. Li
Osteoporosis is a common multifactorial disease in postmenopausal women. This study aimed to investigate the association of the g.27563G>A osteoprotegerin (OPG) genetic polymorphism with bone mineral density (BMD) and osteoporosis. A case-control study was carried out with 435 osteoporosis postmenopausal women cases and 442.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.February.14.9
- DOI:
- 10.4238/2014.February.14.9
Meta analysis of angiotensin-converting enzyme I/D polymorphism as a risk factor for preeclampsia in Chinese women
Authors: W.G. Zhong, Y. Wang, H. Zhu and X. Zhao
Preeclampsia affects 3-8% of pregnancies and is a major cause of maternal and perinatal morbidity and mortality worldwide. Inappropriate activation of the renin-angiotensin system may play a role in the development of preeclampsia. An insertion/deletion polymorphism in the angiotensin-converting enzyme gene (ACE-I/D) has been associated with differences i.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.May.21.1
- DOI:
- 10.4238/2012.May.21.1
KDR gene silencing inhibits proliferation of A549cells and enhancestheir sensitivity to docetaxel
Authors: R. Wei and J.-P. Zang
We investigated the effects of kinase-domain insert containing receptor (KDR) gene silencing on the proliferation of A549 cells and their sensitivity to docetaxel. After designing and synthesizing the KDR siRNA sequence, the sequence was transfected into A549 cells using Lipofectamine 2000. The expression of KDR.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.18.43
- DOI:
- 10.4238/2015.November.18.43
Microarray-based gene expression profiles in rabbit retina due to negative pressure suction
Authors: H.X. Zhao, C.M. Niu and W.Y. Guan
We investigated a possible molecular pathogenesis involving retinal ganglion cell apoptosis following transient high intraocular pressure. Changes in the gene expression profiles of the retina were detected via gene chip methodology. Twelve New Zealand white rabbits were randomly assigned to control and 3-min negative pressure suction groups. The control .. Read More»
- Genet. Mol. Res. 11(3):
- 2012.May.18.9
- DOI:
- 10.4238/2012.May.18.9
Novel nonsense and frameshift NTRK1 gene mutations in Chinese patients with congenital insensitivity to pain with anhidrosis
Authors: M. Li, J.Y. Liang, Z.H. Sun, H. Zhang and Z.R. Yao
Congenital insensitivity to pain with anhidrosis (CIPA; MIM 256800) is a rare autosomal recessive disorder characterized by absence of reaction to noxious stimuli, recurrent episodes of fever, anhidrosis, and mental retardation. It is caused by mutations in the gene coding for neurotrophic tyrosine kinase receptor type 1 (NTRK1; MIM# 191315). We screened .. Read More»
- Genet. Mol. Res. 11(3):
- 2012.May.18.8
- DOI:
- 10.4238/2012.May.18.8