Se
Roles of Fas/Fasl, Bcl-2/Bax, and Caspase-8 in rat nonalcoholic fatty liver disease pathogenesis
Authors: C.P. Li, J.H. Li, S.Y. He, P. Li and X.L. Zhong
The aim of this study was to investigate the roles of Fas/FasL, Bcl-2/Bax, and Caspase-8 mRNA expressions in nonalcoholic fatty liver disease (NAFLD). The apoptosis percentage was measured by flow cytometry, the immunohistochemical assay was performed for the determination of Fas, FasL, Bcl-2, and Bax expressions, and a real-t.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.23.10
- DOI:
- http://dx.doi.org/10.4238/2014.May.23.10
Bulked segregant analysis of the pirarucu (Arapaima gigas) genome for identification of sex-specific molecular markers
Authors: I.G. Almeida, P. Ianella, M.T. Faria, S.R. Paiva and A.R. Caetano
Arapaima gigas (Osteoglossidae) is one of the largest fish species in the Amazon Basin, attaining lengths of over 2.5 m and weights of over 100 kg. Its flesh is prized, and it has great potential for production in aquaculture systems. However, live pirarucu cannot be reliably sexed visually, even after sexual development, since this species does not have .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.4.17
- DOI:
- 10.4238/2013.December.4.17
Identification of the isoamylase 3 gene in common wheat and its expression profile during the grain-filling period
Authors: G.Z. Kang, G.Q. Liu, W. Xu, Y.J. Zhu, C.Y. Wang, H.Q. Ling and T.C. Guo
In higher plants, isoamylase-type starch debranching enzyme catalyzes the α-1,6-glucosidic linkages of glycogen and phytoglycogen. We cloned an isoamylase-type starch debranching enzyme ISA3 cDNA sequence (2883 bp), designated as TaISA3, from common wheat (Triticum aestivum), using the rapid amplification of cDNA ends method. The open reading frame .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.February.28.17
- DOI:
- 10.4238/2013.February.28.17
Associations between clinical characteristics and oncogene expression in patients with non-small cell lung cancer
Authors: Y. Han, D.P. Yu, S.J. Zhou, X.Y. Song, Y.S. Li, N. Xiao, Z.D. Liu, X.J. Sun, Q.Y. Zhao and S.K. Liu.
More than 40 oncogenes associated with non-small cell lung cancer (NSCLC) have been identified with varied gene expression. The correlations between specific clinical characteristics and oncogene expression in NSCLC patients were examined. From October 2011 to September 2012, a total of 60 patients with NSCLC (male:female, 34:24; mean age, 59.5 ± 1.. Read More»
- Genet. Mol. Res. 13(4):
Registries of cleft lip/palate cases between 2004 and 2010 in Denizli, Turkey
Authors: A.G. Tomat�±r, I. Acikbas, B. Akdag and A. K�¶ksal
Oral clefts are one of the most common birth defects in humans. However, few population-based studies of these defects have been carried out in Turkey. Our objective was to determine the registries of cases of cleft lip and palate. All cases of cleft lip and palate referred to central state hospitals in Denizli between January 2000 and May 2010 were inves.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.February.19.4
- DOI:
- 10.4238/2013.February.19.4
Molecular cloning and expression analysis of two sex-lethal homolog genes during development in the oriental river prawn, Macrobrachium nipponense
Authors: Y.P. Zhang, H. Qiao, W.Y. Zhang, S.M. Sun, S.F. Jiang, Y.S. Gong, Y.W. Xiong, S.B. Jin and H.T. Fu
In this study, two Sxl gene homologs, designated as Mnsxl1 and Mnsxl2, were cloned and characterized from the freshwater prawn Macrobrachium nipponense by rapid amplification of cDNA ends. The deduced amino acid sequences of Mnsxl1 and Mnsxl2 showed high sequence homology to the insect Sxl and contained conserved domains in two RNA-binding motifs. Real-ti.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.18.8
- DOI:
- 10.4238/2013.October.18.8
ReSeqTools: an integrated toolkit for large-scale next-generation sequencing based resequencing analysis
Authors: W. He, S. Zhao, X. Liu, S. Dong, J. Lv, D. Liu, J. Wang and Z. Meng
Large-scale next-generation sequencing (NGS)-based resequencing detects sequence variations, constructs evolutionary histories, and identifies phenotype-related genotypes. However, NGS-based resequencing studies generate extraordinarily large amounts of data, making computations difficult. Effective use and analysis of these data for NGS-based resequencin.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.4.15
- DOI:
- 10.4238/2013.December.4.15
Prevalence and genotypic diversity of cervical human papillomavirus infection among women from an urban center in Brazil
Authors: J. Coser, T. da Rocha Boeira, D. Simon, A.S. Kazantzi Fonseca, N. Ikuta and V.R. Lunge
Human papillomavirus (HPV) infection is a common viral sexually transmitted infection and the main cause of cervical cancer in women worldwide. Epidemiological data on the prevalence of HPV in a given population is essential for the establishment of effective prevention strategies. The aim of this study was to determine HPV prevalence in women who attende.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.February.19.3
- DOI:
- 10.4238/2013.February.19.3
Variability and performance evaluation of introgressed Nigerian dura x Deli dura oil palm progenies
Authors: A. Noh, M.Y. Rafii, A. Mohd Din, A. Kushairi, A. Norziha, N. Rajanaidu, M.A. Latif and M.A. Malek
Twelve introgressed oil palm (Elaeis guineensis) progenies of Nigerian dura x Deli dura were evaluated for bunch yield, yield attributes, bunch quality components and vegetative characters at the Malaysian Palm Oil Board Research Station, in Keratong, Pahang, Malaysia. Analysis of variance revealed significant to highly signif.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.3.15
- DOI:
- 10.4238/2014.April.3.15
N-terminal functional region of the invariant chain efficiently targets the binding of a CTL epitope to MHC class I molecules during cross-presentation
Authors: C. Wu, D.G. Zhang, F.F. Chen, X.L. Liu, S.J. Liu and W.Y. Yu
Cross-presentation (CP) is important for priming T cell responses to many viral, bacterial, and tumor antigens. Here, we designed two Ii mutants, based on evidence that the invariant chain (Ii, also named CD74) binds newly synthesized MHC class I molecules with the class II-associated invariant chain peptide (CLIP) region of I.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.3.16
- DOI:
- 10.4238/2014.April.3.16