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Animal Genetics   Original Articles

Hematological and biochemical changes in a Phrynops geoffroanus (Schweigger, 1812) population in response to environmental stressors

Authors: M.I.A. Silva

Turtles are among the most endangered vertebrate groups, and the main threats to populations are environmental pollution and habitat degradation. The species Phrynops geoffroanus, popularly known as “Geoffroy’s side-necked turtle”, has proliferated in polluted environments, where adverse conditions could infl.. Read More»

Genet. Mol. Res. 10(2):
vol10-2ta037
DOI:
10.4238/vol10-2ta037
Medical Genetics   Research Article

Analysis and clinical significance of microRNA-499 expression levels in serum of patients with acute myocardial infarction

Authors: C.H. Zhao,G.-C. Cheng,R.L. He,Y. Hong,Q.L. Wan,Z.-Z. Wang and Z.-Y. Pan

The aim of this study was to investigate the expression level of microRNA-499 and its clinical significance in serum of patients with acute myocardial infarction (AMI). We recruited 59 patients with AMI and 60 healthy individuals undergoing physical examination in our hospital during the same period as controls. Peripheral blood was drawn in the morning o.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.27.17
DOI:
http://dx.doi.org/10.4238/2015.April.27.17
Plant Genetics   Research Article

Altered callose deposition during embryo sac formation of multi-pistil mutant (mp1) in Medicago sativa

Authors: H.C. Zhou, L. Jin, J. Li and X.J. Wang

Whether callose deposition is the cause or result of ovule sterility in Medicago sativa remains controversial, because it is unclear when and where changes in callose deposition and dissolution occur during fertile and sterile embryo sac formation. Here, alfalfa spontaneous multi-pistil mutant (mp1) and wild-type plants were u.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027968
DOI:
10.4238/gmr.15027968
Animal Genetics   Research Article

Cloning and functional analysis of goat SWEET1

Authors: L.Q. Zhu, Z.K. Bao, W.W. Hu, J. Lin, Q. Yang and Q.H. Yu

SWEETs are a recently discovered class of sugar transporters that mediate glucose uptake in the intestine and mammary glands. Our objectives were to clone goat SWEET1 and conduct a functional analysis of its effect on glucose efflux in goat mammary gland epithelial cells. We cloned and sequenced the goat SWEET1 gene from goat mammary glands, then conducte.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.12
DOI:
10.4238/2015.December.16.12
Human Genetics   Research Article

Analysis of genetic diversity of Laeliinae (Orchidaceae) in the State of Sergipe using ISSR markers

Authors: M.F. Arrigoni-Blank, M.S. Santos, A.F. Blank, A.R.C. Rabbani, R. Silva-Mann, J.B. Santos, A.S. Costa and T.S.A. Menezes

The Orchidaceae represent one of the largest and most diverse families on the planet. However, this family is constantly threatened by predators and by the advancement of urban centers over its natural habitats. The objective of this study was to use inter-simple sequence repeat markers to evaluate the genetic diversity betwee.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027997
DOI:
10.4238/gmr.15027997
Animal Genetics   Research Article

New polymorphic microsatellite loci of threadsail filefish, Stephanolepis cirrhifer (Teleostei, Monacanthidae), from Korean waters

Authors: C.-M. An, H.S. An, J.W. Lee and S.W. Hong

The threadsail filefish, Stephanolepis cirrhifer (Monacanthidae), is found mainly in the western Pacific. It is intensively caught in Korea and is a highly appreciated seafood delicacy. Consequently, the natural population of this species has drastically decreased, despite introductions from hatcheries. To provide information necessary for its conservatio.. Read More»

Genet. Mol. Res. 12(2):
2013.May.14.8
DOI:
10.4238/2013.May.14.8
Human Genetics   Research Article

Study of the relationship between IL-10 polymorphism and serum lipoprotein levels in Han Chinese individuals

Authors: W.Q. Yang

Previous studies have shown that cytokines can affect serum lipoprotein concentrations. The aim of this study was to examine the association between IL-10 gene polymorphisms and serum lipoprotein levels of Han Chinese individuals. A total of 359 Han Chinese people were enrolled in this investigation. IL-10 -592, -819, and -108.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028016
DOI:
10.4238/gmr.15028016
Plant Genetics   Research Article

Isolation and characterization of microsatellite markers for Osmanthus fragrans (Oleaceae) using 454 sequencing technology

Authors: W.J. Yuan, Y. Li, Y.F. Ma, Y.J. Han and F.D. Shang

Osmanthus fragrans (Oleaceae) is an evergreen shrub or small tree that grows in south China. In this study, Roche 454 FLX+ sequencing combined with the magnetic bead enrichment method was used to isolate microsatellite markers from the genome of O. fragrans. A total of 1471 microsatellites that contained enough flanking sequences for primer pair design we.. Read More»

Genet. Mol. Res. 14(4):
2015.December.16.15
DOI:
10.4238/2015.December.16.15
Human Genetics   Research Article

Single-nucleotide polymorphisms in dopamine receptor D1 are associated with heroin dependence but not impulsive behavior

Authors: J.H. Liu,H.J. Zhong,J. Dang,L. Peng and Y.S. Zhu

Previous studies suggested that dopamine receptors may be associated with drug dependence and impulsive behavior. In this study, we examined whether dopamine receptor D1 (DRD1) is associated with heroin dependence and the impulsive behavior in patients with heroin dependence. The participants included 367 patients with heroin dependence and 372 healthy co.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.27.19
DOI:
http://dx.doi.org/10.4238/2015.April.27.19
Human Genetics   Research Article

Association between NOS3 genetic variants and coronary artery disease in the Han population

Authors: G.L. Zhao, Q.J. Li and H.Y. Lu

The enzyme endothelial nitric oxide synthase (NOS3) is an important mediator of atherosclerotic disease and is associated with coronary artery disease (CAD). There is growing evidence that polymorphisms in NOS3 influence the progression of CAD; however, there is also a controversy regarding the association of polymorphisms in .. Read More»

Genet. Mol. Res. 15(2):
gmr.15028044
DOI:
10.4238/gmr.15028044